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The identification and quantification of markers in medical images is critical for diagnosis, prognosis and management of patients in clinical practice. Supervised- or weakly supervised training enables the detection of findings that are…

Deep neural networks are capable of learning powerful representations to tackle complex vision tasks but expose undesirable properties like the over-fitting issue. To this end, regularization techniques like image augmentation are necessary…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Haohang Xu , Shuangrui Ding , Manqi Zhao , Dongsheng Jiang

Molecular subtyping of PDAC into basal-like and classical has established prognostic and predictive value. However, its use in clinical practice is limited by cost, turnaround time, and tissue requirements, thereby restricting its…

Signet ring cells (SRCs), associated with a high propensity for peripheral metastasis and poor prognosis, critically influence surgical decision-making and outcome prediction. However, their detection remains challenging even for…

Image and Video Processing · Electrical Eng. & Systems 2025-07-23 Zhu Meng , Junhao Dong , Limei Guo , Fei Su , Jiaxuan Liu , Guangxi Wang , Zhicheng Zhao

Pathological anomalies exhibit diverse appearances in medical imaging, making it difficult to collect and annotate a representative amount of data required to train deep learning models in a supervised setting. Therefore, in this work, we…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mariana-Iuliana Georgescu

A brain tumour is a mass or cluster of abnormal cells in the brain, which has the possibility of becoming life-threatening because of its ability to invade neighbouring tissues and also form metastases. An accurate diagnosis is essential…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Soumick Chatterjee , Faraz Ahmed Nizamani , Andreas Nürnberger , Oliver Speck

Precise prognostic stratification of colorectal cancer (CRC) remains a major clinical challenge due to its high heterogeneity. The conventional TNM staging system is inadequate for personalized medicine. We aimed to develop and validate a…

Machine Learning · Computer Science 2025-11-20 Zisong Wang , Xuanyu Wang , Hang Chen , Haizhou Wang , Yuxin Chen , Yihang Xu , Yunhe Yuan , Lihuan Luo , Xitong Ling , Xiaoping Liu

Glioblastoma (GBM) is a highly aggressive primary brain tumor with limited therapeutic options and poor prognosis. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is a critical molecular biomarker…

Machine Learning · Computer Science 2026-01-13 Hasan M Jamil

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

The pancreatic disease taxonomy includes ten types of masses (tumors or cysts)[20,8]. Previous work focuses on developing segmentation or classification methods only for certain mass types. Differential diagnosis of all mass types is…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Tianyi Zhao , Kai Cao , Jiawen Yao , Isabella Nogues , Le Lu , Lingyun Huang , Jing Xiao , Zhaozheng Yin , Ling Zhang

Accurately predicting the survival rate of cancer patients is crucial for aiding clinicians in planning appropriate treatment, reducing cancer-related medical expenses, and significantly enhancing patients' quality of life. Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Liangrui Pan , Yijun Peng , Yan Li , Xiang Wang , Wenjuan Liu , Liwen Xu , Qingchun Liang , Shaoliang Peng

Brain tumor segmentation remains a significant challenge, particularly in the context of multi-modal magnetic resonance imaging (MRI) where missing modality images are common in clinical settings, leading to reduced segmentation accuracy.…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Zhongao Sun , Jiameng Li , Yuhan Wang , Jiarong Cheng , Qing Zhou , Chun Li

Skin cancer classification is a crucial task in medical image analysis, where precise differentiation between malignant and non-malignant lesions is essential for early diagnosis and treatment. In this study, we explore Sequential and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Shubhi Agarwal , Amulya Kumar Mahto

Esophageal cancer is among the most common types of cancer worldwide. It is traditionally treated using open esophagectomy, but in recent years, robot-assisted minimally invasive esophagectomy (RAMIE) has emerged as a promising alternative.…

Accurate detection of colorectal cancer and early prevention heavily rely on precise polyp identification during gastrointestinal colonoscopy. Due to limited data, many current state-of-the-art deep learning methods for polyp segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Ankush Gajanan Arudkar , Bernard J. E. Evans

Due to the high heterogeneity and clinical characteristics of cancer, there are significant differences in multi-omic data and clinical characteristics among different cancer subtypes. Therefore, accurate classification of cancer subtypes…

Quantitative Methods · Quantitative Biology 2023-08-23 Liangrui Pan , Dazheng Liu , Zhichao Feng , Wenjuan Liu , Shaoliang Peng

Accurate subtype classification and outcome prediction in mesothelioma are essential for guiding therapy and patient care. Most computational pathology models are trained on large tissue images from resection specimens, limiting their use…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Farzaneh Seyedshahi , Francesca Damiola , Sylvie Lantuejoul , Ke Yuan , John Le Quesne

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

In this paper, we studied extensively on different deep learning based methods to detect melanoma and skin lesion cancers. Melanoma, a form of malignant skin cancer is very threatening to health. Proper diagnosis of melanoma at an earlier…

Computer Vision and Pattern Recognition · Computer Science 2019-01-31 Md Ashraful Alam Milton

A Deep Autoencoder based content retrieval algorithm is proposed for prediction and differentiation of cancer types based on the presence of epigenetic patterns of DNA methylation identified in genetic regions known as CpG islands. The…

Quantitative Methods · Quantitative Biology 2018-10-08 Mohammed Khwaja , Melpomeni Kalofonou , Chris Toumazou