Related papers: Curvature-driven pattern formation in biomembranes…
We use a coarse grained molecular model of supported lipid bilayers to study the formation of adhesion domains. We find that this process is a first order phase transition, triggered by a combination of pairwise short range attractive…
Diffusion-driven patterns appear on curved surfaces in many settings, initiated by unstable modes of an underlying Laplacian operator. On a flat surface or perfect sphere, the patterns are degenerate, reflecting translational/rotational…
We study dynamics of a membrane and its matrix regularisation. We present the matrix regularisation for a membrane propagating in a curved space-time geometry in the presence of an arbitrary 3-form field. In the matrix regularisation, we…
Two-way coupled DNS simulation of particle-laden turbulent Couette-flow [1], in the volume fraction regime $\phi>10^{-4}$, showed a discontinuous decrease of turbulence intensity beyond a critical volume fraction…
In this paper, we consider a stochastic version of the Cahn-Hilliard-Brinkman model in a smooth two- or three-dimensional domain with dynamical boundary conditions. The system describes creeping two-phase flows and is basically a coupling…
Motivated to understand the behavior of biological filaments interacting with membranes of various types, we study a theoretical model for the shape and thermodynamics of intrinsically-helical filaments bound to curved membranes. We show…
In this work, we propose a novel phase-field model for the simulation of two-phase flows that is accurate, conservative, bounded, and robust. The proposed model conserves the mass of each of the phases, and results in bounded transport of…
The effect of strong shear flow on highly fluctuating lamellar systems stabilized by intermembrane collisions via the Helfrich interaction is studied. Advection enters the microscopic equation of motion for a single membrane via a…
The difficulties in dealing with discontinuities related to a sharp crack are overcome in the phase-field approach for fracture by modeling the crack as a diffusive object being described by a continuous field having high gradients. The…
A nonlocal interface equation is derived for two-phase fluid flow, with arbitrary wettability and viscosity contrast c=(mu_1-mu_2)/(mu_1+mu_2), in a model porous medium defined as a Hele-Shaw cell with random gap b_0+delta b. Fluctuations…
In this paper, we study a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical potential is replaced by a hyperbolic one. We show that the resulting…
We consider a two-phase Darcy flow in a fractured and deformable porous medium for which the fractures are described as a network of planar surfaces leading to so-called hybrid-dimensional models. The fractures are assumed open and filled…
This paper addresses the approximation of the mean curvature flow of thin structures for which classical phase field methods are not suitable. By thin structures, we mean surfaces that are not domain boundaries, typically higher codimension…
The paper presents a complete research cycle comprising continuum-based modeling, computational framework development, and validation setup to predict phase separation and surface hydrodynamics in lipid bilayer membranes. We starting with…
In this paper, a phase-field model is introduced to describe the evolution of a deformable, self-propelled object driven by surface-tension effects. The model couples an Allen-Cahn-type equation, which distinguishes the body from the…
Biomolecular condensates are formed via liquid-liquid phase separation of proteins, often together with nucleic acids, typically driven by interactions between low-affinity binding sites. The computational study of such condensates that…
A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…
We present simulations of granular flows in a modified Couette cell, using a continuum model recently proposed for dense granular flows. Based on a friction coefficient, which depends on an inertial number, the model captures the positions…
We investigate a multiphase Cahn-Hilliard model for tumor growth with general source terms. The multiphase approach allows us to consider multiple cell types and multiple chemical species (oxygen and/or nutrients) that are consumed by the…
We consider generalized gradient systems in Banach spaces whose evolutions are generated by the interplay between an energy functional and a dissipation potential. We focus on the case in which the dual dissipation potential is given by a…