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Pyserini is an easy-to-use Python toolkit that supports replicable IR research by providing effective first-stage retrieval in a multi-stage ranking architecture. Our toolkit is self-contained as a standard Python package and comes with…

Information Retrieval · Computer Science 2021-02-22 Jimmy Lin , Xueguang Ma , Sheng-Chieh Lin , Jheng-Hong Yang , Ronak Pradeep , Rodrigo Nogueira

Btrim is a fast and lightweight software to trim adapters and low quality regions in reads from ultra high-throughput next-generation sequencing machines. It also can reliably identify barcodes and assign the reads to the original samples.…

Genomics · Quantitative Biology 2024-05-28 Yong Kong

Data discretization, also known as binning, is a frequently used technique in computer science, statistics, and their applications to biological data analysis. We present a new method for the discretization of real-valued data into a finite…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Elena S. Dimitrova , John J. McGee , Reinhard C. Laubenbacher

Deep Learning (DL) workloads have rapidly increased in popularity in enterprise clusters and several new cluster schedulers have been proposed in recent years to support these workloads. With rapidly evolving DL workloads, it is challenging…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-12-21 Saurabh Agarwal , Amar Phanishayee , Shivaram Venkataraman

Cluster deletion is an NP-hard graph clustering objective with applications in computational biology and social network analysis, where the goal is to delete a minimum number of edges to partition a graph into cliques. We first provide a…

Data Structures and Algorithms · Computer Science 2024-04-26 Vicente Balmaseda , Ying Xu , Yixin Cao , Nate Veldt

Next generation sequencing of B cell receptor (BCR) repertoires has become a ubiquitous tool for understanding the antibody-mediated immune response: it is now common to have large volumes of sequence data coding for both the heavy and…

Genomics · Quantitative Biology 2023-01-11 Duncan K. Ralph , Frederick A. Matsen

Over the past few decades, a vast amount of information on the structure of atomic nuclei has been collected, compiled, and evaluated. Accurate and reliable data are essential for the understanding of the behavior of atomic nuclei.…

Computational Physics · Physics 2024-08-21 Jérémie Dudouet , Diego Gruyer

Subgraph discovery in a single data graph---finding subsets of vertices and edges satisfying a user-specified criteria---is an essential and general graph analytics operation with a wide spectrum of applications. Depending on the criteria,…

Databases · Computer Science 2018-07-25 Aparna Joshi , Yu Zhang , Petko Bogdanov , Jeong-Hyon Hwang

This paper presents a new, parallel implementation of clustering and demonstrates its utility in greatly speeding up the process of identifying homologous proteins. Clustering is a technique to reduce the number of comparison needed to find…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-29 Stuart Byma , Akash Dhasade , Adrian Altenhoff , Christophe Dessimoz , James R. Larus

Learned indexes are promising to replace traditional tree-based indexes. They typically employ machine learning models to efficiently predict target positions in strictly sorted linear arrays. However, the strict sorted order 1)…

Databases · Computer Science 2025-02-18 Huibing Dong , Wenlong Wang , Chun Liu , David Du

Biclustering is a class of techniques that simultaneously clusters the rows and columns of a matrix to sort heterogeneous data into homogeneous blocks. Although many algorithms have been proposed to find biclusters, existing methods suffer…

Machine Learning · Statistics 2020-02-11 Michelle N. Ngo , Dustin S. Pluta , Alexander N. Ngo , Babak Shahbaba

Assessing the correctness of genome assemblies is an important step in any genome project. Several methods exist, but most are computationally intensive and, in some cases, inappropriate. Here I present baa.pl, a fast and easy-to-use…

Genomics · Quantitative Biology 2014-02-10 Joseph F. Ryan

Binarization is an attractive strategy for implementing lightweight Deep Convolutional Neural Networks (CNNs). Despite the unquestionable savings offered, memory footprint above all, it may induce an excessive accuracy loss that prevents a…

Machine Learning · Computer Science 2019-12-30 Luca Mocerino , Andrea Calimera

This paper presents a novel method for efficient image retrieval, based on a simple and effective hashing of CNN features and the use of an indexing structure based on Bloom filters. These filters are used as gatekeepers for the database of…

Multimedia · Computer Science 2016-05-04 Andrea Salvi , Simone Ercoli , Marco Bertini , Alberto Del Bimbo

Answering complex questions over knowledge bases (KB-QA) faces huge input data with billions of facts, involving millions of entities and thousands of predicates. For efficiency, QA systems first reduce the answer search space by…

Information Retrieval · Computer Science 2022-04-05 Philipp Christmann , Rishiraj Saha Roy , Gerhard Weikum

Generating the hash values of short subsequences, called seeds, enables quickly identifying similarities between genomic sequences by matching seeds with a single lookup of their hash values. However, these hash values can be used only for…

Binarized neural networks, or BNNs, show great promise in edge-side applications with resource limited hardware, but raise the concerns of reduced accuracy. Motivated by the complex neural networks, in this paper we introduce complex…

Neural and Evolutionary Computing · Computer Science 2021-04-21 Yanfei Li , Tong Geng , Ang Li , Huimin Yu

Developers perform online sensemaking on a daily basis, such as researching and choosing libraries and APIs. Prior research has introduced tools that help developers capture information from various sources and organize it into structures…

Software Engineering · Computer Science 2022-02-07 Michael Xieyang Liu , Aniket Kittur , Brad A. Myers

Interpreting samples from likelihood or posterior probability density functions is rarely as straightforward as it seems it should be. Producing publication-quality graphics of these distributions is often similarly painful. In this short…

Data Analysis, Statistics and Probability · Physics 2016-11-18 Pat Scott

Understanding the base pairing of an RNA sequence provides insight into its molecular structure.By mining suboptimal sampling data, RNAprofiling 1.0 identifies the dominant helices in low-energy secondary structures as features, organizes…

Biomolecules · Quantitative Biology 2023-03-29 Forrest Hurley , Christine Heitsch