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Treatment decisions for brain metastatic disease rely on knowledge of the primary organ site, and currently made with biopsy and histology. Here we develop a novel deep learning approach for accurate non-invasive digital histology with…

In this paper, we present a novel approach for segmenting pediatric brain tumors using a deep learning architecture, inspired by expert radiologists' segmentation strategies. Our model delineates four distinct tumor labels and is…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Max Bengtsson , Elif Keles , Gorkem Durak , Syed Anwar , Yuri S. Velichko , Marius G. Linguraru , Angela J. Waanders , Ulas Bagci

Differentiating true tumor progression (TP) from treatment-related pseudoprogression (PsP) in glioblastoma remains challenging, especially at early follow-up. We present the first stage-specific, cross-sectional benchmarking of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Wenhao Guo , Golrokh Mirzaei

We describe the design and results from the BraTS 2023 Intracranial Meningioma Segmentation Challenge. The BraTS Meningioma Challenge differed from prior BraTS Glioma challenges in that it focused on meningiomas, which are typically benign…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Dominic LaBella , Ujjwal Baid , Omaditya Khanna , Shan McBurney-Lin , Ryan McLean , Pierre Nedelec , Arif Rashid , Nourel Hoda Tahon , Talissa Altes , Radhika Bhalerao , Yaseen Dhemesh , Devon Godfrey , Fathi Hilal , Scott Floyd , Anastasia Janas , Anahita Fathi Kazerooni , John Kirkpatrick , Collin Kent , Florian Kofler , Kevin Leu , Nazanin Maleki , Bjoern Menze , Maxence Pajot , Zachary J. Reitman , Jeffrey D. Rudie , Rachit Saluja , Yury Velichko , Chunhao Wang , Pranav Warman , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Syed Muhammad Anwar , Timothy Bergquist , Sully Francis Chen , Verena Chung , Rong Chai , Gian-Marco Conte , Farouk Dako , James Eddy , Ivan Ezhov , Nastaran Khalili , Juan Eugenio Iglesias , Zhifan Jiang , Elaine Johanson , Koen Van Leemput , Hongwei Bran Li , Marius George Linguraru , Xinyang Liu , Aria Mahtabfar , Zeke Meier , Ahmed W. Moawad , John Mongan , Marie Piraud , Russell Takeshi Shinohara , Walter F. Wiggins , Aly H. Abayazeed , Rachel Akinola , András Jakab , Michel Bilello , Maria Correia de Verdier , Priscila Crivellaro , Christos Davatzikos , Keyvan Farahani , John Freymann , Christopher Hess , Raymond Huang , Philipp Lohmann , Mana Moassefi , Matthew W. Pease , Phillipp Vollmuth , Nico Sollmann , David Diffley , Khanak K. Nandolia , Daniel I. Warren , Ali Hussain , Pascal Fehringer , Yulia Bronstein , Lisa Deptula , Evan G. Stein , Mahsa Taherzadeh , Eduardo Portela de Oliveira , Aoife Haughey , Marinos Kontzialis , Luca Saba , Benjamin Turner , Melanie M. T. Brüßeler , Shehbaz Ansari , Athanasios Gkampenis , David Maximilian Weiss , Aya Mansour , Islam H. Shawali , Nikolay Yordanov , Joel M. Stein , Roula Hourani , Mohammed Yahya Moshebah , Ahmed Magdy Abouelatta , Tanvir Rizvi , Klara Willms , Dann C. Martin , Abdullah Okar , Gennaro D'Anna , Ahmed Taha , Yasaman Sharifi , Shahriar Faghani , Dominic Kite , Marco Pinho , Muhammad Ammar Haider , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Michelle Alonso-Basanta , Javier Villanueva-Meyer , Andreas M. Rauschecker , Ayman Nada , Mariam Aboian , Adam E. Flanders , Benedikt Wiestler , Spyridon Bakas , Evan Calabrese

Detection of brain tumor using a segmentation based approach is critical in cases, where survival of a subject depends on an accurate and timely clinical diagnosis. Gliomas are the most commonly found tumors having irregular shape and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-16 Saddam Hussain , Syed Muhammad Anwar , Muhammad Majid

Deep learning motivated by convolutional neural networks has been highly successful in a range of medical imaging problems like image classification, image segmentation, image synthesis etc. However for validation and interpretability, not…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abhinav Sagar

Breast cancer is a highly heterogeneous disease with diverse molecular profiles. The PAM50 gene signature is widely recognized as a standard for classifying breast cancer into intrinsic subtypes, enabling more personalized treatment…

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

Glioblastoma is a common brain malignancy that tends to occur in older adults and is almost always lethal. The effectiveness of chemotherapy, being the standard treatment for most cancer types, can be improved if a particular genetic…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Numan Saeed , Shahad Hardan , Kudaibergen Abutalip , Mohammad Yaqub

Glioma is the most deadly brain tumor with high mortality. Treatment planning by human experts depends on the proper diagnosis of physical symptoms along with Magnetic Resonance(MR) image analysis. Highly variability of a brain tumor in…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Rupal Agravat , Mehul S Raval

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Gliomas are the most common malignant brain tumourswith intrinsic heterogeneity. Accurate segmentation of gliomas and theirsub-regions on multi-parametric magnetic resonance images (mpMRI)is of great clinical importance, which defines…

Image and Video Processing · Electrical Eng. & Systems 2019-11-21 Shuo Wang , Chengliang Dai , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

Brain tumor image segmentation is a challenging research topic in which deep-learning models have presented the best results. However, the traditional way of training those models from many pre-annotated images leaves several unanswered…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Matheus A. Cerqueira , Flávia Sprenger , Bernardo C. A. Teixeira , Alexandre X. Falcão

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

Glioblastoma, a highly aggressive brain tumor, poses major challenges due to its poor prognosis and high morbidity rates. Partial differential equation-based models offer promising potential to enhance therapeutic outcomes by simulating…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Zeineb Haouari , Jonas Weidner , Yeray Martin-Ruisanchez , Ivan Ezhov , Aswathi Varma , Daniel Rueckert , Bjoern Menze , Benedikt Wiestler

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

Monitoring of Diffuse Intrinsic Pontine Glioma (DIPG) and Diffuse Midline Glioma (DMG) brain tumors in pediatric patients is key for assessment of treatment response. Response Assessment in Pediatric Neuro-Oncology (RAPNO) guidelines…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Timothy Mulvany , Daniel Griffiths-King , Jan Novak , Heather Rose