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Adapting Large Language Models (LLMs) for agent tasks is critical in developing language agents. Direct Preference Optimization (DPO) is a promising technique for this adaptation with the alleviation of compounding errors, offering a means…

Computation and Language · Computer Science 2025-02-25 Wentao Shi , Mengqi Yuan , Junkang Wu , Qifan Wang , Fuli Feng

Large language models in the past have typically relied on some form of reinforcement learning with human feedback (RLHF) to better align model responses with human preferences. However, because of oft-observed instabilities when…

Computation and Language · Computer Science 2024-07-15 Xiangkun Hu , Tong He , David Wipf

The ability to train high-performing reward models with few-shot data is critical for enhancing the efficiency and scalability of Reinforcement Learning from Human Feedback (RLHF). We propose a data augmentation and expansion framework that…

Machine Learning · Computer Science 2025-06-11 Yiyang Zhao , Huiyu Bai , Xuejiao Zhao

Diffusion models have achieved promising results for Structure-Based Drug Design (SBDD). Nevertheless, high-quality protein subpocket and ligand data are relatively scarce, which hinders the models' generation capabilities. Recently, Direct…

Biomolecules · Quantitative Biology 2026-02-11 Xiwei Cheng , Xiangxin Zhou , Yuwei Yang , Yu Bao , Quanquan Gu

The rapid development of large language model (LLM) alignment algorithms has resulted in a complex and fragmented landscape, with limited clarity on the effectiveness of different methods and their inter-connections. This paper introduces…

DPO is an effective preference optimization algorithm. However, the DPO-tuned models tend to overfit on the dispreferred samples, manifested as overly long generations lacking diversity. While recent regularization approaches have…

Computation and Language · Computer Science 2025-08-26 Chenxu Yang , Ruipeng Jia , Naibin Gu , Zheng Lin , Siyuan Chen , Chao Pang , Weichong Yin , Yu Sun , Hua Wu , Weiping Wang

Recently, there has been significant interest in replacing the reward model in Reinforcement Learning with Human Feedback (RLHF) methods for Large Language Models (LLMs), such as Direct Preference Optimization (DPO) and its variants. These…

Computation and Language · Computer Science 2024-09-27 Jian Li , Haojing Huang , Yujia Zhang , Pengfei Xu , Xi Chen , Rui Song , Lida Shi , Jingwen Wang , Hao Xu

Large Vision-Language Models (LVLMs) hold significant promise for medical applications, yet their deployment is often constrained by insufficient alignment and reliability. While Direct Preference Optimization (DPO) has emerged as a potent…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Dain Kim , Jiwoo Lee , Jaehoon Yun , Yong Hoe Koo , Qingyu Chen , Hyunjae Kim , Jaewoo Kang

Direct Preference Optimization (DPO) is broadly utilized for aligning Large Language Models (LLMs) with human values because of its flexibility. Despite its effectiveness, it has been observed that the capability of DPO to generate…

Machine Learning · Computer Science 2025-05-20 Wenqiao Zhu , Ji Liu , Lulu Wang , Jun Wu , Yulun Zhang

Existing post-training techniques are broadly categorized into supervised fine-tuning (SFT) and reinforcement learning (RL) methods; the former is stable during training but suffers from limited generalization, while the latter, despite its…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Daoan Zhang , Guangchen Lan , Dong-Jun Han , Wenlin Yao , Xiaoman Pan , Hongming Zhang , Mingxiao Li , Pengcheng Chen , Yu Dong , Christopher Brinton , Jiebo Luo

Direct Preference Optimization (DPO) has been widely adopted for large language model alignment due to its simple training procedure and lack of an explicit reward model. However, in iterative DPO, when the policy model from the previous…

Information Retrieval · Computer Science 2026-05-25 Lingling Fu , Yongfu Xu

Fairness in Continual Learning for Large Multimodal Models (LMMs) is an emerging yet underexplored challenge, particularly in the presence of imbalanced data distributions that can lead to biased model updates and suboptimal performance…

Machine Learning · Computer Science 2026-03-31 Thanh-Dat Truong , Huu-Thien Tran , Jackson Cothren , Bhiksha Raj , Khoa Luu

Large language models (LLMs) have revolutionized the role of AI, yet pose potential social risks. To steer LLMs towards human preference, alignment technologies have been introduced and gained increasing attention. Nevertheless, existing…

Computation and Language · Computer Science 2024-10-01 Shitong Duan , Xiaoyuan Yi , Peng Zhang , Yan Liu , Zheng Liu , Tun Lu , Xing Xie , Ning Gu

Recent alignment methods based on Direct Preference Optimization (DPO) reformulate preference learning as supervised optimization over pairwise comparisons, offering improved efficiency and stability over reinforcement learning from human…

Machine Learning · Computer Science 2026-01-22 Yuhui Sun , Xiyao Wang , Zixi Li , YiTian Ding , Tianyang Ling , Jialuo Chen , Tianyi Yu , Zhenlong Yuan , Jinman Zhao

Direct Preference Optimization (DPO) has emerged as a lightweight and effective alternative to Reinforcement Learning from Human Feedback (RLHF) and Reinforcement Learning with AI Feedback (RLAIF) for aligning large language and…

Artificial Intelligence · Computer Science 2025-12-16 Zihui Zhao , Zechang Li

Aligning Large Language Models (LLMs) to human preferences in content, style, and presentation is challenging, in part because preferences are varied, context-dependent, and sometimes inherently ambiguous. While successful, Reinforcement…

Machine Learning · Computer Science 2024-10-29 Sam Houliston , Alizée Pace , Alexander Immer , Gunnar Rätsch

With the rapid development and widespread application of Large Language Models (LLMs), their potential safety risks have attracted widespread attention. Reinforcement Learning from Human Feedback (RLHF) has been adopted to enhance the…

Artificial Intelligence · Computer Science 2026-03-25 Shiji Zhao , Mengyang Wang , Shukun Xiong , Fangzhou Chen , Qihui Zhu , Shouwei Ruan , Yisong Xiao , Ranjie Duan , Xun Chen , XingXing Wei

Iterative self-improvement, a concept extending beyond personal growth, has found powerful applications in machine learning, particularly in transforming weak models into strong ones. While recent advances in natural language processing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Daechul Ahn , Yura Choi , San Kim , Youngjae Yu , Dongyeop Kang , Jonghyun Choi

Improving the alignment of language models with human preferences remains an active research challenge. Previous approaches have primarily utilized Reinforcement Learning from Human Feedback (RLHF) via online RL methods such as Proximal…

Computation and Language · Computer Science 2024-01-25 Tianqi Liu , Yao Zhao , Rishabh Joshi , Misha Khalman , Mohammad Saleh , Peter J. Liu , Jialu Liu

Aligning large language models (LLMs) with human values is an increasingly critical step in post-training. Direct Preference Optimization (DPO) has emerged as a simple, yet effective alternative to reinforcement learning from human feedback…

Artificial Intelligence · Computer Science 2025-07-29 Yifan Wang , Runjin Chen , Bolian Li , David Cho , Yihe Deng , Ruqi Zhang , Tianlong Chen , Zhangyang Wang , Ananth Grama , Junyuan Hong