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Accurate cancer survival prediction is crucial for assisting clinical doctors in formulating treatment plans. Multimodal data, including histopathological images and genomic data, offer complementary and comprehensive information that can…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Hui Luo , Jiashuang Huang , Hengrong Ju , Tianyi Zhou , Weiping Ding

For predicting cancer survival outcomes, standard approaches in clinical research are often based on two main modalities: pathology images for observing cell morphology features, and genomic (e.g., bulk RNA-seq) for quantifying gene…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hongxiao Wang , Yang Yang , Zhuo Zhao , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Accurate survival prediction is essential for personalised cancer treatment. We propose ModalSurv, a multimodal deep survival framework integrating clinical, MRI, histopathology, and RNA-sequencing data via modality-specific projections and…

Machine Learning · Computer Science 2025-12-19 Noorul Wahab , Ethar Alzaid , Jiaqi Lv , Fayyaz Minhas , Adam Shephard , Shan E Ahmed Raza

Conditional random field (CRF) and Structural Support Vector Machine (Structural SVM) are two state-of-the-art methods for structured prediction which captures the interdependencies among output variables. The success of these methods is…

Machine Learning · Computer Science 2015-03-19 Qi Mao , Ivor W. Tsang

Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for portal hypertension, but provides variable survival outcomes and frequent overt hepatic encephalopathy (OHE), indicating the necessity of accurate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Junhao Dong , Dejia Liu , Ruiqi Ding , Zongxing Chen , Yingjie Huang , Zhu Meng , Jianbo Zhao , Zhicheng Zhao , Fei Su

Sudden Unexpected Death in Epilepsy (SUDEP) and acute ischemic stroke are life-threatening conditions involving complex interactions across cortical, brainstem, and autonomic systems. We present a unified geometric-stochastic multimodal…

Machine Learning · Computer Science 2025-12-10 Preksha Girish , Rachana Mysore , Mahanthesha U , Shrey Kumar , Misbah Fatimah Annigeri , Tanish Jain

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Richard J. Chen , Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Jana Lipkova , Muhammad Shaban , Maha Shady , Mane Williams , Bumjin Joo , Zahra Noor , Faisal Mahmood

Effectively medication recommendation with complex multimorbidity conditions is a critical task in healthcare. Most existing works predicted medications based on longitudinal records, which assumed the information transmitted patterns of…

Machine Learning · Computer Science 2023-09-13 Sicen Liu , Xiaolong Wang , JIngcheng Du , Yongshuai Hou , Xianbing Zhao , Hui Xu , Hui Wang , Yang Xiang , Buzhou Tang

Cancer survival prediction using multi-modal medical imaging presents a critical challenge in oncology, mainly due to the vulnerability of deep learning models to noise and protocol variations across imaging centers. Current approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Aiman Farooq , Azad Singh , Deepak Mishra , Santanu Chaudhury

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Multi-modal learning that combines pathological images with genomic data has significantly enhanced the accuracy of survival prediction. Nevertheless, existing methods have not fully utilized the inherent hierarchical structure within both…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Ying Chen , Jiajing Xie , Yuxiang Lin , Yuhang Song , Wenxian Yang , Rongshan Yu

Single-cell gene expression measurements encode variability spanning molecular noise, cell-to-cell heterogeneity, and technical artifacts. Mechanistic stochastic models provide powerful approaches to disentangle these sources, yet inferring…

Quantitative Methods · Quantitative Biology 2025-09-19 Christopher E. Miles

Textual passwords remain a predominant authentication mechanism in web security. To evaluate their strength, existing research has proposed several data-driven models across various scenarios. However, these models generally treat passwords…

Cryptography and Security · Computer Science 2025-09-23 Mingjian Duan , Ming Xu , Shenghao Zhang , Jiaheng Zhang , Weili Han

In healthcare applications, temporal variables that encode movement, health status and longitudinal patient evolution are often accompanied by rich structured information such as demographics, diagnostics and medical exam data. However,…

Deep learning has shown strong potential in cancer classification from whole-slide images (WSIs), but the need for extensive expert annotations often limits its success. Annotation-free approaches, such as multiple instance learning (MIL)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Willmer Rafell Quinones Robles , Sakonporn Noree , Jongwoo Kim , Young Sin Ko , Bryan Wong , Mun Yong Yi

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

A comprehensive and reliable survival prediction model is of great importance to assist in the personalized management of Head and Neck Cancer (HNC) patients treated with curative Radiation Therapy (RT). In this work, we propose IMLSP, an…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Meixu Chen , Kai Wang , Jing Wang