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Proteins are macromolecules that perform essential functions in all living organisms. Designing novel proteins with specific structures and desired functions has been a long-standing challenge in the field of bioengineering. Existing…

Biomolecules · Quantitative Biology 2023-03-03 Chence Shi , Chuanrui Wang , Jiarui Lu , Bozitao Zhong , Jian Tang

Deep learning has revolutionized medical image analysis, playing a vital role in modern clinical applications. However, the deployment of large-scale models in real-world clinical settings remains challenging due to high computational…

Machine Learning · Computer Science 2026-02-03 Cuong Manh Nguyen , Truong-Son Hy

Embedding techniques have become essential components of large databases in the deep learning era. By encoding discrete entities, such as words, items, or graph nodes, into continuous vector spaces, embeddings facilitate more efficient…

Information Retrieval · Computer Science 2024-10-18 Shiwei Li , Zhuoqi Hu , Xing Tang , Haozhao Wang , Shijie Xu , Weihong Luo , Yuhua Li , Xiuqiang He , Ruixuan Li

The rapid advancements in artificial intelligence (AI) have revolutionized smart healthcare, driving innovations in wearable technologies, continuous monitoring devices, and intelligent diagnostic systems. However, security, explainability,…

Machine Learning · Computer Science 2024-10-02 Prasenjit Maji , Amit Kumar Mondal , Hemanta Kumar Mondal , Saraju P. Mohanty

Discovering patterns in data that best describe the differences between classes allows to hypothesize and reason about class-specific mechanisms. In molecular biology, for example, this bears promise of advancing the understanding of…

Machine Learning · Computer Science 2023-12-08 Nils Philipp Walter , Jonas Fischer , Jilles Vreeken

This study investigates the key characteristics and suitability of widely used Facial Expression Recognition (FER) datasets for training deep learning models. In the field of affective computing, FER is essential for interpreting human…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 F. Xavier Gaya-Morey , Cristina Manresa-Yee , Célia Martinie , Jose M. Buades-Rubio

The precise categorization of white blood cell (WBC) is crucial for diagnosing blood-related disorders. However, manual analysis in clinical settings is time-consuming, labor-intensive, and prone to errors. Numerous studies have employed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Yuzhuo Chen , Zetong Chen , Yunuo An , Chenyang Lu , Xu Qiao

Facial expression classification remains a challenging task due to the high dimensionality and inherent complexity of facial image data. This paper presents Hy-Facial, a hybrid feature extraction framework that integrates both deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Xinjin Li , Yu Ma , Kaisen Ye , Jinghan Cao , Minghao Zhou , Yeyang Zhou

In software, a vulnerability is a defect in a program that attackers might utilize to acquire unauthorized access, alter system functions, and acquire information. These vulnerabilities arise from programming faults, design flaws, incorrect…

Software Engineering · Computer Science 2024-11-28 Md. Fahim Sultan , Tasmin Karim , Md. Shazzad Hossain Shaon , Mohammad Wardat , Mst Shapna Akter

In this paper, we present a novel approach to accelerate the Bayesian inference process, focusing specifically on the nested sampling algorithms. Bayesian inference plays a crucial role in cosmological parameter estimation, providing a…

Instrumentation and Methods for Astrophysics · Physics 2024-10-17 Isidro Gómez-Vargas , J. Alberto Vázquez

Tabular data learning has extensive applications in deep learning but its existing embedding techniques are limited in numerical and categorical features such as the inability to capture complex relationships and engineering. This paper…

Machine Learning · Computer Science 2024-09-02 Yuqian Wu , Hengyi Luo , Raymond S. T. Lee

Machine learning models are widely integrated into modern mobile apps to analyze user behaviors and deliver personalized services. Ensuring low-latency on-device model execution is critical for maintaining high-quality user experiences.…

Machine Learning · Computer Science 2026-03-24 Chen Gong , Zhenzhe Zheng , Yiliu Chen , Sheng Wang , Fan Wu , Guihai Chen

A unique challenge in predictive model building for omics data has been the small number of samples $(n)$ versus the large amount of features $(p)$. This "$n\ll p$" property brings difficulties for disease outcome classification using deep…

Machine Learning · Statistics 2019-05-27 Yunchuan Kong , Tianwei Yu

In recent years, deep learning techniques have made significant strides in molecular generation for specific targets, driving advancements in drug discovery. However, existing molecular generation methods present significant limitations:…

Machine Learning · Computer Science 2025-03-12 Taojie Kuang , Qianli Ma , Athanasios V. Vasilakos , Yu Wang , Qiang , Cheng , Zhixiang Ren

Deep learning architectures have proved versatile in a number of drug discovery applications, including the modelling of in vitro compound activity. While controlling for prediction confidence is essential to increase the trust,…

Machine Learning · Computer Science 2018-10-23 Isidro Cortes-Ciriano , Andreas Bender

Transfer learning has become an essential tool in modern computer vision, allowing practitioners to leverage backbones, pretrained on large datasets, to train successful models from limited annotated data. Choosing the right backbone is…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Joris Guerin , Shray Bansal , Amirreza Shaban , Paulo Mann , Harshvardhan Gazula

Paper-intensive industries like insurance, law, and government have long leveraged optical character recognition (OCR) to automatically transcribe hordes of scanned documents into text strings for downstream processing. Even in 2019, there…

Computer Vision and Pattern Recognition · Computer Science 2020-01-17 W. Ronny Huang , Yike Qi , Qianqian Li , Jonathan Degange

In most gene expression data, the number of training samples is very small compared to the large number of genes involved in the experiments. However, among the large amount of genes, only a small fraction is effective for performing a…

Machine Learning · Computer Science 2013-06-07 T. Chandrasekhar , K. Thangavel , E. N. Sathishkumar

Facial biometrics has been recently received tremendous attention as a convenient replacement for traditional authentication systems. Consequently, detecting malicious attempts has found great significance, leading to extensive studies in…

Computer Vision and Pattern Recognition · Computer Science 2022-01-03 Arian Sabaghi , Marzieh Oghbaie , Kooshan Hashemifard , Mohammad Akbari

One of the main computational bottlenecks when working with kernel based learning is dealing with the large and typically dense kernel matrix. Techniques dealing with fast approximations of the matrix vector product for these kernel…

Machine Learning · Computer Science 2024-04-29 Theresa Wagner , Franziska Nestler , Martin Stoll