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Protein representation learning plays a crucial role in understanding the structure and function of proteins, which are essential biomolecules involved in various biological processes. In recent years, deep learning has emerged as a…

Biomolecules · Quantitative Biology 2024-03-11 Bozhen Hu , Cheng Tan , Lirong Wu , Jiangbin Zheng , Jun Xia , Zhangyang Gao , Zicheng Liu , Fandi Wu , Guijun Zhang , Stan Z. Li

Amino acid sequence portrays most intrinsic form of a protein and expresses primary structure of protein. The order of amino acids in a sequence enables a protein to acquire a particular stable conformation that is responsible for the…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , David Fernandez-Baca , Akshay Deepak , Sudhakar Tripathi

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

Cross-domain few-shot learning (CDFSL) addresses learning problems where knowledge needs to be transferred from one or more source domains into an instance-scarce target domain with an explicitly different distribution. Recently published…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Hongyu Wang , Eibe Frank , Bernhard Pfahringer , Michael Mayo , Geoffrey Holmes

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Identifying anomalies has become one of the primary strategies towards security and protection procedures in computer networks. In this context, machine learning-based methods emerge as an elegant solution to identify such scenarios and…

Machine Learning · Computer Science 2022-12-07 Lucas Biaggi , João P. Papa , Kelton A. P Costa , Danillo R. Pereira , Leandro A. Passos

Deep learning has significantly advanced automatic medical diagnostics and released the occupation of human resources to reduce clinical pressure, yet the persistent challenge of data scarcity in this area hampers its further improvements…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Zehui Zhao , Laith Alzubaidi , Jinglan Zhang , Ye Duan , Usman Naseem , Yuantong Gu

Traditional neuroimage analysis pipelines involve computationally intensive, time-consuming optimization steps, and thus, do not scale well to large cohort studies with thousands or tens of thousands of individuals. In this work we propose…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Leonie Henschel , Sailesh Conjeti , Santiago Estrada , Kersten Diers , Bruce Fischl , Martin Reuter

Image classification serves as the cornerstone of computer vision, traditionally achieved through discriminative models based on deep neural networks. Recent advancements have introduced classification methods derived from generative…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Chunxiao Li , Xiaoxiao Wang , Boming Miao , Chuanlong Xie , Zizhe Wang , Yao Zhu

Deep learning techniques have considerably improved speech processing in recent years. Speaker representations extracted by deep learning models are being used in a wide range of tasks such as speaker recognition and speech emotion…

Audio and Speech Processing · Electrical Eng. & Systems 2023-01-25 Amirhossein Hajavi , Ali Etemad

Biological data including gene expression data are generally high-dimensional and require efficient, generalizable, and scalable machine-learning methods to discover their complex nonlinear patterns. The recent advances in machine learning…

Machine Learning · Computer Science 2020-12-21 Dinesh Singh , Héctor Climente-González , Mathis Petrovich , Eiryo Kawakami , Makoto Yamada

Genetic variants (GVs) are defined as differences in the DNA sequences among individuals and play a crucial role in diagnosing and treating genetic diseases. The rapid decrease in next generation sequencing cost has led to an exponential…

Machine Learning · Computer Science 2024-12-06 Zehui Li , Vallijah Subasri , Guy-Bart Stan , Yiren Zhao , Bo Wang

Feature selection is a crucial step in developing robust and powerful machine learning models. Feature selection techniques can be divided into two categories: filter and wrapper methods. While wrapper methods commonly result in strong…

Machine Learning · Computer Science 2022-07-07 Jarne Verhaeghe , Jeroen Van Der Donckt , Femke Ongenae , Sofie Van Hoecke

This paper presents a novel, fast and privacy preserving implementation of deep autoencoders. DAEF (Deep Autoencoder for Federated learning), unlike traditional neural networks, trains a deep autoencoder network in a non-iterative way,…

Machine Learning · Computer Science 2023-07-19 David Novoa-Paradela , Oscar Romero-Fontenla , Bertha Guijarro-Berdiñas

Recent feature matching methods have achieved remarkable performance but lack efficiency consideration. In this paper, we revisit the mainstream detector-free matching pipeline and improve all its stages considering both accuracy and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Xi Li , Tong Rao , Cihui Pan

Deep learning-based vulnerability detection has shown great performance and, in some studies, outperformed static analysis tools. However, the highest-performing approaches use token-based transformer models, which are not the most…

Software Engineering · Computer Science 2023-10-03 Benjamin Steenhoek , Hongyang Gao , Wei Le

In this paper, we present Deep Extreme Feature Extraction (DEFE), a new ensemble MVA method for searching $\tau^{+}\tau^{-}$ channel of Higgs bosons in high energy physics. DEFE can be viewed as a deep ensemble learning scheme that trains a…

Machine Learning · Computer Science 2016-03-25 Chao Ma , Tianchenghou , Bin Lan , Jinhui Xu , Zhenhua Zhang

Deep Learning models have transformed various domains, including the healthcare sector, particularly biomedical image classification by learning intricate features and enabling accurate diagnostics pertaining to complex diseases. Recent…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Imran Ashraf , Mukhtar Ullah , Muhammad Faisal Nadeem , Muhammad Nouman Noor

As a fundamental task in natural language processing, word embedding converts each word into a representation in a vector space. A challenge with word embedding is that as the vocabulary grows, the vector space's dimension increases, which…

Computation and Language · Computer Science 2024-11-05 Jintang Xue , Yun-Cheng Wang , Chengwei Wei , C. -C. Jay Kuo
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