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Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

Machine Learning · Statistics 2023-04-11 Alan Nawzad Amin , Eli Nathan Weinstein , Debora Susan Marks

The rapid expansion of scholarly publications across diverse disciplines has made it increasingly difficult to systematically evaluate how research contributes to the United Nations Sustainable Development Goals (SDGs). Domain…

Digital Libraries · Computer Science 2026-01-27 Sahil Dewani , Kiran Sharma

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

Data-driven scientific discovery requires the iterative integration of scientific domain knowledge, statistical expertise, and an understanding of data semantics to make nuanced analytical decisions, e.g., about which variables,…

Intrusion detection has been a key topic in the field of cyber security, and the common network threats nowadays have the characteristics of varieties and variation. Considering the serious imbalance of intrusion detection datasets will…

Cryptography and Security · Computer Science 2022-04-15 Zhewei Chen , Wenwen Yu , Linyue Zhou

In Big Data environment, one pressing challenge facing engineers is to perform reliability analysis for a large fleet of heterogeneous repairable systems with covariates. In addition to static covariates, which include time-invariant system…

Applications · Statistics 2019-04-03 Xiao Liu , Rong Pan

Hyperbolic space is becoming a popular choice for representing data due to the hierarchical structure - whether implicit or explicit - of many real-world datasets. Along with it comes a need for algorithms capable of solving fundamental…

Machine Learning · Computer Science 2024-06-25 Lars Doorenbos , Pablo Márquez-Neila , Raphael Sznitman , Pascal Mettes

Nowadays new technologies, and especially artificial intelligence, are more and more established in our society. Big data analysis and machine learning, two sub-fields of artificial intelligence, are at the core of many recent breakthroughs…

Machine Learning · Statistics 2021-06-22 Antonio Sutera

Comparative transcriptomics has gained increasing popularity in genomic research thanks to the development of high-throughput technologies including microarray and next-generation RNA sequencing that have generated numerous transcriptomic…

Quantitative Methods · Quantitative Biology 2021-12-01 Wei Vivian Li , Yiling Chen , Jingyi Jessica Li

The connect-fill-run workflow paradigm, widely adopted in mature software engineering, accelerates collaborative development. However, computational chemistry, computational materials science, and computational biology face persistent…

Chemical Physics · Physics 2025-08-12 Jianan Wang , Wenbo Guo , Xin Yue , Minjie Xu , Yueqiang Zheng , Jingxiang Dong , Jiarui Hu , Jian Xia , Chuixiong Wu

Model parameter inference is a universal problem across science. This challenge is particularly pronounced in developmental biology, where faithful mechanistic descriptions require spatial-stochastic models with numerous parameters, yet…

Biological Physics · Physics 2024-07-16 Michael A. Ramirez-Sierra , Thomas R. Sokolowski

Atomic-level simulations are widely used to study biomolecules and their dynamics. A common goal in such studies is to compare simulations of a molecular system under several conditions -- for example, with various mutations or bound…

Biomolecules · Quantitative Biology 2025-01-07 Martin Vögele , Neil J. Thomson , Sang T. Truong , Jasper McAvity , Ulrich Zachariae , Ron O. Dror

The ability to compare between individuals or organisations fairly is important for the development of robust and meaningful quantitative benchmarks. To make fair comparisons, contextual factors must be taken into account, and comparisons…

Applications · Statistics 2020-11-18 Daniel W. Kennedy , Jessica Cameron , Paul P. -Y. Wu , Kerrie Mengersen

Merging the two cultures of deep and statistical learning provides insights into structured high-dimensional data. Traditional statistical modeling is still a dominant strategy for structured tabular data. Deep learning can be viewed…

Methodology · Statistics 2021-10-25 Anindya Bhadra , Jyotishka Datta , Nick Polson , Vadim Sokolov , Jianeng Xu

The usage of machine learning methods in traditional surveys including official statistics, is still very limited. Therefore, we propose a predictor supported by these algorithms, which can be used to predict any population or subpopulation…

Methodology · Statistics 2025-07-14 Tomasz Żądło , Adam Chwila

In medical domain, data features often contain missing values. This can create serious bias in the predictive modeling. Typical standard data mining methods often produce poor performance measures. In this paper, we propose a new method to…

Machine Learning · Statistics 2015-03-24 Talayeh Razzaghi , Oleg Roderick , Ilya Safro , Nick Marko

Farmers in developing regions like Karnataka, India, face a dual challenge: navigating extreme market and climate volatility while being excluded from the digital revolution due to literacy barriers. This paper presents a novel decision…

Machine Learning · Computer Science 2025-07-15 Niranjan Mallikarjun Sindhur , Pavithra C , Nivya Muchikel

Supervised operator learning centers on the use of training data, in the form of input-output pairs, to estimate maps between infinite-dimensional spaces. It is emerging as a powerful tool to complement traditional scientific computing,…

Machine Learning · Computer Science 2024-08-14 Nicholas H. Nelsen , Andrew M. Stuart

Current research in biology heavily depends on the availability and efficient use of information. In order to build new knowledge, various sources of biological data must often be combined. Semantic Web technologies, which provide a common…

Quantitative Methods · Quantitative Biology 2009-02-19 Claude Pasquier
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