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Computational phantoms are widely used in medical imaging research, yet current systems to generate controlled, clinically meaningful anatomical variations remain limited. We present AbdomenGen, a sequential volume-conditioned diffusion…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yubraj Bhandari , Lavsen Dahal , Paul Segars , Joseph Y. Lo

Intracellular protein patterns regulate many vital cellular functions, such as the processing of spatiotemporal information or the control of shape deformations. To do so, pattern-forming systems can be sensitive to the cell geometry by…

Biological Physics · Physics 2024-05-15 Tom Burkart , Benedikt J. Müller , Erwin Frey

We introduce a new diffusion-based approach for shape completion on 3D range scans. Compared with prior deterministic and probabilistic methods, we strike a balance between realism, multi-modality, and high fidelity. We propose DiffComplete…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Ruihang Chu , Enze Xie , Shentong Mo , Zhenguo Li , Matthias Nießner , Chi-Wing Fu , Jiaya Jia

Diffusion models have become a leading approach for high-fidelity medical image synthesis. However, most existing methods for 3D medical image generation rely on convolutional U-Net backbones within latent diffusion frameworks. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Marvin Seyfarth , Salman Ul Hassan Dar , Yannik Frisch , Philipp Wild , Norbert Frey , Florian André , Sandy Engelhardt

Topological Data Analysis (TDA) can be used to detect and characterize holes in an image, such as zero-dimensional holes (connected components) or one-dimensional holes (loops). However, there is currently no widely accepted statistical…

Methodology · Statistics 2025-08-26 Susan Glenn , Jessi Cisewski-Kehe , Jun Zhu , William M Bement

We present a new method for the statistical process control of lattice structures using tools from Topological Data Analysis. Motivated by applications in additive manufacturing, such as aerospace components and biomedical implants, where…

Methodology · Statistics 2025-10-15 Yulin An , Xueqi Zhao , Enrique del Castillo

Comparing mathematical models offers a means to evaluate competing scientific theories. However, exact methods of model calibration are not applicable to many probabilistic models which simulate high-dimensional spatio-temporal data.…

Quantitative Methods · Quantitative Biology 2026-01-13 Robert A McDonald , Helen M Byrne , Heather A Harrington , Thomas Thorne , Bernadette J Stolz

Structural topology optimization, which aims to find the optimal physical structure that maximizes mechanical performance, is vital in engineering design applications in aerospace, mechanical, and civil engineering. Generative adversarial…

Machine Learning · Computer Science 2022-12-07 François Mazé , Faez Ahmed

Recently, diffusion models have achieved great success in image synthesis. However, when it comes to the layout-to-image generation where an image often has a complex scene of multiple objects, how to make strong control over both the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Guangcong Zheng , Xianpan Zhou , Xuewei Li , Zhongang Qi , Ying Shan , Xi Li

Existing generative approaches for guided image synthesis of multi-object scenes typically rely on 2D controls in the image or text space. As a result, these methods struggle to maintain and respect consistent three-dimensional geometric…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Léopold Maillard , Tom Durand , Adrien Ramanana Rahary , Maks Ovsjanikov

Many natural shapes have most of their characterizing features concentrated over a few regions in space. For example, humans and animals have distinctive head shapes, while inorganic objects like chairs and airplanes are made of…

Computer Vision and Pattern Recognition · Computer Science 2022-06-27 Marco Pegoraro , Simone Melzi , Umberto Castellani , Riccardo Marin , Emanuele Rodolà

Controllable spherical panoramic image generation holds substantial applicative potential across a variety of domains.However, it remains a challenging task due to the inherent spherical distortion and geometry characteristics, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Tao Wu , Xuewei Li , Zhongang Qi , Di Hu , Xintao Wang , Ying Shan , Xi Li

The context of this paper is the use of formal methods for topology-based geometric modelling. Topology-based geometric modelling deals with objects of various dimensions and shapes. Usually, objects are defined by a graph-based topological…

Graphics · Computer Science 2011-02-15 Thomas Bellet , Agnès Arnould , Pascale Le Gall

Topology in photonics comes in two distinct flavors: global and local. Global topology considers invariants that are obtained by integrating over the energy band, whereas local topology considers defects, typically vortices, in the…

Optics · Physics 2026-01-15 Kristian Arjas , Grazia Salerno , Päivi Törmä

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Topology is a powerful tool for categorizing magnetization textures by defining a topological index in both two-dimensional (2D) systems, such as thin films or curved surfaces, and in 3D bulk systems. In the emerging field of 3D…

Large-scale generative models have demonstrated impressive capabilities in producing visually compelling images, with increasing applications in medical imaging. However, they continue to grapple with hallucination challenges and the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Anees Ur Rehman Hashmi , Ibrahim Almakky , Mohammad Areeb Qazi , Santosh Sanjeev , Vijay Ram Papineni , Jagalpathy Jagdish , Mohammad Yaqub

Text-to-image diffusion models have revolutionized image synthesis and editing, but precise control over stylistic attributes remains a challenge, often causing unintended content modifications. We propose an approach for fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Max Reimann , Benito Buchheim , Jürgen Döllner

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Stochastically evolving geometric systems are studied in shape analysis and computational anatomy for modelling random evolutions of human organ shapes. The notion of geodesic paths between shapes is central to shape analysis and has a…

Numerical Analysis · Mathematics 2022-12-01 Alexis Arnaudon , Frank van der Meulen , Moritz Schauer , Stefan Sommer