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Diabetic retinopathy (DR) is one of the major blindness-causing diseases currently known. Automatic grading of DR using deep learning methods not only speeds up the diagnosis of the disease but also reduces the rate of misdiagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-25 Lei Shi , Bin Wang , Junxing Zhang

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Understanding the interactions between biomarkers among brain regions during neurodegenerative disease is essential for unravelling the mechanisms underlying disease progression. For example, pathophysiological models of Alzheimer's Disease…

Artificial Intelligence · Computer Science 2025-11-17 Tiantian He , An Zhao , Elinor Thompson , Anna Schroder , Ahmed Abdulaal , Frederik Barkhof , Daniel C. Alexander

In recent years, artificial intelligence (AI) systems have come to the forefront. These systems, mostly based on Deep learning (DL), achieve excellent results in areas such as image processing, natural language processing, or speech…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Frantisek Sefcik , Wanda Benesova

Recent studies have made remarkable progress in histopathology classification. Based on current successes, contemporary works proposed to further upgrade the model towards a more generalizable and robust direction through incrementally…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Yu Zhu , Kang Li , Lequan Yu , Pheng-Ann Heng

The integration of Artificial Intelligence (AI) into pathology faces a fundamental challenge: black-box predictive models lack transparency, while generative approaches risk clinical hallucination. A case-based retrieval paradigm offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Qifeng Zhou , Wenliang Zhong , Thao M. Dang , Hehuan Ma , Saiyang Na , Yuzhi Guo , Junzhou Huang

Diabetic retinopathy (DR) is a leading cause of vision loss worldwide, and early diagnosis through automated retinal image analysis can significantly reduce the risk of blindness. This paper presents a robust deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Faisal Ahmed

This paper presents a multitask deep learning model to detect all the five stages of diabetic retinopathy (DR) consisting of no DR, mild DR, moderate DR, severe DR, and proliferate DR. This multitask model consists of one classification…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Sharmin Majumder , Nasser Kehtarnavaz

Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of preventable blindness among working-age adults. Traditional approaches in the literature focus on standard color fundus photography (CFP) for the detection of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Pablo Jimenez-Lizcano , Sergio Romero-Tapiador , Ruben Tolosana , Aythami Morales , Guillermo González de Rivera , Ruben Vera-Rodriguez , Julian Fierrez

In this paper, we propose two distinct solutions to the problem of Diabetic Retinopathy (DR) classification. In the first approach, we introduce a shallow neural network architecture. This model performs well on classification of the most…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Hangwei Zhuang , Nabil Ettehadi

Domain generalization is critical in computational pathology (CPath) due to inherent domain shifts caused by variations in staining protocols, scanner devices, and imaging settings across clinical centers. Vision-language models (VLMs),…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Amir Mohammad Ezzati , Alireza Malekhosseini , Armin Khosravi , Mohammad Hossein Rohban

Advancements in artificial intelligence (AI) are transforming pathology by integrat-ing large language models (LLMs) with retrieval-augmented generation (RAG) and domain-specific foundation models. This study explores the application of…

Computation and Language · Computer Science 2025-05-14 Hussien Al-Asi , Jordan P Reynolds , Shweta Agarwal , Bryan J Dangott , Aziza Nassar , Zeynettin Akkus

Large Language Models (LLMs) are prone to hallucination, especially during multi-hop and reasoning-intensive tasks such as mathematical problem solving. While Outcome Reward Models verify only final answers, Process Reward Models (PRMs)…

Computation and Language · Computer Science 2025-05-27 Tej Deep Pala , Panshul Sharma , Amir Zadeh , Chuan Li , Soujanya Poria

Diabetic retinopathy (DR) is a complication of diabetes that severely affects eyes. It can be graded into five levels of severity according to international protocol. However, optimizing a grading model to have strong generalizability…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Yi Zhou , Boyang Wang , Xiaodong He , Shanshan Cui , Ling Shao

In pathology, the rarity of certain diseases and the complexity in annotating pathological images significantly hinder the creation of extensive, high-quality datasets. This limitation impedes the progress of deep learning-assisted…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Hao Quan , Xinjia Li , Dayu Hu , Tianhang Nan , Xiaoyu Cui

This article aims to classify diabetic retinopathy (DR) disease into five different classes using an ensemble approach based on two popular pre-trained convolutional neural networks: VGG16 and Inception V3. The proposed model aims to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Susmita Ghosh , Abhiroop Chatterjee

Diabetic retinopathy is a common complication of diabetes, and monitoring the progression of retinal abnormalities using fundus imaging is crucial. Because the images must be interpreted by a medical expert, it is infeasible to screen all…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Andrea M. Storås , Josefine V. Sundgaard

Accurate prediction of molecular properties is crucial in drug discovery. Traditional methods often overlook that real-world molecules typically exhibit multiple property labels with complex correlations. To this end, we propose a novel…

Quantitative Methods · Quantitative Biology 2024-08-13 Linjia Kang , Songhua Zhou , Shuyan Fang , Shichao Liu

Deep learning methods for ophthalmic diagnosis have shown considerable success in tasks like segmentation and classification. However, their widespread application is limited due to the models being opaque and vulnerable to making a wrong…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Amitojdeep Singh , Sourya Sengupta , Mohammed Abdul Rasheed , Varadharajan Jayakumar , Vasudevan Lakshminarayanan

Diabetic Retinopathy (DR) progresses as a continuous and irreversible deterioration of the retina, following a well-defined clinical trajectory from mild to severe stages. However, most existing ordinal regression approaches model DR…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Huangwei Chen , Junhao Jia , Ruocheng Li , Cunyuan Yang , Wu Li , Xiaotao Pang , Yifei Chen , Haishuai Wang , Jiajun Bu , Lei Wu
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