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Instruction tuning is a pivotal technique for aligning large language models (LLMs) with human intentions, safety constraints, and domain-specific requirements. This survey provides a comprehensive overview of the full pipeline,…

Computation and Language · Computer Science 2025-11-20 Xudong Han , Junjie Yang , Tianyang Wang , Ziqian Bi , Xinyuan Song , Junfeng Hao , Junhao Song

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Pre-trained language models (LMs) are shown to easily generate toxic language. In this work, we systematically explore domain-adaptive training to reduce the toxicity of language models. We conduct this study on three dimensions: training…

Computation and Language · Computer Science 2022-10-25 Boxin Wang , Wei Ping , Chaowei Xiao , Peng Xu , Mostofa Patwary , Mohammad Shoeybi , Bo Li , Anima Anandkumar , Bryan Catanzaro

Large Language Model (LLM) pre-training exhausts an ever growing compute budget, yet recent research has demonstrated that careful document selection enables comparable model quality with only a fraction of the FLOPs. Inspired by efforts…

Computation and Language · Computer Science 2024-06-10 Xiang Kong , Tom Gunter , Ruoming Pang

We propose a novel task-agnostic in-domain pre-training method that sits between generic pre-training and fine-tuning. Our approach selectively masks in-domain keywords, i.e., words that provide a compact representation of the target…

Computation and Language · Computer Science 2023-07-17 Shahriar Golchin , Mihai Surdeanu , Nazgol Tavabi , Ata Kiapour

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

In 2012, the United Nations introduced 17 Sustainable Development Goals (SDGs) aimed at creating a more sustainable and improved future by 2030. However, tracking progress toward these goals is difficult because of the extensive scale and…

Large Language Models (LLMs) hold promise in automating data analysis tasks, yet open-source models face significant limitations in these kinds of reasoning-intensive scenarios. In this work, we investigate strategies to enhance the data…

Computation and Language · Computer Science 2025-11-14 Yuqi Zhu , Yi Zhong , Jintian Zhang , Ziheng Zhang , Shuofei Qiao , Yujie Luo , Lun Du , Da Zheng , Ningyu Zhang , Huajun Chen

Small Language Models (SLMs) are becoming increasingly popular in specialized fields, such as industrial applications, due to their efficiency, lower computational requirements, and ability to be fine-tuned for domain-specific tasks,…

Computation and Language · Computer Science 2025-10-22 Shuxin Lin , Dhaval Patel , Christodoulos Constantinides

Programmatic weak supervision methodologies facilitate the expedited labeling of extensive datasets through the use of label functions (LFs) that encapsulate heuristic data sources. Nonetheless, the creation of precise LFs necessitates…

Computation and Language · Computer Science 2023-11-03 Naiqing Guan , Kaiwen Chen , Nick Koudas

Software vulnerability detection is generally supported by automated static analysis tools, which have recently been reinforced by deep learning (DL) models. However, despite the superior performance of DL-based approaches over rule-based…

Software Engineering · Computer Science 2024-05-03 Yanjing Yang , Xin Zhou , Runfeng Mao , Jinwei Xu , Lanxin Yang , Yu Zhangm , Haifeng Shen , He Zhang

Large language models (LLMs), such as ChatGPT, have demonstrated impressive performance in the text generation task, showing the ability to understand and respond to complex instructions. However, the performance of naive LLMs in speciffc…

Computation and Language · Computer Science 2025-12-12 HuangChao Xu , Baohua Zhang , Zhong Jin , Tiannian Zhu , Quansheng Wu , Hongming Weng

Pre-trained large language models (PLMs) underlie most new developments in natural language processing. They have shifted the field from application-specific model pipelines to a single model that is adapted to a wide range of tasks.…

Computation and Language · Computer Science 2023-06-30 Joshua Maynez , Priyanka Agrawal , Sebastian Gehrmann

Large Language Models (LLMs) such as GPT-4 and Llama3 have significantly impacted various fields by enabling high-quality synthetic data generation and reducing dependence on expensive human-generated datasets. Despite this, challenges…

Computation and Language · Computer Science 2025-11-18 Yue Huang , Siyuan Wu , Chujie Gao , Dongping Chen , Qihui Zhang , Yao Wan , Tianyi Zhou , Jianfeng Gao , Chaowei Xiao , Lichao Sun , Xiangliang Zhang

The in-context learning ability of large language models (LLMs) enables them to generalize to novel downstream tasks with relatively few labeled examples. However, they require enormous computational resources to be deployed. Alternatively,…

Computation and Language · Computer Science 2024-01-09 Jean Kaddour , Qi Liu

The emergence of large language models (LLMs) has significantly impacted various fields, from natural language processing to sectors like medicine and finance. However, despite their rapid proliferation, the applications of LLMs in…

Information Theory · Computer Science 2025-05-06 Ali Maatouk , Kenny Chirino Ampudia , Rex Ying , Leandros Tassiulas

Recently, large language models (LLMs) have outperformed human experts in predicting the results of neuroscience experiments (Luo et al., 2024). What is the basis for this performance? One possibility is that statistical patterns in that…

Neurons and Cognition · Quantitative Biology 2024-07-03 Xiaoliang Luo , Guangzhi Sun , Bradley C. Love

Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang

Recent advancements in Large Language Models (LLMs) have demonstrated exceptional capabilities in natural language understanding and generation. While these models excel in general complex reasoning tasks, they still face challenges in…

Artificial Intelligence · Computer Science 2024-10-25 Graziano A. Manduzio , Federico A. Galatolo , Mario G. C. A. Cimino , Enzo Pasquale Scilingo , Lorenzo Cominelli

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

Computation and Language · Computer Science 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov