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We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

Methodology · Statistics 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

Genetic sequence data of pathogens are increasingly used to investigate transmission dynamics in both endemic diseases and disease outbreaks; such research can aid in development of appropriate interventions and in design of studies to…

Quantitative Methods · Quantitative Biology 2018-01-24 Hesam Montazeri , Susan Little , Niko Beerenwinkel , Victor DeGruttola

Interval-censored data analysis is important in biomedical statistics for any type of time-to-event response where the time of response is not known exactly, but rather only known to occur between two assessment times. Many clinical trials…

Methodology · Statistics 2019-06-12 Weichi Yao , Halina Frydman , Jeffrey S. Simonoff

Predictions of fatalities from violent conflict on the PRIO-GRID-month (pgm) level are characterized by high levels of uncertainty, limiting their usefulness in practical applications. We discuss the two main sources of uncertainty for this…

Applications · Statistics 2026-03-13 Daniel Mittermaier , Tobias Bohne , Martin Hofer , Daniel Racek

This paper is concerned with the reliable inference of optimal tree-approximations to the dependency structure of an unknown distribution generating data. The traditional approach to the problem measures the dependency strength between…

Machine Learning · Computer Science 2007-07-16 Marco Zaffalon , Marcus Hutter

This paper presents a novel extension of the edge-based compartmental model for epidemics with arbitrary distributions of transmission and recovery times. Using the message passing approach we also derive a new pairwise-like model for…

Quantitative Methods · Quantitative Biology 2016-11-15 N. Sherborne , J. C. Miller , K. B. Blyuss , I. Z. Kiss

The epidemic spreading of a disease can be described by a contact network whose nodes are persons or centers of contagion and links heterogeneous relations among them. We provide a procedure to identify multiple sources of an outbreak or…

Mathematical Physics · Physics 2012-11-13 Vincenzo Fioriti , Marta Chinnici

Random Forest (RF) is an ensemble supervised machine learning technique that was developed by Breiman over a decade ago. Compared with other ensemble techniques, it has proved its accuracy and superiority. Many researchers, however, believe…

Machine Learning · Computer Science 2015-03-18 Khaled Fawagreh , Mohamad Medhat Gaber , Eyad Elyan

We introduce random survival forests, a random forests method for the analysis of right-censored survival data. New survival splitting rules for growing survival trees are introduced, as is a new missing data algorithm for imputing missing…

Applications · Statistics 2008-11-12 Hemant Ishwaran , Udaya B. Kogalur , Eugene H. Blackstone , Michael S. Lauer

In prediction tasks with multi-class outcomes, identifying covariates specifically associated with one or more outcome classes can be important. Conventional variable importance measures (VIMs) from random forests (RFs), like permutation…

Machine Learning · Statistics 2024-09-16 Roman Hornung , Alexander Hapfelmeier

We consider a continuous-time Markov chain model of SIR disease dynamics with two levels of mixing. For this so-called stochastic households model, we provide two methods for inferring the model parameters---governing within-household…

Populations and Evolution · Quantitative Biology 2018-02-07 James N. Walker , Joshua V. Ross , Andrew J. Black

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

Epidemic surveillance is a challenging task, especially when crucial data is fragmented across institutions and data custodians are unable or unwilling to share it. This study aims to explore the feasibility of a simple federated…

Applications · Statistics 2024-09-17 Ruiqi Lyu , Roni Rosenfeld , Bryan Wilder

Left-truncated survival data commonly arise in prevalent cohort studies, where only individuals who have experienced disease onset and survived until enrollment in the study. When the onset process follows a stationary Poisson process, the…

Methodology · Statistics 2025-12-23 Jinwoo Lee , Donghwan Lee , Hyunwoo Lee , Jiyu Sun

Tree-based methods are popular nonparametric tools in studying time-to-event outcomes. In this article, we introduce a novel framework for survival trees and ensembles, where the trees partition the dynamic survivor population and can…

Methodology · Statistics 2020-01-14 Yifei Sun , Sy Han Chiou , Mei-Cheng Wang

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

Methodology · Statistics 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li

Epidemic propagation on networks represents an important departure from traditional massaction models. However, the high-dimensionality of the exact models poses a challenge to both mathematical analysis and parameter inference. By using…

Quantitative Methods · Quantitative Biology 2023-02-07 István Z. Kiss , Luc Berthouze , Wasiur R. KhudaBukhsh

The behavior of ecological systems mainly relies on the interactions between the species it involves. We consider the problem of inferring the species interaction network from abundance data. To be relevant, any network inference…

Applications · Statistics 2019-10-29 Raphaëlle Momal , Stéphane Robin , Christophe Ambroise

We introduce a unified framework for random forest prediction error estimation based on a novel estimator of the conditional prediction error distribution function. Our framework enables simple plug-in estimation of key prediction…

Machine Learning · Statistics 2021-03-04 Benjamin Lu , Johanna Hardin

A compartmental deterministic model that allows (1) immunity from two stages of infection and carriage, and (2) disease induced death, is used in studying the dynamics of meningitis epidemic process in a closed population. It allows for…

Populations and Evolution · Quantitative Biology 2023-04-04 S. J Yaga , F. W. O Saporu
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