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The adoption of deep learning in healthcare is hindered by their "black box" nature. In this paper, we explore the RETAIN architecture for the task of glusose forecasting for diabetic people. By using a two-level attention mechanism, the…

Machine Learning · Computer Science 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Deep neural networks are a key component of behavior prediction and motion generation for self-driving cars. One of their main drawbacks is a lack of transparency: they should provide easy to interpret rationales for what triggers certain…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Jinkyu Kim , Mayank Bansal

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Yidong Zhu , Nadia B Aimandi , Mohammad Arif Ul Alam

In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 diabetes. We consider three families of sequence models based on LSTM, GRU, and…

Machine Learning · Computer Science 2026-03-31 Hai Siong Tan , Rafe McBeth

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

Machine Learning · Computer Science 2026-04-27 Beyza Cinar , Maria Maleshkova

We consider the question of 30-minute prediction of blood glucose levels measured by continuous glucose monitoring devices, using clinical data. While most studies of this nature deal with one patient at a time, we take a certain percentage…

Machine Learning · Computer Science 2017-07-20 H. N. Mhaskar , S. V. Pereverzyev , M. D. van der Walt

Background and objective: Diabetes is one of the four leading causes of death worldwide, necessitating daily blood glucose monitoring. While sweat offers a promising non-invasive alternative for glucose monitoring, its application remains…

Quantitative Methods · Quantitative Biology 2024-12-05 Xiaoyu Yin , Elisabetta Peri , Eduard Pelssers , Jaap den Toonder , Lisa Klous , Hein Daanen , Massimo Mischi

Diabetes is a global health burden, and early detection is critical for timely intervention. This study explores a non-invasive, data-driven framework to identify individuals at risk of diabetes using Volatile Organic Compounds (VOCs) and…

Machine Learning · Computer Science 2026-05-22 Varsha Sharma , Prasanta K. Guha , Avik Ghose

Diabetic retinopathy (DR) is one of the leading causes of blindness in the working-age population of developed countries, caused by a side effect of diabetes that reduces the blood supply to the retina. Deep neural networks have been widely…

Computer Vision and Pattern Recognition · Computer Science 2022-08-05 Jose Miguel Arrieta Ramos , Oscar Perdómo , Fabio A. González

The dead-in-bed syndrome describes the sudden and unexplained death of young individuals with Type 1 Diabetes (T1D) without prior long-term complications. One leading hypothesis attributes this phenomenon to nocturnal hypoglycemia (NH), a…

Machine Learning · Computer Science 2025-04-15 Marco Voegeli , Sonia Laguna , Heike Leutheuser , Marc Pfister , Marie-Anne Burckhardt , Julia E Vogt

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…

Computer Vision and Pattern Recognition · Computer Science 2019-02-27 Kezhi Li , John Daniels , Chengyuan Liu , Pau Herrero , Pantelis Georgiou

The mathematical modelling of biological systems has historically followed one of two approaches: comprehensive and minimal. In comprehensive models, the involved biological pathways are modelled independently, then brought together as an…

Dynamical Systems · Mathematics 2021-11-16 Eric Ng , Jaycee Morgan Kaufman , Lennaert van Veen , Yan Fossat

In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…

Quantitative Methods · Quantitative Biology 2022-09-22 M. Sirlanci , M. E. Levine , C. C. Low Wang , D. J. Albers , A. M. Stuart

Automatic depression detection from doctor-patient conversations has gained momentum thanks to the availability of public corpora and advances in language modeling. However, interpretability remains limited: strong performance is often…

The classification of diabetes and prediabetes by static glucose thresholds obscures the pathophysiological dysglycemia heterogeneity, primarily driven by insulin resistance (IR), beta-cell dysfunction, and incretin deficiency. This review…

Machine Learning · Computer Science 2025-11-07 Ahmed A. Metwally , Heyjun Park , Yue Wu , Tracey McLaughlin , Michael P. Snyder

In this paper, we explore different deep learning based approaches to detect driver fatigue. Drowsy driving results in approximately 72,000 crashes and 44,000 injuries every year in the US and detecting drowsiness and alerting the driver…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Ken Alparslan , Yigit Alparslan , Matthew Burlick

This paper proposes a robust control design method using reinforcement-learning for controlling partially-unknown dynamical systems under uncertain conditions. The method extends the optimal reinforcement-learning algorithm with a new…

Systems and Control · Electrical Eng. & Systems 2020-04-17 Phuong D. Ngo , Fred Godtliebsen

Causal abstraction techniques such as Interchange Intervention Training (IIT) have been proposed to infuse neural network with expert knowledge encoded in causal models, but their application to real-world problems remains limited. This…

Machine Learning · Computer Science 2025-03-19 Ana Esponera , Giovanni Cinà

A deep learning network was used to predict future blood glucose levels, as this can permit diabetes patients to take action before imminent hyperglycaemia and hypoglycaemia. A sequential model with one long-short-term memory (LSTM) layer,…

Machine Learning · Computer Science 2018-09-12 Qingnan Sun , Marko V. Jankovic , Lia Bally , Stavroula G. Mougiakakou