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Designing molecules with optimized properties remains a fundamental challenge due to the intricate relationship between molecular structure and properties. Traditional computational approaches that address the combinatorial number of…

Quantum Physics · Physics 2025-08-25 Francesco Calcagno , Delmar G. A. Cabral , Ivan Rivalta , Victor S. Batista

Critical decision-making issues in science, engineering, and industry are based on combinatorial optimization; however, its application is inherently limited by the NP-hard nature of the problem. A specialized paradigm of analogue quantum…

Quantum Physics · Physics 2026-02-04 Rudraksh Sharma , Ravi Katukam , Arjun Nagulapally

Black-box optimization minimizes an objective function without derivatives or explicit forms. Such an optimization method with continuous variables has been successful in the fields of machine learning and material science. For discrete…

Quadratic unconstrained binary optimization (QUBO) is a field of operations research that is attracting growing interest due to the recent availability of quantum hardware targeted at solving QUBO problems. However, practical adoption is…

Software Engineering · Computer Science 2026-01-22 Lodovica Marchesi , Amal Nasharti , Michele Marchesi

Recent experimental breakthroughs have signalled the imminent arrival of the early fault-tolerant era. However, for a considerable period in the foreseeable future, relying solely on quantum error correction for full error suppression will…

Quantum Physics · Physics 2025-02-18 Kecheng Liu , Zhenyu Cai

The presence of a bias field, encoding some information about the target state, can enhance the performance of quantum optimization methods. Here we investigate the effect of such a bias field on the outcome of quantum annealing sampling,…

Quantum Physics · Physics 2022-10-19 Tobias Graß

Bayesian optimisation (BO) has been a successful approach to optimise functions which are expensive to evaluate and whose observations are noisy. Classical BO algorithms, however, do not account for errors about the location where…

Machine Learning · Computer Science 2019-02-22 Rafael Oliveira , Lionel Ott , Fabio Ramos

The adoption of high-fidelity models for many-query optimization problems is majorly limited by the significant computational cost required for their evaluation at every query. Multifidelity Bayesian methods (MFBO) allow to include costly…

Machine Learning · Computer Science 2024-07-08 Francesco Di Fiore , Laura Mainini

We consider the problem of estimating the expected outcomes of Monte Carlo processes whose outputs are described by multidimensional random variables. We tightly characterize the quantum query complexity of this problem for various choices…

Quantum Physics · Physics 2021-07-09 Arjan Cornelissen , Sofiene Jerbi

We leverage the idea of a statistical ensemble to improve the quality of quantum annealing based binary compressive sensing. Since executing quantum machine instructions on a quantum annealer can result in an excited state, rather than the…

Quantum Physics · Physics 2020-06-09 Ramin Ayanzadeh , Milton Halem , Tim Finin

A new methodology is proposed to solve classical Boolean problems as Hamiltonians, using the quantum approximate optimization algorithm (QAOA). Our methodology successfully finds all optimized approximated solutions for Boolean problems,…

Quantum Physics · Physics 2024-07-11 Ali Al-Bayaty , Marek Perkowski

In this paper we present a novel strategy to solve optimization problems within a hybrid quantum-classical scheme based on quantum annealing, with a particular focus on QUBO problems. The proposed algorithm is based on an iterative…

Quantum Physics · Physics 2020-04-07 Enrico Blanzieri , Davide Pastorello

Estimation of physical observables for unknown quantum states is an important problem that underlies a wide range of fields, including quantum information processing, quantum physics, and quantum chemistry. In the context of quantum…

Quantum Physics · Physics 2024-05-21 Yuma Nakamura , Yoshichika Yano , Nobuyuki Yoshioka

In applications such as molecule design or drug discovery, it is desirable to have an algorithm which recommends new candidate molecules based on the results of past tests. These molecules first need to be synthesized and then tested for…

Quantum approximate optimization algorithm (QAOA) is one of the popular quantum algorithms that are used to solve combinatorial optimization problems via approximations. QAOA is able to be evaluated on both physical and virtual quantum…

Quantum Physics · Physics 2023-12-07 Yu-Cheng Lin , Chuan-Chi Wang , Chia-Heng Tu , Shih-Hao Hung

Quantum phase estimation (QPE) is the key subroutine of several quantum computing algorithms as well as a central ingredient in quantum computational chemistry and quantum simulation. While QPE strategies have focused on the estimation of a…

Quantum Physics · Physics 2021-07-26 Valentin Gebhart , Augusto Smerzi , Luca Pezzè

In Phys. Rev. A 108, L060402 (2023), we introduced a Bayesian measurement error mitigation algorithm, which leveraged complete information from the readout signal, and validated the protocol on a quantum device with five superconducting…

Quantum Physics · Physics 2025-11-18 F. Cosco , F. Plastina , N. Lo Gullo

The feedback-based algorithm for quantum optimization (FALQON) has recently been proposed to solve quadratic unconstrained binary optimization problems. This paper efficiently generalizes FALQON to tackle quadratic constrained binary…

Quantum Physics · Physics 2025-04-15 Salahuddin Abdul Rahman , Özkan Karabacak , Rafal Wisniewski

Satellite mission planning for Earth observation satellites is a combinatorial optimization problem that consists of selecting the optimal subset of imaging requests, subject to constraints, to be fulfilled during an orbit pass of a…

Data flow scheduling for high-throughput multibeam satellites is a challenging NP-hard combinatorial optimization problem. As the problem scales, traditional methods, such as Mixed-Integer Linear Programming and heuristic schedulers, often…

Quantum Physics · Physics 2026-03-03 Qiben Yan , John P. T. Stenger , Daniel Gunlycke
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