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Medical foundation models, pre-trained with large-scale clinical data, demonstrate strong performance in diverse clinically relevant applications. RETFound, trained on nearly one million retinal images, exemplifies this approach in…

The advent of foundation models (FMs) is transforming medical domain. In ophthalmology, RETFound, a retina-specific FM pre-trained sequentially on 1.4 million natural images and 1.6 million retinal images, has demonstrated high adaptability…

Background: RETFound, a self-supervised, retina-specific foundation model (FM), showed potential in downstream applications. However, its comparative performance with traditional deep learning (DL) models remains incompletely understood.…

Foundation models have advanced machine learning across various modalities, including images. Recently multiple teams trained foundation models specialized for remote sensing applications. This line of research is motivated by the distinct…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Ani Vanyan , Alvard Barseghyan , Hakob Tamazyan , Tigran Galstyan , Vahan Huroyan , Naira Hovakimyan , Hrant Khachatrian

There is an increasing number of medical use-cases where classification algorithms based on deep neural networks reach performance levels that are competitive with human medical experts. To alleviate the challenges of small dataset sizes,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-28 Vignesh Srinivasan , Nils Strodthoff , Jackie Ma , Alexander Binder , Klaus-Robert Müller , Wojciech Samek

Background and objective: Cell-level pathological image analysis requires working with extremely small image patches (40x40 pixels), far below standard ImageNet resolutions. It remains unclear whether modern deep learning architectures and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Hiroki Kagiyama , Toru Nagasaka , Yukari Adachi , Takaaki Tachibana , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

Foundation models, i.e., very large deep learning models, have demonstrated impressive performances in various language and vision tasks that are otherwise difficult to reach using smaller-size models. The major success of GPT-type of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Yiqun Xie , Zhihao Wang , Weiye Chen , Zhili Li , Xiaowei Jia , Yanhua Li , Ruichen Wang , Kangyang Chai , Ruohan Li , Sergii Skakun

Deep learning is currently the state-of-the-art for automated detection of referable diabetic retinopathy (DR) from color fundus photographs (CFP). While the general interest is put on improving results through methodological innovations,…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Tomás Castilla , Marcela S. Martínez , Mercedes Leguía , Ignacio Larrabide , José Ignacio Orlando

With access to large-scale, unlabeled medical datasets, researchers are confronted with two questions: Should they attempt to pretrain a custom foundation model on this medical data, or use transfer-learning from an existing generalist…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Jakob Ambsdorf , Asbjørn Munk , Sebastian Llambias , Anders Nymark Christensen , Kamil Mikolaj , Randall Balestriero , Martin Tolsgaard , Aasa Feragen , Mads Nielsen

Foundation models are predominantly trained in an unsupervised or self-supervised manner on highly diverse and large-scale datasets, making them broadly applicable to various downstream tasks. In this work, we investigate for the first time…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Tahar Chettaoui , Naser Damer , Fadi Boutros

The Vision-Language Foundation model is increasingly investigated in the fields of computer vision and natural language processing, yet its exploration in ophthalmology and broader medical applications remains limited. The challenge is the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jiawei Du , Jia Guo , Weihang Zhang , Shengzhu Yang , Hanruo Liu , Huiqi Li , Ningli Wang

The adoption of neural network models in medical imaging has been constrained by strict privacy regulations, limited data availability, high acquisition costs, and demographic biases. Deep generative models offer a promising solution by…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 Zuzanna Skorniewska , Bartlomiej W. Papiez

Foundation models, large-scale, pre-trained deep-learning models adapted to a wide range of downstream tasks have gained significant interest lately in various deep-learning problems undergoing a paradigm shift with the rise of these…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Bobby Azad , Reza Azad , Sania Eskandari , Afshin Bozorgpour , Amirhossein Kazerouni , Islem Rekik , Dorit Merhof

Retinopathy represents a group of retinal diseases that, if not treated timely, can cause severe visual impairments or even blindness. Many researchers have developed autonomous systems to recognize retinopathy via fundus and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Taimur Hassan , Bilal Hassan , Muhammad Usman Akram , Shahrukh Hashmi , Abdel Hakim Taguri , Naoufel Werghi

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, necessitating early detection to prevent vision loss. Current automated DR detection systems often struggle with poor-quality images, lack interpretability, and…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Idowu Paul Okuwobi , Jingyuan Liu , Jifeng Wan , Jiaojiao Jiang

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu

The deep learning field is converging towards the use of general foundation models that can be easily adapted for diverse tasks. While this paradigm shift has become common practice within the field of natural language processing, progress…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Joana Palés Huix , Adithya Raju Ganeshan , Johan Fredin Haslum , Magnus Söderberg , Christos Matsoukas , Kevin Smith

Foundation models are widely employed in medical image analysis, due to their high adaptability and generalizability for downstream tasks. With the increasing number of foundation models being released, model selection has become an…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Fuping Wu , Bartlomiej W. Papiez

Retinal blood vessel segmentation can extract clinically relevant information from fundus images. As manual tracing is cumbersome, algorithms based on Convolution Neural Networks have been developed. Such studies have used small publicly…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Jeremiah Fadugba , Patrick Köhler , Lisa Koch , Petru Manescu , Philipp Berens

Foundation models (FMs) promise to generalize medical imaging, but their effectiveness varies. It remains unclear how pre-training domain (medical vs. general), paradigm (e.g., text-guided), and architecture influence embedding quality,…

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