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In this paper we propose Structuring AutoEncoders (SAE). SAEs are neural networks which learn a low dimensional representation of data which are additionally enriched with a desired structure in this low dimensional space. While traditional…

Machine Learning · Computer Science 2019-08-20 Marco Rudolph , Bastian Wandt , Bodo Rosenhahn

Scientific archives now contain hundreds of petabytes of data across genomics, ecology, climate, and molecular biology that could reveal undiscovered patterns if systematically analyzed at scale. Large-scale, weakly-supervised datasets in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Samuel Stevens , Jacob Beattie , Tanya Berger-Wolf , Yu Su

Developing effective representations of protein structures is essential for advancing protein science, particularly for protein generative modeling. Current approaches often grapple with the complexities of the SE(3) manifold, rely on…

Machine Learning · Computer Science 2025-10-14 Shaoning Li , Le Zhuo , Yusong Wang , Mingyu Li , Xinheng He , Fandi Wu , Hongsheng Li , Pheng-Ann Heng

Sparse Autoencoders (SAEs) have emerged as a promising approach for interpreting neural network representations by learning sparse, human-interpretable features from dense activations. We investigate whether incorporating variational…

Machine Learning · Computer Science 2025-10-03 Zachary Baker , Yuxiao Li

Sparse Autoencoders (SAEs) are a promising approach for extracting neural network representations by learning a sparse and overcomplete decomposition of the network's internal activations. However, SAEs are traditionally trained considering…

Machine Learning · Computer Science 2025-04-02 Jeffrey Olmo , Jared Wilson , Max Forsey , Bryce Hepner , Thomas Vin Howe , David Wingate

Interpretability can improve the safety, transparency and trust of AI models, which is especially important in healthcare applications where decisions often carry significant consequences. Mechanistic interpretability, particularly through…

Text-to-image diffusion models generate images through an iterative denoising process, so internal neural layers produce trajectories of activations rather than single static representations. Sparse autoencoders (SAEs) have recently been…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Calvin Yeung , Prathyush Poduval , Ali Zakeri , Zhuowen Zou , Mohsen Imani

Sparse Autoencoders (SAEs) are increasingly used to interpret foundation models, but their role as an actionable intervention space remains less understood, especially in vision. We study whether sparse visual features can be used not only…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Gerasimos Chatzoudis , Zhuowei Li , Gemma E. Moran , Hao Wang , Dimitris N. Metaxas

Sparse Autoencoders (SAEs) provide potentials for uncovering structured, human-interpretable representations in Large Language Models (LLMs), making them a crucial tool for transparent and controllable AI systems. We systematically analyze…

Machine Learning · Computer Science 2026-02-03 Jack Gallifant , Shan Chen , Kuleen Sasse , Hugo Aerts , Thomas Hartvigsen , Danielle S. Bitterman

Sparse autoencoders (SAEs) are a useful tool for uncovering human-interpretable features in the activations of large language models (LLMs). While some expect SAEs to find the true underlying features used by a model, our research shows…

Machine Learning · Computer Science 2025-01-31 Gonçalo Paulo , Nora Belrose

Sparse Autoencoders (SAEs) are widely used to interpret neural networks by identifying meaningful concepts from their representations. However, do SAEs truly uncover all concepts a model relies on, or are they inherently biased toward…

Machine Learning · Computer Science 2025-12-03 Sai Sumedh R. Hindupur , Ekdeep Singh Lubana , Thomas Fel , Demba Ba

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but controlling their behavior reliably remains challenging, especially in open-ended generation settings. This paper…

Computation and Language · Computer Science 2025-12-08 Zirui He , Mingyu Jin , Bo Shen , Ali Payani , Yongfeng Zhang , Mengnan Du

Sparse Autoencoders (SAEs) have emerged as a promising solution for decomposing large language model representations into interpretable features. However, Paulo and Belrose (2025) have highlighted instability across different initialization…

Machine Learning · Computer Science 2025-06-24 Seonglae Cho , Harryn Oh , Donghyun Lee , Luis Eduardo Rodrigues Vieira , Andrew Bermingham , Ziad El Sayed

Audio pretrained models are widely employed to solve various tasks in speech processing, sound event detection, or music information retrieval. However, the representations learned by these models are unclear, and their analysis mainly…

Predicting protein function from amino acid sequence remains a central challenge in data-scarce (low-$N$) regimes, limiting machine learning-guided protein design when only small amounts of assay-labeled sequence-function data are…

Machine Learning · Computer Science 2025-08-27 Darin Tsui , Kunal Talreja , Amirali Aghazadeh

The fidelity with which neural networks can now generate content such as music presents a scientific opportunity: these systems appear to have learned implicit theories of such content's structure through statistical learning alone. This…

Sound · Computer Science 2026-03-03 Nikhil Singh , Manuel Cherep , Pattie Maes

Sparse autoencoders (SAEs) have become a central tool for interpreting language models. However, two key SAE analyses that remain difficult to scale are (1) matching semantically similar features across multi-layers and (2) compressing…

Machine Learning · Computer Science 2026-05-28 Tue M. Cao , Nguyen Do , My T. Thai

Sparse autoencoders (SAEs) have recently emerged as pivotal tools for introspection into large language models. SAEs can uncover high-quality, interpretable features at different levels of granularity and enable targeted steering of the…

Information Retrieval · Computer Science 2026-01-19 Martin Spišák , Ladislav Peška , Petr Škoda , Vojtěch Vančura , Rodrigo Alves

Artistic style transfer in generative models remains a significant challenge, as existing methods often introduce style only via model fine-tuning, additional adapters, or prompt engineering, all of which can be computationally expensive…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Raina Panda , Daniel Fein , Arpita Singhal , Mark Fiore , Maneesh Agrawala , Matyas Bohacek

Transformer models have become state-of-the-art in decoding stimuli and behavior from neural activity, significantly advancing neuroscience research. Yet greater transparency in their decision-making processes would substantially enhance…

Quantitative Methods · Quantitative Biology 2025-06-18 Laurence Freeman , Philip Shamash , Vinam Arora , Caswell Barry , Tiago Branco , Eva Dyer