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Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

In this survey, we introduce Meta-Black-Box-Optimization~(MetaBBO) as an emerging avenue within the Evolutionary Computation~(EC) community, which incorporates Meta-learning approaches to assist automated algorithm design. Despite the…

Neural and Evolutionary Computing · Computer Science 2025-05-01 Zeyuan Ma , Hongshu Guo , Yue-Jiao Gong , Jun Zhang , Kay Chen Tan

Designing and implementing explainable systems is seen as the next step towards increasing user trust in, acceptance of and reliance on Artificial Intelligence (AI) systems. While explaining choices made by black-box algorithms such as…

Multiagent Systems · Computer Science 2022-08-23 Sharadhi Alape Suryanarayana , David Sarne , Sarit Kraus

Black box systems for automated decision making, often based on machine learning over (big) data, map a user's features into a class or a score without exposing the reasons why. This is problematic not only for lack of transparency, but…

Artificial Intelligence · Computer Science 2018-06-27 Dino Pedreschi , Fosca Giannotti , Riccardo Guidotti , Anna Monreale , Luca Pappalardo , Salvatore Ruggieri , Franco Turini

Algorithm fairness has become a central problem for the broad adoption of artificial intelligence. Although the past decade has witnessed an explosion of excellent work studying algorithm biases, achieving fairness in real-world AI…

Machine Learning · Computer Science 2023-09-06 James Enouen , Tianshu Sun , Yan Liu

We propose a general model explanation system (MES) for "explaining" the output of black box classifiers. This paper describes extensions to Turner (2015), which is referred to frequently in the text. We use the motivating example of a…

Machine Learning · Statistics 2016-07-01 Ryan Turner

Many of the computing systems programmed using Machine Learning are opaque: it is difficult to know why they do what they do or how they work. The Explainable Artificial Intelligence research program aims to develop analytic techniques with…

General Literature · Computer Science 2019-07-08 Carlos Zednik

The field of machine learning has seen tremendous progress in recent years, with deep learning models delivering exceptional performance across a range of tasks. However, these models often come at the cost of interpretability, as they…

Machine Learning · Computer Science 2024-01-08 Shun Liu

Large Language Models (LLMs) exhibit remarkable capabilities across a spectrum of tasks in financial services, including report generation, chatbots, sentiment analysis, regulatory compliance, investment advisory, financial knowledge…

Computational Engineering, Finance, and Science · Computer Science 2025-06-02 Hariom Tatsat , Ariye Shater

There is a long history in machine learning of model ensembling, beginning with boosting and bagging and continuing to the present day. Much of this history has focused on combining models for classification and regression, but recently…

Machine Learning · Computer Science 2024-05-28 Ira Globus-Harris , Varun Gupta , Michael Kearns , Aaron Roth

Machines are being increasingly used in decision-making processes, resulting in the realization that decisions need explanations. Unfortunately, an increasing number of these deployed models are of a 'black-box' nature where the reasoning…

Artificial Intelligence · Computer Science 2023-11-07 Sopam Dasgupta

The implementation of Artificial Intelligence (AI) systems in the manufacturing domain enables higher production efficiency, outstanding performance, and safer operations, leveraging powerful tools such as deep learning and reinforcement…

Artificial Intelligence · Computer Science 2021-07-07 Georgios Sofianidis , Jože M. Rožanec , Dunja Mladenić , Dimosthenis Kyriazis

Machine learning accelerates molecular property prediction, yet state-of-the-art Large Language Models and Graph Neural Networks operate as black boxes. In drug discovery, where safety is critical, this opacity risks masking false…

Machine Learning · Computer Science 2026-03-03 Oscar Rivera , Ziqing Wang , Matthieu Dagommer , Abhishek Pandey , Kaize Ding

Achieving human-level performance on some of Machine Reading Comprehension (MRC) datasets is no longer challenging with the help of powerful Pre-trained Language Models (PLMs). However, it is necessary to provide both answer prediction and…

Computation and Language · Computer Science 2022-04-29 Yiming Cui , Ting Liu , Wanxiang Che , Zhigang Chen , Shijin Wang

Recent advances in deep learning have led to increasingly complex models with deeper layers and more parameters, reducing interpretability and making their decisions harder to understand. While many methods explain black-box reasoning, most…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Nuoye Xiong , Anqi Dong , Ning Wang , Cong Hua , Guangming Zhu , Lin Mei , Peiyi Shen , Liang Zhang

Interpretable machine learning has become a strong competitor for traditional black-box models. However, the possible loss of the predictive performance for gaining interpretability is often inevitable, putting practitioners in a dilemma of…

Machine Learning · Computer Science 2019-05-13 Tong Wang , Qihang Lin

In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

Complex black-box predictive models may have high performance, but lack of interpretability causes problems like lack of trust, lack of stability, sensitivity to concept drift. On the other hand, achieving satisfactory accuracy of…

Machine Learning · Computer Science 2020-02-12 Alicja Gosiewska , Przemyslaw Biecek

Unlike classical lexical overlap metrics such as BLEU, most current evaluation metrics for machine translation (for example, COMET or BERTScore) are based on black-box large language models. They often achieve strong correlations with human…

Computation and Language · Computer Science 2024-11-19 Christoph Leiter , Piyawat Lertvittayakumjorn , Marina Fomicheva , Wei Zhao , Yang Gao , Steffen Eger

Traditional machine learning models often prioritize predictive accuracy, often at the expense of model transparency and interpretability. The lack of transparency makes it difficult for organizations to comply with regulatory requirements…

Machine Learning · Computer Science 2025-05-16 Fahad Almalki , Mehedi Masud
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