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Heterogeneity in the cell population of cancer tissues poses many challenges in cancer diagnosis and treatment. Studying the heterogeneity in cell populations from gene expression measurement data in the context of cancer research is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-31 Anik Chaudhuri , Anwoy Mohanty , Manoranjan Satpathy

SAGECal has been designed to find the most accurate calibration solutions for low radio frequency imaging observations, with minimum artefacts due to incomplete sky models. SAGECAL is developed to handle extremely large datasets, e.g., when…

Instrumentation and Methods for Astrophysics · Physics 2019-10-31 Hanno Spreeuw , Ben van Werkhoven , Sarod Yatawatta , Faruk Diblen

GPU architectural simulation is orders of magnitude slower than native execution, necessitating workload sampling for practical speedups. Existing methods rely on hand-crafted features with limited expressiveness, yielding either aggressive…

Performance · Computer Science 2026-03-03 Jiaqi Wang , Jingwei Sun , Jiyu Luo , Han Li , Guangzhong Sun

Advancements in AI have greatly enhanced the medical imaging process, making it quicker to diagnose patients. However, very few have investigated the optimization of a multi-model system with hardware acceleration. As specialized edge…

Hardware Architecture · Computer Science 2025-10-03 Ashiyana Abdul Majeed , Mahmoud Meribout , Safa Mohammed Sali

Recent years have witnessed a rapid advancement in GPU technology, establishing it as a formidable high-performance parallel computing technology with superior floating-point computational capabilities compared to traditional CPUs. This…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-18 Xinyao Yi , Yuxin Qiao

Bayesian spectral deconvolution provides a data-driven framework for mathematical model selection and parameter estimation from spectral data. Although highly versatile, it becomes computationally expensive as the number of model…

Computation · Statistics 2026-04-07 Tomohiro Nabika , Yui Hayashi , Masato Okada

Large Language Models (LLMs) face significant deployment challenges due to their substantial resource requirements. While low-bit quantized weights can reduce memory usage and improve inference efficiency, current hardware lacks native…

Machine Learning · Computer Science 2025-06-10 Pengxiang Zhao , Xiaoming Yuan

Large-language models (LLMs) are rapidly being applied to radiology, enabling automated image interpretation and report generation tasks. Their deployment in clinical practice requires both high diagnostic accuracy and low inference…

Tissues and Organs · Quantitative Biology 2025-11-11 Jyun-Ping Kao

Significance: Monte Carlo (MC) methods are the gold-standard for modeling light-tissue interactions due to their accuracy. Mesh-based MC (MMC) offers enhanced precision for complex tissue structures using tetrahedral mesh models. Despite…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-01 Shijie Yan , Douglas Dwyer , David R. Kaeli , Qianqian Fang

Integration of quantum computing in generative machine learning models has the potential to offer benefits such as training speed-up and superior feature extraction. However, the existing quantum generative adversarial networks (QGANs) fail…

Quantum Physics · Physics 2025-05-15 Amena Khatun , Kübra Yeter Aydeniz , Yaakov S. Weinstein , Muhammad Usman

Graph Neural Networks (GNNs) have shown great superiority on non-Euclidean graph data, achieving ground-breaking performance on various graph-related tasks. As a practical solution to train GNN on large graphs with billions of nodes and…

Machine Learning · Computer Science 2024-09-24 Zeyu Zhu , Peisong Wang , Qinghao Hu , Gang Li , Xiaoyao Liang , Jian Cheng

Graph Convolutional Networks (GCNs) are pivotal in extracting latent information from graph data across various domains, yet their acceleration on mainstream GPUs is challenged by workload imbalance and memory access irregularity. To…

Hardware Architecture · Computer Science 2023-08-24 Xi Xie , Hongwu Peng , Amit Hasan , Shaoyi Huang , Jiahui Zhao , Haowen Fang , Wei Zhang , Tong Geng , Omer Khan , Caiwen Ding

We investigate the problem of certifying optimality for sparse generalized linear models (GLMs), where sparsity is enforced through a cardinality constraint. While Branch-and-Bound (BnB) frameworks can certify optimality using perspective…

Optimization and Control · Mathematics 2026-03-03 Jiachang Liu , Andrea Lodi , Soroosh Shafiee

Single-cell sequencing technologies reveal cellular heterogeneity at high resolution, advancing our understanding of biological complexity. As datasets start to scale to tens of millions of cells, computational workflows face substantial…

Beagle is a new software framework that enables execution of Genetic Programming tasks on the GPU. Currently available for symbolic regression, it processes individuals of the population and fitness cases for training in a way that…

Neural and Evolutionary Computing · Computer Science 2026-03-16 Nathan Haut , Ilya Basin , Marzieh Kianinejad , Ruchika Gupta , Elijah Smith , Zachary Perrico , Wolfgang Banzhaf

In recent years, the Hamiltonian Monte Carlo (HMC) algorithm has been found to work more efficiently compared to other popular Markov Chain Monte Carlo (MCMC) methods (such as random walk Metropolis-Hastings) in generating samples from a…

Computation · Statistics 2014-02-18 Andrew L. Beam , Sujit K. Ghosh , Jon Doyle

We demonstrate a GPU-accelerated nested sampling framework for efficient high-dimensional Bayesian inference in cosmology. Using JAX-based neural emulators and likelihoods for cosmic microwave background and cosmic shear analyses, our…

Cosmology and Nongalactic Astrophysics · Physics 2025-10-08 Toby Lovick , David Yallup , Davide Piras , Alessio Spurio Mancini , Will Handley

B-spline modeling is fundamental to CAD systems, and its evaluation and manipulation algorithms currently in use were developed decades ago, specifically for CPU architectures. While remaining effective for many applications, these…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-17 Jiayu Wu , Qiang Zou

Quantification of tissue parameters using MRI is emerging as a powerful tool in clinical diagnosis and research studies. The need for multiple long scans with different acquisition parameters prohibits quantitative MRI from reaching…

Quantitative Methods · Quantitative Biology 2024-08-07 Amir Heydari , Abbas Ahmadi , Tae Hyung Kim , Berkin Bilgic

While Model Predictive Control (MPC) delivers strong performance across robotics applications, solving the underlying (batches of) nonlinear trajectory optimization (TO) problems online remains computationally demanding. Existing…

Robotics · Computer Science 2026-05-11 Alexander Du , Emre Adabag , Gabriel Bravo-Palacios , Brian Plancher
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