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Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction…

Genomics · Quantitative Biology 2024-05-21 Jiayu Shang , Cheng Peng , Yongxin Ji , Jiaojiao Guan , Dehan Cai , Xubo Tang , Yanni Sun

Foundation models are rapidly being developed for computational pathology applications. However, it remains an open question which factors are most important for downstream performance with data scale and diversity, model size, and training…

Deep learning has contributed greatly to many successes in artificial intelligence in recent years. Today, it is possible to train models that have thousands of layers and hundreds of billions of parameters. Large-scale deep models have…

Machine Learning · Computer Science 2023-02-15 Konrad Zuchniak

Model distillation enables the transfer of knowledge from large-scale models to compact student models, facilitating deployment in resource-constrained environments. However, conventional distillation approaches often suffer from…

Machine Learning · Computer Science 2025-08-21 Suleyman Olcay Polat , Poli A. Nemkova , Mark V. Albert

Even though deep speaker models have demonstrated impressive accuracy in speaker verification tasks, this often comes at the expense of increased model size and computation time, presenting challenges for deployment in resource-constrained…

Sound · Computer Science 2023-12-21 Xuechen Liu , Md Sahidullah , Tomi Kinnunen

The extensive amounts of data required for training deep neural networks pose significant challenges on storage and transmission fronts. Dataset distillation has emerged as a promising technique to condense the information of massive…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Ali Abbasi , Ashkan Shahbazi , Hamed Pirsiavash , Soheil Kolouri

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

Dataset distillation aims to distill the knowledge of a large-scale real dataset into small yet informative synthetic data such that a model trained on it performs as well as a model trained on the full dataset. Despite recent progress,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Ahmad Sajedi , Samir Khaki , Lucy Z. Liu , Ehsan Amjadian , Yuri A. Lawryshyn , Konstantinos N. Plataniotis

Sampling from pretrained diffusion and flow-matching models typically requires many forward passes to generate diverse and high-fidelity images. Existing distillation methods often rely on multiple auxiliary networks, carefully designed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Yuan Zhang , Chenyi Li , Guoqing Ma , Jiajun Zha , Yuanming Yang , Bo Wang , Wei Tang , Wenbo Li , Haoyang Huang , Nan Duan

Pre-trained language models (PLMs) achieve great success in NLP. However, their huge model sizes hinder their applications in many practical systems. Knowledge distillation is a popular technique to compress PLMs, which learns a small…

Computation and Language · Computer Science 2021-06-03 Chuhan Wu , Fangzhao Wu , Yongfeng Huang

With numerous medical tasks, the performance of deep models has recently experienced considerable improvements. These models are often adept learners. Yet, their intricate architectural design and high computational complexity make…

Image and Video Processing · Electrical Eng. & Systems 2023-03-17 Eddardaa Ben Loussaief , Hatem Rashwan , Mohammed Ayad , Mohammed Zakaria Hassan , Domenec Puig

Pre-trained language models such as BERT have proven to be highly effective for natural language processing (NLP) tasks. However, the high demand for computing resources in training such models hinders their application in practice. In…

Computation and Language · Computer Science 2019-08-27 Siqi Sun , Yu Cheng , Zhe Gan , Jingjing Liu

Casting complex inputs into tractable representations is a critical step across various fields. Diverse embedding models emerge from differences in architectures, loss functions, input modalities and datasets, each capturing unique aspects…

Machine-learned interatomic potentials have transformed computational research in the physical sciences. Recent atomistic `foundation' models have changed the field yet again: trained on many different chemical elements and domains, these…

Knowledge distillation involves transferring the predictive capabilities of large, high-performing AI models (teachers) to smaller models (students) that can operate in environments with limited computing power. In this paper, we address…

Machine Learning · Computer Science 2026-01-12 Pattarawat Chormai , Ali Hashemi , Klaus-Robert Müller , Grégoire Montavon

Modeling physical systems in a generative manner offers several advantages, including the ability to handle partial observations, generate diverse solutions, and address both forward and inverse problems. Recently, diffusion models have…

Machine Learning · Computer Science 2025-05-29 Yi Zhang , Difan Zou

Diffusion Models (DMs), also referred to as score-based diffusion models, utilize neural networks to specify score functions. Unlike most other probabilistic models, DMs directly model the score functions, which makes them more flexible to…

Machine Learning · Computer Science 2023-04-11 Weijian Luo

Embeddings from Large Language Models (LLMs) have emerged as critical components in various applications, particularly for information retrieval. While high-dimensional embeddings generally demonstrate superior performance as they contain…

Computation and Language · Computer Science 2024-07-31 Jinsung Yoon , Raj Sinha , Sercan O Arik , Tomas Pfister

Foundation models for medical imaging demonstrate superior generalization capabilities across diverse anatomical structures and clinical applications. Their outstanding performance relies on substantial computational resources, limiting…

Image and Video Processing · Electrical Eng. & Systems 2026-04-15 Chen Ma , Jing Jiao , Shuyu Liang , Junhu Fu , Qin Wang , Zeju Li , Yuanyuan Wang , Yi Guo

In natural language processing (NLP) tasks, slow inference speed and huge footprints in GPU usage remain the bottleneck of applying pre-trained deep models in production. As a popular method for model compression, knowledge distillation…

Computation and Language · Computer Science 2020-12-15 Fei Yuan , Linjun Shou , Jian Pei , Wutao Lin , Ming Gong , Yan Fu , Daxin Jiang