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For mental disorders, patients' underlying mental states are non-observed latent constructs which have to be inferred from observed multi-domain measurements such as diagnostic symptoms and patient functioning scores. Additionally,…

Machine Learning · Computer Science 2020-11-03 Yuan Chen , Donglin Zeng , Tianchen Xu , Yuanjia Wang

Despite the centrality of the notion of representation in neuroscience, the field lacks a unified framework for the concepts used to characterize representation, leading to disparate use of both terminology and measures associated with it.…

Neurons and Cognition · Quantitative Biology 2026-04-27 Stephan Pohl , Edgar Y. Walker , David L. Barack , Jennifer Lee , Rachel N. Denison , Ned Block , Florent Meyniel , Wei Ji Ma

Chronic pain is a pervasive disorder which is often very disabling and is associated with comorbidities such as depression and anxiety. Neuropathic Pain (NP) is a common sub-type which is often caused due to nerve damage and has a known…

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Individualized cognitive simulation (ICS) aims to build computational models that approximate the thought processes of specific individuals. While large language models (LLMs) convincingly mimic surface-level human behavior such as…

Artificial Intelligence · Computer Science 2025-10-24 Tianyi Zhang , Xiaolin Zhou , Yunzhe Wang , Erik Cambria , David Traum , Rui Mao

Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets…

Machine Learning · Statistics 2018-07-05 Laura Aviñó , Matteo Ruffini , Ricard Gavaldà

Semidefinite programs (SDPs) -- some of the most useful and versatile optimization problems of the last few decades -- are often pathological: the optimal values of the primal and dual problems may differ and may not be attained. Such SDPs…

Optimization and Control · Mathematics 2019-10-23 Gabor Pataki

Social media is one of the most highly sought resources for analyzing characteristics of the language by its users. In particular, many researchers utilized various linguistic features of mental health problems from social media. However,…

Computation and Language · Computer Science 2023-06-06 Hoyun Song , Jisu Shin , Huije Lee , Jong C. Park

Multiple Sclerosis (MS) is a chronic, inflammatory and degenerative neurological disease, which is monitored by a specialist using the Expanded Disability Status Scale (EDSS) and recorded in unstructured text in the form of a neurology…

Computation and Language · Computer Science 2020-10-30 Alister D Costa , Stefan Denkovski , Michal Malyska , Sae Young Moon , Brandon Rufino , Zhen Yang , Taylor Killian , Marzyeh Ghassemi

Background: Mathematical modeling approaches are becoming ever more established in clinical neuroscience. They provide insight that is key to understand complex interactions of network phenomena, in general, and interactions within the…

Neurons and Cognition · Quantitative Biology 2014-04-25 Markus A. Dahlem , Jürgen Kurths , Michel D. Ferrari , Kazuyuki Aihara , Marten Scheffer , Arne May

Image translation across domains for unpaired datasets has gained interest and great improvement lately. In medical imaging, there are multiple imaging modalities, with very different characteristics. Our goal is to use cross-modality…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Leo Segre , Or Hirschorn , Dvir Ginzburg , Dan Raviv

Objective. Standard Magnetic Resonance Imaging (MRI) reconstruction pipelines discard phase information captured during acquisition, despite evidence that it encodes tissue properties relevant to tumor diagnosis. Current machine learning…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Marco Schlimbach , Moritz Rempe , Jessica Mnischek , Lukas T. Rotkopf , Jens Weingarten , Jens Kleesiek , Kevin Kröninger

We introduce profile matching, a multivariate matching method for randomized experiments and observational studies that finds the largest possible unweighted samples across multiple treatment groups that are balanced relative to a covariate…

Methodology · Statistics 2022-07-07 Eric R. Cohn , Jose R. Zubizarreta

Rationalization is to employ a generator and a predictor to construct a self-explaining NLP model in which the generator selects a subset of human-intelligible pieces of the input text to the following predictor. However, rationalization…

Machine Learning · Computer Science 2023-07-25 Wei Liu , Haozhao Wang , Jun Wang , Ruixuan Li , Xinyang Li , Yuankai Zhang , Yang Qiu

Recent developed graph-based methods for diagnosing brain disorders using functional connectivity highly rely on predefined brain atlases, but overlook the rich information embedded within atlases and the confounding effects of site and…

Machine Learning · Computer Science 2025-10-16 Qianqian Liao , Wuque Cai , Hongze Sun , Dongze Liu , Duo Chen , Dezhong Yao , Daqing Guo

Improving the explainability of the results from machine learning methods has become an important research goal. Here, we study the problem of making clusters more interpretable by extending a recent approach of [Davidson et al., NeurIPS…

Data Structures and Algorithms · Computer Science 2020-02-10 Prathyush Sambaturu , Aparna Gupta , Ian Davidson , S. S. Ravi , Anil Vullikanti , Andrew Warren

Conversational diagnosis requires multi-turn history-taking, where an agent asks clarifying questions to refine differential diagnoses under incomplete information. Existing approaches often rely on the parametric knowledge of a model or…

Artificial Intelligence · Computer Science 2026-02-04 Jeongmoon Won , Seungwon Kook , Yohan Jo

Predicting the presence of major depressive disorder (MDD) using behavioural and cognitive signals is a highly non-trivial task. The heterogeneous clinical profile of MDD means that any given speech, facial expression and/or observed…

Machine Learning · Computer Science 2023-06-26 Salvatore Fara , Orlaith Hickey , Alexandra Georgescu , Stefano Goria , Emilia Molimpakis , Nicholas Cummins

Explanations shed light on a machine learning model's rationales and can aid in identifying deficiencies in its reasoning process. Explanation generation models are typically trained in a supervised way given human explanations. When such…

Machine Learning · Computer Science 2021-09-09 Pepa Atanasova , Jakob Grue Simonsen , Christina Lioma , Isabelle Augenstein

The modular composite representation (MCR) is a computing model that represents information with high-dimensional integer vectors using modular arithmetic. Originally proposed as a generalization of the binary spatter code model, it aims to…

Machine Learning · Computer Science 2025-11-14 Marco Angioli , Christopher J. Kymn , Antonello Rosato , Amy Loutfi , Mauro Olivieri , Denis Kleyko
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