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The rapid advancement of Large Language Models (LLMs), reasoning models, and agentic AI approaches coincides with a growing global mental health crisis, where increasing demand has not translated into adequate access to professional…

Human-Computer Interaction · Computer Science 2025-04-03 Kellie Yu Hui Sim , Kenny Tsu Wei Choo

Large Language Models (LLMs) are transforming mental health care by enhancing accessibility, personalization, and efficiency in therapeutic interventions. These AI-driven tools empower mental health professionals with real-time support,…

Computers and Society · Computer Science 2025-01-22 Hari Mohan Pandey

We investigate the role of large language models (LLMs) in supporting mental health by analyzing Reddit posts and comments about mental health conversations with ChatGPT. Our findings reveal that users value ChatGPT as a safe,…

Human-Computer Interaction · Computer Science 2025-10-28 Kyuha Jung , Gyuho Lee , Yuanhui Huang , Yunan Chen

Conversational Agents (CAs) acting as peer supporters have been widely studied and demonstrated beneficial for people's mental health. However, previous peer support CAs either are user-initiated or follow predefined rules to initiate the…

Human-Computer Interaction · Computer Science 2024-08-07 Tianjian Liu , Hongzheng Zhao , Yuheng Liu , Xingbo Wang , Zhenhui Peng

The 2022 World Mental Health Report calls for global mental health care reform, amid rising prevalence of issues like anxiety and depression that affect nearly one billion people worldwide. Traditional in-person therapy fails to meet this…

Computers and Society · Computer Science 2025-10-21 Xun Wei , Pukai Zhou , Zeyu Wang

The global mental health crisis is looming with a rapid increase in mental disorders, limited resources, and the social stigma of seeking treatment. As the field of artificial intelligence (AI) has witnessed significant advancements in…

Computation and Language · Computer Science 2023-11-27 Neo Christopher Chung , George Dyer , Lennart Brocki

Large language models (LLMs) and LLM-based agents are increasingly deployed as assistants in planning and decision making, yet most existing systems are implicitly optimized for a single-principal interaction paradigm, in which the model is…

Computation and Language · Computer Science 2026-04-29 Shu Yang , Shenzhe Zhu , Hao Zhu , José Ramón Enríquez , Di Wang , Alex Pentland , Michiel A. Bakker , Jiaxin Pei

Client-Service Representatives (CSRs) are vital to organizations. Frequent interactions with disgruntled clients, however, disrupt their mental well-being. To help CSRs regulate their emotions while interacting with uncivil clients, we…

Large Multimodal Models (LMMs) have shown strong potential for assisting users in tasks, such as programming, content creation, and information access, yet their interaction remains largely limited to traditional interfaces such as desktops…

Human-Computer Interaction · Computer Science 2026-02-12 Liuchuan Yu , Yongqi Zhang , Lap-Fai Yu

Large Language Models (LLMs) are increasingly used in healthcare, yet ensuring their safety and trustworthiness remains a barrier to deployment. Conversational medical assistants must avoid unsafe compliance without over-refusing benign…

Artificial Intelligence · Computer Science 2025-12-05 Huy Nghiem , Swetasudha Panda , Devashish Khatwani , Huy V. Nguyen , Krishnaram Kenthapadi , Hal Daumé

People experiencing severe distress increasingly use Large Language Model (LLM) chatbots as mental health support tools. Discussions on social media have described how engagements were lifesaving for some, but evidence suggests that…

Human-Computer Interaction · Computer Science 2025-05-12 Inhwa Song , Sachin R. Pendse , Neha Kumar , Munmun De Choudhury

Applying large language models (LLMs) to assist in psycho-counseling is an emerging and meaningful approach, driven by the significant gap between patient needs and the availability of mental health support. However, current LLMs struggle…

Computation and Language · Computer Science 2026-04-14 Mian Zhang , Shaun M. Eack , Zhiyu Zoey Chen

Large language models (LLMs) are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned, particularly in sensitive or high-risk contexts. Existing…

Human-Computer Interaction · Computer Science 2026-01-21 Jiwon Kim , Violeta J. Rodriguez , Dong Whi Yoo , Eshwar Chandrasekharan , Koustuv Saha

Large Language Models (LLMs) are increasingly utilized for mental health support; however, current safety benchmarks often fail to detect the complex, longitudinal risks inherent in therapeutic dialogue. We introduce an evaluation framework…

Computation and Language · Computer Science 2026-03-06 Ian Steenstra , Paola Pedrelli , Weiyan Shi , Stacy Marsella , Timothy W. Bickmore

Despite the plethora of telehealth applications to assist home-based older adults and healthcare providers, basic messaging and phone calls are still the most common communication methods, which suffer from limited availability, information…

Computation and Language · Computer Science 2024-02-06 Ziqi Yang , Xuhai Xu , Bingsheng Yao , Shao Zhang , Ethan Rogers , Stephen Intille , Nawar Shara , Guodong Gordon Gao , Dakuo Wang

Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…

Artificial Intelligence · Computer Science 2026-03-03 Shuheng Chen , Namratha Patil , Haonan Pan , Angel Hsing-Chi Hwang , Yao Du , Ruishan Liu , Jieyu Zhao

As large language models (LLMs) are increasingly applied across various domains, enhancing safety while maintaining the helpfulness of LLMs has become a critical challenge. Recent studies solve this problem through safety-constrained online…

Computation and Language · Computer Science 2025-06-04 Yupeng Qi , Ziyu Lyu , Min Yang , Yanlin Wang , Lu Bai , Lixin Cui

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Computation and Language · Computer Science 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

Large Language Models (LLMs) are increasingly being used as autonomous agents capable of performing complicated tasks. However, they lack the ability to perform reliable long-horizon planning on their own. This paper bridges this gap by…

Artificial Intelligence · Computer Science 2025-09-17 Yarin Benyamin , Argaman Mordoch , Shahaf S. Shperberg , Roni Stern

Simulated Patients (SPs) play a crucial role in clinical medical education by providing realistic scenarios for student practice. However, the high cost of training and hiring qualified SPs, along with the heavy workload and potential risks…

Computation and Language · Computer Science 2024-04-26 Yanzeng Li , Cheng Zeng , Jialun Zhong , Ruoyu Zhang , Minhao Zhang , Lei Zou