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Predicting unknown drug-drug interactions (DDIs) is crucial for improving medication safety. Previous efforts in DDI prediction have typically focused on binary classification or predicting DDI categories, with the absence of explanatory…

Computation and Language · Computer Science 2024-09-10 Zhaoyue Sun , Jiazheng Li , Gabriele Pergola , Yulan He

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

Rare diseases represent the long tail of medical imaging, where AI models often fail due to the scarcity of representative training data. In clinical workflows, radiologists frequently consult case reports and literature when confronted…

Computation and Language · Computer Science 2025-11-10 Ha Young Kim , Jun Li , Ana Beatriz Solana , Carolin M. Pirkl , Benedikt Wiestler , Julia A. Schnabel , Cosmin I. Bercea

There is an increasing interest in developing LLMs for medical diagnosis to improve diagnosis efficiency. Despite their alluring technological potential, there is no unified and comprehensive evaluation criterion, leading to the inability…

Computation and Language · Computer Science 2023-08-16 Xiaoming Shi , Jie Xu , Jinru Ding , Jiali Pang , Sichen Liu , Shuqing Luo , Xingwei Peng , Lu Lu , Haihong Yang , Mingtao Hu , Tong Ruan , Shaoting Zhang

Medical reasoning models remain constrained by parametric knowledge and are thus susceptible to forgetting and hallucinations. DeepResearch (DR) models ground outputs in verifiable evidence from tools and perform strongly in general…

Artificial Intelligence · Computer Science 2026-02-05 Zihan Wang , Hao Wang , Shi Feng , Xiaocui Yang , Daling Wang , Yiqun Zhang , Jinghao Lin , Haihua Yang , Xiaozhong Ji

Pharmaceutical research and development has accumulated vast and heterogeneous archives of data. Much of this knowledge stems from discontinued programs, and reusing these archives is invaluable for reverse translation. However, in…

Computation and Language · Computer Science 2025-12-10 Xiaochen Zheng , Alvaro Serra , Ilya Schneider Chernov , Maddalena Marchesi , Eunice Musvasva , Tatyana Y. Doktorova

Chat dialogues contain considerable useful information about a speaker's interests, preferences, and experiences.Thus, knowledge from open-domain chat dialogue can be used to personalize various systems and offer recommendations for…

Machine Learning · Computer Science 2024-02-08 Ryutaro Asahara , Masaki Takahashi , Chiho Iwahashi , Michimasa Inaba

Automated Drug Combination Extraction (DCE) from large-scale biomedical literature is crucial for advancing precision medicine and pharmacological research. However, existing relation extraction methods primarily focus on binary…

Computation and Language · Computer Science 2026-03-10 Zhijun Wang , Ling Luo , Dinghao Pan , Huan Zhuang , Lejing Yu , Yuanyuan Sun , Hongfei Lin

Creating end-to-end bioinformatics workflows requires diverse domain expertise, which poses challenges for both junior and senior researchers as it demands a deep understanding of both genomics concepts and computational techniques. While…

This paper presents our work for the ninth edition of the Dialogue System Technology Challenge (DSTC9). Our solution addresses the track number four: Simulated Interactive MultiModal Conversations. The task consists in providing an…

Computation and Language · Computer Science 2020-12-16 Matteo A. Senese , Alberto Benincasa , Barbara Caputo , Giuseppe Rizzo

Accessing accurate medication insights is vital for enhancing patient safety, minimizing errors, and supporting clinical decision-making. However, healthcare professionals in Africa often rely on manual and time-consuming processes to…

Information Retrieval · Computer Science 2025-02-26 Axum AI , : , J. Owoyemi , S. Abubakar , A. Owoyemi , T. O. Togunwa , F. C. Madubuko , S. Oyatoye , Z. Oyetolu , K. Akyea , A. O. Mohammed , A. Adebakin

Multidisciplinary team (MDT) consultations are the gold standard for cancer care decision-making, yet current practice lacks structured mechanisms for quantifying consensus and ensuring decision traceability. We introduce a Multi-Agent…

Multiagent Systems · Computer Science 2025-12-17 Xudong Han , Xianglun Gao , Xiaoyi Qu , Zhenyu Yu

There are numerous frameworks capable of creating and orchestrating agents to address complex tasks. However, most of them highly coupled Python programming with agent declaration, making it hard for maintenance and runtime optimization. In…

Multiagent Systems · Computer Science 2025-07-29 Sirui Zeng , Xifeng Yan

Designing multi-agent workflows is especially difficult in open-ended scientific settings where tasks lack curated training sets, reliable scalar evaluation metrics, and standardized interfaces between existing tools and agents. We propose…

Artificial Intelligence · Computer Science 2026-05-21 Shuaike Shen , Wenduo Cheng , Shike Wang , Mingqian Ma , Jian Ma

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

Current multimodal large language models (MLLMs) are mainly focused on the understanding and processing of perceptual modalities such as images and videos, while their capability for scientific data understanding remains insufficient. To…

Artificial Intelligence · Computer Science 2026-05-14 Yanjie Li , Lina Yu , Weijun Li , Min Wu , Liping Zhang , Jingyi Liu , Yusong Deng , Mingzhu Wan , Xin Ning

We consider the problem of designing an artificial agent capable of interacting with humans in collaborative dialogue to produce creative, engaging narratives. In this task, the goal is to establish universe details, and to collaborate on…

Human-Computer Interaction · Computer Science 2019-02-01 Kory W. Mathewson , Pablo Samuel Castro , Colin Cherry , George Foster , Marc G. Bellemare

Mental health assessment is crucial for early intervention and effective treatment, yet traditional clinician-based approaches are limited by the shortage of qualified professionals. Recent advances in artificial intelligence have sparked…

Computation and Language · Computer Science 2025-08-18 Jinpeng Hu , Ao Wang , Qianqian Xie , Hui Ma , Zhuo Li , Dan Guo

Testing humanoid robots with users is slow, causes wear, and limits iteration and diversity. Yet screening agents must master conversational timing, prosody, backchannels, and what to attend to in faces and speech for Depression and PTSD.…

Machine Learning · Computer Science 2025-12-11 Filippo Cenacchi , Deborah Richards , Longbing Cao

Reproducing computational research is often assumed to be as simple as rerunning the original code with provided data. In practice, missing packages, fragile file paths, version conflicts, or incomplete logic frequently cause analyses to…

Software Engineering · Computer Science 2026-04-24 Syed Mehtab Hussain Shah , Frank Hopfgartner , Arnim Bleier