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Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Skin cancer detection through dermoscopy image analysis is a critical task. However, existing models used for this purpose often lack interpretability and reliability, raising the concern of physicians due to their black-box nature. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Miguel Correia , Alceu Bissoto , Carlos Santiago , Catarina Barata

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

When we are faced with challenging image classification tasks, we often explain our reasoning by dissecting the image, and pointing out prototypical aspects of one class or another. The mounting evidence for each of the classes helps us…

Machine Learning · Computer Science 2020-01-01 Chaofan Chen , Oscar Li , Chaofan Tao , Alina Jade Barnett , Jonathan Su , Cynthia Rudin

Neural networks have greatly boosted performance in computer vision by learning powerful representations of input data. The drawback of end-to-end training for maximal overall performance are black-box models whose hidden representations…

Computer Vision and Pattern Recognition · Computer Science 2020-04-29 Patrick Esser , Robin Rombach , Björn Ommer

The black-box nature of deep learning models prevents them from being completely trusted in domains like biomedicine. Most explainability techniques do not capture the concept-based reasoning that human beings follow. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Avinash Kori , Parth Natekar , Ganapathy Krishnamurthi , Balaji Srinivasan

Prototype-based interpretability methods provide intuitive explanations of model prediction by comparing samples to a reference set of memorized exemplars or typical representatives in terms of similarity. In the field of sequential data…

Machine Learning · Computer Science 2023-03-20 Yifei Zhang , Neng Gao , Cunqing Ma

Recent developments in single-cell omics technologies have enabled the quantification of molecular profiles in individual cells at an unparalleled resolution. Deep learning, a rapidly evolving sub-field of machine learning, has instilled a…

Genomics · Quantitative Biology 2024-01-17 Manoj M Wagle , Siqu Long , Carissa Chen , Chunlei Liu , Pengyi Yang

Deep learning methods usually require a large amount of training data and lack interpretability. In this paper, we propose a novel knowledge distillation and model interpretation framework for medical image classification that jointly…

Computer Vision and Pattern Recognition · Computer Science 2022-01-13 Thanh Nguyen-Duc , He Zhao , Jianfei Cai , Dinh Phung

Despite the success of deep learning in dermoscopy image analysis, its inherent black-box nature hinders clinical trust, motivating the use of prototypical networks for case-based visual transparency. However, inevitable selection bias in…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Junhao Jia , Yueyi Wu , Huangwei Chen , Haodong Jing , Haishuai Wang , Jiajun Bu , Lei Wu

Recent applications of deep convolutional neural networks in medical imaging raise concerns about their interpretability. While most explainable deep learning applications use post hoc methods (such as GradCAM) to generate feature…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Yuanyuan Wei , Roger Tam , Xiaoying Tang

Deep learning models show significant potential for advancing AI-assisted medical diagnostics, particularly in detecting lung cancer through medical image modalities such as chest X-rays. However, the black-box nature of these models poses…

Machine Learning · Computer Science 2025-03-31 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

How do the neural networks distinguish two images? It is of critical importance to understand the matching mechanism of deep models for developing reliable intelligent systems for many risky visual applications such as surveillance and…

Computer Vision and Pattern Recognition · Computer Science 2021-08-13 Wenliang Zhao , Yongming Rao , Ziyi Wang , Jiwen Lu , Jie Zhou

Deep neural networks have been widely used in text classification. However, it is hard to interpret the neural models due to the complicate mechanisms. In this work, we study the interpretability of a variant of the typical text…

Computation and Language · Computer Science 2019-10-25 Hao Cheng , Xiaoqing Yang , Zang Li , Yanghua Xiao , Yucheng Lin

Remote screening of respiratory diseases has been widely studied as a non-invasive and early instrument for diagnosis purposes, especially in the pandemic. The respiratory sound classification task has been realized with numerous deep…

Sound · Computer Science 2022-02-08 Zhao Ren , Thanh Tam Nguyen , Wolfgang Nejdl

The interpretability of deep neural networks has become a subject of great interest within the medical and healthcare domain. This attention stems from concerns regarding transparency, legal and ethical considerations, and the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Mahbub Ul Alam , Jaakko Hollmén , Jón Rúnar Baldvinsson , Rahim Rahmani

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

We propose a new method to count objects of specific categories that are significantly smaller than the ground sampling distance of a satellite image. This task is hard due to the cluttered nature of scenes where different object categories…

Computer Vision and Pattern Recognition · Computer Science 2018-09-21 Andres C. Rodriguez , Jan D. Wegner

We propose a novel perspective to understand deep neural networks in an interpretable disentanglement form. For each semantic class, we extract a class-specific functional subnetwork from the original full model, with compressed structure…

Machine Learning · Computer Science 2019-10-08 Yulong Wang , Xiaolin Hu , Hang Su

Part-prototype models are explainable-by-design image classifiers, and a promising alternative to black box AI. This paper explores the applicability and potential of interpretable machine learning, in particular PIP-Net, for automated…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Meike Nauta , Johannes H. Hegeman , Jeroen Geerdink , Jörg Schlötterer , Maurice van Keulen , Christin Seifert
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