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The scarcity of annotated data has sparked significant interest in unsupervised pre-training methods that leverage medical reports as auxiliary signals for medical visual representation learning. However, existing research overlooks the…
The discovery of anticancer therapeutics has traditionally treated organic small molecules and metal-based coordination complexes as separate chemical domains, limiting knowledge transfer despite their shared biological objectives. This…
Identifying enzymes that catalyze target biochemical reactions is a key step in computational enzyme discovery and biocatalyst design. Recent representation-learning methods formulate this problem as enzyme--reaction matching, where paired…
Predicting enzyme kinetic parameters quantifies how efficiently an enzyme catalyzes a specific substrate under defined biochemical conditions. Canonical parameters such as the turnover number ($k_\text{cat}$), Michaelis constant…
Kinetic parameters such as the turnover number ($k_{cat}$) and Michaelis constant ($K_{\mathrm{M}}$) are essential for modelling enzymatic activity but experimental data remains limited in scale and diversity. Previous methods for…
Existing vision-text contrastive learning like CLIP aims to match the paired image and caption embeddings while pushing others apart, which improves representation transferability and supports zero-shot prediction. However, medical…
Virtual screening, which identifies potential drugs from vast compound databases to bind with a particular protein pocket, is a critical step in AI-assisted drug discovery. Traditional docking methods are highly time-consuming, and can only…
Recent advances in brain-inspired artificial intelligence have sought to align neural signals with visual semantics using multimodal models such as CLIP. However, existing methods often treat CLIP as a static feature extractor, overlooking…
Conventional object detectors rely on cross-entropy classification, which can be vulnerable to class imbalance and label noise. We propose CLIP-Joint-Detect, a simple and detector-agnostic framework that integrates CLIP-style contrastive…
Large-scale multi-modal contrastive pre-training has demonstrated great utility to learn transferable features for a range of downstream tasks by mapping multiple modalities into a shared embedding space. Typically, this has employed…
Contrastive learning has emerged as a transformative method for learning effective visual representations through the alignment of image and text embeddings. However, pairwise similarity computation in contrastive loss between image and…
Recent advancements in image-text matching have been notable, yet prevailing models predominantly cater to broad queries and struggle with accommodating fine-grained query intention. In this paper, we work towards the…
Contrastive vision-language models continue to be the dominant approach for image and text retrieval. Contrastive Language-Image Pre-training (CLIP) trains two neural networks in contrastive manner to align their image and text embeddings…
Virtual screening aims to efficiently identify active ligands from massive chemical libraries for a given target pocket. Recent CLIP-style models such as DrugCLIP enable scalable virtual screening by embedding pockets and ligands into a…
Multimodal search has revolutionized the fashion industry, providing a seamless and intuitive way for users to discover and explore fashion items. Based on their preferences, style, or specific attributes, users can search for products by…
Contrastive Language-Image Pre-training (CLIP) has become a foundation model and has been applied to various vision and multimodal tasks. However, recent works indicate that CLIP falls short in distinguishing detailed differences in images…
We introduce eCLIP, an enhanced version of the CLIP model that integrates expert annotations in the form of radiologist eye-gaze heatmaps. It tackles key challenges in contrastive multi-modal medical imaging analysis, notably data scarcity…
Contrastive Language-Image Pre-training (CLIP) has been shown to improve zero-shot generalization capabilities of language and vision models. In this paper, we extend CLIP for efficient knowledge distillation, by utilizing embeddings as…
Recent advances in contrastive representation learning over paired image-text data have led to models such as CLIP that achieve state-of-the-art performance for zero-shot classification and distributional robustness. Such models typically…
Most video-and-language representation learning approaches employ contrastive learning, e.g., CLIP, to project the video and text features into a common latent space according to the semantic similarities of text-video pairs. However, such…