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Congenital heart disease (CHD) is a critical condition that demands early detection, particularly in infancy and childhood. This study presents a deep learning model designed to detect CHD using phonocardiogram (PCG) signals, with a focus…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-01 Abdul Jabbar , Ethan Grooby , Jack Crozier , Alexander Gallon , Vivian Pham , Khawza I Ahmad , Md Hassanuzzaman , Raqibul Mostafa , Ahsan H. Khandoker , Faezeh Marzbanrad

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to…

Myocardial infarction is a major cause of death globally, and accurate early diagnosis from electrocardiograms (ECGs) remains a clinical priority. Deep learning models have shown promise for automated ECG interpretation, but require large…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Lachin Naghashyar

Cardiac arrhythmias are a leading cause of life-threatening cardiac events, highlighting the urgent need for accurate and timely detection. Electrocardiography (ECG) remains the clinical gold standard for arrhythmia diagnosis; however,…

Machine Learning · Computer Science 2025-05-09 Zuraiz Baig , Sidra Nasir , Rizwan Ahmed Khan , Muhammad Zeeshan Ul Haque

Echocardiography (echo) is the first imaging modality used when assessing cardiac function. The measurement of functional biomarkers from echo relies upon the segmentation of cardiac structures and deep learning models have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Iman Islam , Esther Puyol-Antón , Bram Ruijsink , Andrew J. Reader , Andrew P. King

Diabetes has a long asymptomatic period which can often remain undiagnosed for multiple years. In this study, we trained a deep learning model to detect new-onset diabetes using 12-lead ECG and readily available demographic information. To…

Machine Learning · Computer Science 2025-12-01 Hao Zhang , Neil Jethani , Aahlad Puli , Leonid Garber , Lior Jankelson , Yindalon Aphinyanaphongs , Rajesh Ranganath

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

While deep learning has shown promise in improving the automated diagnosis of disease based on chest X-rays, deep networks may exhibit undesirable behavior related to shortcuts. This paper studies the case of spurious class skew in which…

Computer Vision and Pattern Recognition · Computer Science 2020-09-23 Sarah Jabbour , David Fouhey , Ella Kazerooni , Michael W. Sjoding , Jenna Wiens

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Continuous monitoring of cardiac activity is paramount to understanding the functioning of the heart in addition to identifying precursors to conditions such as Atrial Fibrillation. Through continuous cardiac monitoring, early indications…

Machine Learning · Computer Science 2020-10-13 Prithvi Suresh , Naveen Narayanan , Chakilam Vijay Pranav , Vineeth Vijayaraghavan

The analysis of electrocardiogram (ECG) signals can be time consuming as it is performed manually by cardiologists. Therefore, automation through machine learning (ML) classification is being increasingly proposed which would allow ML…

Machine Learning · Computer Science 2022-05-10 Shourya Verma

Subgroup selection in clinical trials is essential for identifying patient groups that react differently to a treatment, thereby enabling personalised medicine. In particular, subgroup selection can identify patient groups that respond…

ECG heartbeat classification plays a vital role in diagnosis of cardiac arrhythmia. The goal of the Physionet/CinC 2021 challenge was to accurately classify clinical diagnosis based on 12, 6, 4, 3 or 2-lead ECG recordings in order to aid…

The electrocardiogram (ECG) is routinely used in hospitals to analyze cardiovascular status and health of an individual. Abnormal heart rhythms can be a precursor to more serious conditions including sudden cardiac death. Classifying…

Signal Processing · Electrical Eng. & Systems 2022-07-15 Neville D. Gai

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

Other Quantitative Biology · Quantitative Biology 2025-10-20 Syed Ibad Hasnain

Deep learning-based image segmentation has allowed for the fully automated, accurate, and rapid analysis of musculoskeletal (MSK) structures from medical images. However, current approaches were either applied only to 2D cross-sectional…

An increasing number of reports raise concerns about the risk that machine learning algorithms could amplify health disparities due to biases embedded in the training data. Seyyed-Kalantari et al. find that models trained on three chest…

Artificial Intelligence · Computer Science 2023-07-07 Mélanie Bernhardt , Charles Jones , Ben Glocker

Analysing electrocardiograms (ECGs) is an inexpensive and non-invasive, yet powerful way to diagnose heart disease. ECG studies using Machine Learning to automatically detect abnormal heartbeats so far depend on large, manually annotated…

Signal Processing · Electrical Eng. & Systems 2022-01-11 Mononito Goswami , Benedikt Boecking , Artur Dubrawski

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Non-significant randomized control trials can hide subgroups of good responders to experimental drugs, thus hindering subsequent development. Identifying such heterogeneous treatment effects is key for precision medicine and many post-hoc…

Methodology · Statistics 2024-01-24 Valentine Perrin , Nathan Noiry , Nicolas Loiseau , Alex Nowak