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Related papers: The Human Brain as a Combinatorial Complex

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We propose a new framework, called Hierarchical Multi-resolution Mesh Networks (HMMNs), which establishes a set of brain networks at multiple time resolutions of fMRI signal to represent the underlying cognitive process. The suggested…

Neural and Evolutionary Computing · Computer Science 2017-01-13 Itir Onal Ertugrul , Mete Ozay , Fatos Tunay Yarman Vural

Networks of interconnected neurons display diverse patterns of collective activity. Relating this collective activity to the network's connectivity structure is a key goal of computational neuroscience. We approach this question for…

Neurons and Cognition · Quantitative Biology 2025-06-09 Caitlin Lienkaemper , Gabriel Koch Ocker

Graph Convolutional Networks (GCNs) have recently been shown to be quite successful in modeling graph-structured data. However, the primary focus has been on handling simple undirected graphs. Multi-relational graphs are a more general and…

Machine Learning · Computer Science 2020-01-22 Shikhar Vashishth , Soumya Sanyal , Vikram Nitin , Partha Talukdar

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Complex prediction models such as deep learning are the output from fitting machine learning, neural networks, or AI models to a set of training data. These are now standard tools in science. A key challenge with the current generation of…

Machine Learning · Computer Science 2022-10-21 Meng Liu , Tamal K. Dey , David F. Gleich

Applying network science approaches to investigate the functions and anatomy of the human brain is prevalent in modern medical imaging analysis. Due to the complex network topology, for an individual brain, mining a discriminative network…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Wen Zhang , Liang Zhan , Paul Thompson , Yalin Wang

Graphs serve as powerful tools for modeling pairwise interactions in diverse fields such as biology, material science, and social networks. However, they inherently overlook interactions involving more than two entities. Simplicial…

Algebraic Topology · Mathematics 2024-12-05 Xiang Liu , Ran Liu , Jingyan Li , Rongling Wu , Jie Wu

Accurately characterizing higher-order interactions of brain regions and extracting interpretable organizational patterns from Functional Magnetic Resonance Imaging data is crucial for brain disease diagnosis. Current graph-based deep…

Neurons and Cognition · Quantitative Biology 2026-03-16 Dengyi Zhao , Zhiheng Zhou , Guiying Yan , Dongxiao Yu , Xingqin Qi

Predicting cognition from neuroimaging data in healthy individuals offers insights into the neural mechanisms underlying cognitive abilities, with potential applications in precision medicine and early detection of neurological and…

Machine Learning · Computer Science 2025-07-29 Jagruti Patel , Mikkel Schöttner , Thomas A. W. Bolton , Patric Hagmann

Graph neural networks (GNNs) have emerged as a powerful tool for solving combinatorial optimization problems (COPs), exhibiting state-of-the-art performance in both graph-structured and non-graph-structured domains. However, existing…

Artificial Intelligence · Computer Science 2024-06-21 Yaochu Jin , Xueming Yan , Shiqing Liu , Xiangyu Wang

The successful integration of graph neural networks into recommender systems (RSs) has led to a novel paradigm in collaborative filtering (CF), graph collaborative filtering (graph CF). By representing user-item data as an undirected,…

The comorbidities of hypertension impose a heavy burden on patients and society. Early identification is necessary to prompt intervention, but it remains a challenging task. This study aims to address this challenge by combining joint graph…

Machine Learning · Computer Science 2025-06-13 Leming Zhou , Zuo Wang , Zhixuan Duan

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

One of the most well-established tools for modeling the brain as a complex system is the functional connectivity network, which examines the correlations between pairs of interacting brain regions. While powerful, the network model is…

Information Theory · Computer Science 2022-06-15 Thomas F. Varley , Maria Pope , Joshua Faskowitz , Olaf Sporns

Artificial intelligence (AI) systems, and Large Language Models (LLMs) in particular, are increasingly employed for creative tasks like scientific idea generation, constituting a form of generalization from training data unaddressed by…

Artificial Intelligence · Computer Science 2026-01-05 Samuel Schapiro , Sumuk Shashidhar , Alexi Gladstone , Jonah Black , Royce Moon , Dilek Hakkani-Tur , Lav R. Varshney

In recent years, there has been a growing interest in using learning-based approaches for solving combinatorial problems, either in an end-to-end manner or in conjunction with traditional optimization algorithms. In both scenarios, the…

Machine Learning · Computer Science 2024-03-14 Léo Boisvert , Hélène Verhaeghe , Quentin Cappart

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

Machine Learning · Statistics 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

Multiplex networks are complex graph structures in which a set of entities are connected to each other via multiple types of relations, each relation representing a distinct layer. Such graphs are used to investigate many complex…

Scientific inquiry requires systems-level reasoning that integrates heterogeneous experimental data, cross-domain knowledge, and mechanistic evidence into coherent explanations. While Large Language Models (LLMs) offer inferential…

Artificial Intelligence · Computer Science 2026-01-09 Isabella A. Stewart , Markus J. Buehler

Complementary Learning Systems (CLS) theory suggests that the brain uses a 'neocortical' and a 'hippocampal' learning system to achieve complex behavior. These two systems are complementary in that the 'neocortical' system relies on slow…

Neurons and Cognition · Quantitative Biology 2019-05-08 Sam Blakeman , Denis Mareschal