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Artificial intelligence (AI) is transforming materials science, enabling both theoretical advancements and accelerated materials discovery. Recent progress in crystal generation models, which design crystal structures for targeted…

Materials Science · Physics 2025-02-25 Zhuoyuan Li , Siyu Liu , Beilin Ye , David J. Srolovitz , Tongqi Wen

We propose Materealize, a multi-agent system for end-to-end inorganic materials design and synthesis that orchestrates core domain tools spanning structure generation, property prediction, synthesizability prediction, and synthesis planning…

Crystalline materials, with symmetrical and periodic structures, exhibit a wide spectrum of properties and have been widely used in numerous applications across electronics, energy, and beyond. For crystalline materials discovery,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-11 Zhenzhong Wang , Haowei Hua , Wanyu Lin , Ming Yang , Kay Chen Tan

Computational materials discovery relies on the generation of plausible crystal structures. The plausibility is typically judged through density functional theory methods which, while typically accurate at zero Kelvin, often favor…

Computational Engineering, Finance, and Science · Computer Science 2025-11-04 Thorben Prein , Willis O'Leary , Aikaterini Flessa Savvidou , Elchaïma Bourneix , Joonatan E. M. Laulainen

Designing inorganic crystalline materials with tailored properties is critical to technological innovation, yet current generative computational methods often struggle to efficiently explore desired targets with sufficient interpretability.…

Materials Science · Physics 2025-12-29 Izumi Takahara , Teruyasu Mizoguchi , Bang Liu

Diffusion-based deep generative models have emerged as powerful tools for inverse materials design. Yet, many existing approaches overlook essential chemical constraints such as oxidation state balance, which can lead to chemically invalid…

Materials Science · Physics 2025-07-29 Mouyang Cheng , Weiliang Luo , Hao Tang , Bowen Yu , Yongqiang Cheng , Weiwei Xie , Ju Li , Heather J. Kulik , Mingda Li

We have built an integrated computational platform for material properties at extreme conditions, ProME (Professional Materials at Extremes) v1.0, which enables integrated calculations for multicomponent alloys, covering high temperatures…

The constant demand for new functional materials calls for efficient strategies to accelerate the materials design and discovery. In addressing this challenge, machine learning generative models can offer promising opportunities since they…

Materials Science · Physics 2020-06-24 Sungwon Kim , Juhwan Noh , Geun Ho Gu , Alán Aspuru-Guzik , Yousung Jung

For a very long time, computational approaches to the design of new materials have relied on an iterative process of finding a candidate material and modeling its properties. AI has played a crucial role in this regard, helping to…

Crystal structure predictions based on the combination of first-principles calculations and machine learning have achieved significant success in materials science. However, most of these approaches are limited to predicting specific…

Materials Science · Physics 2025-01-28 Zongguo Wang , Ziyi Chen , Yang Yuan , Yangang Wang

Generative modeling has emerged as a promising approach for crystal structure discovery. However, existing LLM-based generative models struggle with low-level atomic precision, while diffusion-based methods fall short in integrating…

Artificial Intelligence · Computer Science 2026-05-18 Yuyang Wu , Stefano Falletta , Delia McGrath , Sherry Yang

Artificial Intelligence (AI) is redefining the frontiers of scientific domains, ranging from drug discovery to meteorological modeling, yet its integration within industrial manufacturing remains nascent and fraught with operational…

Computational Engineering, Finance, and Science · Computer Science 2025-11-18 Yingjie Shi , Yiru Gong , Yiqun Su , Suya Xiong , Jiale Han , Runtian Miao

Crystallisation is an important phenomenon which facilitates the purification as well as structural and bulk phase material characterisation using crystallographic methods. However, different conditions can lead to a vast set of different…

Robotics · Computer Science 2024-09-10 Edward C Lee , Daniel Salley , Abhishek Sharma , Leroy Cronin

Gradient-based methods offer a simple, efficient strategy for materials design by directly optimizing candidates using gradients from pretrained property predictors. However, their use in crystal structure optimization is hindered by two…

Materials Science · Physics 2025-05-30 Akihiro Fujii , Yoshitaka Ushiku , Koji Shimizu , Anh Khoa Augustin Lu , Satoshi Watanabe

In silico design and optimization of new materials primarily relies on high-accuracy atomic simulators that perform density functional theory (DFT) calculations. While recent works showcase the strong potential of machine learning to…

Machine Learning · Computer Science 2025-09-30 Prashant Govindarajan , Mathieu Reymond , Antoine Clavaud , Mariano Phielipp , Santiago Miret , Sarath Chandar

We introduce CrystalFormer, a transformer-based autoregressive model specifically designed for space group-controlled generation of crystalline materials. By explicitly incorporating space group symmetry, CrystalFormer greatly reduces the…

Materials Science · Physics 2025-09-29 Zhendong Cao , Xiaoshan Luo , Jian Lv , Lei Wang

Discovering materials with new structural chemistry is key to achieving transformative functionality. Generative artificial intelligence offers a scalable route to propose candidate crystal structures. We introduce a reliable low-cost proxy…

This paper presents the CRISTAL-iSE project as a framework for the management of provenance information in industry. The project itself is a research collaboration between academia and industry. A key factor in the project is the use of a…

The design of alloys is a multi-scale problem that requires a holistic approach that involves retrieving relevant knowledge, applying advanced computational methods, conducting experimental validations, and analyzing the results, a process…

Artificial Intelligence · Computer Science 2024-07-16 Alireza Ghafarollahi , Markus J. Buehler

As in many other fields, the rapid rise of generative artificial intelligence is reshaping materials discovery by offering new ways to propose crystal structures and, in some cases, even predict desired properties. This review provides a…

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