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To analyze the impacts of certain types of public health interventions we need to estimate the treatment effects and outcomes as these apply to heterogeneous open populations. Dynamically modifying populations containing risk groups that…

Methodology · Statistics 2019-10-14 Aditi Shenvi , Jim Q. Smith

Knowledge graph integration typically suffers from the widely existing dangling entities that cannot find alignment cross knowledge graphs (KGs). The dangling entity set is unavailable in most real-world scenarios, and manually mining the…

Computation and Language · Computer Science 2022-03-11 Shengxuan Luo , Sheng Yu

The label scarcity problem is the main challenge that hinders the wide application of deep learning systems in automatic cardiovascular diseases (CVDs) detection using electrocardiography (ECG). Tuning pre-trained models alleviates this…

Machine Learning · Computer Science 2024-11-18 Rushuang Zhou , Lei Clifton , Zijun Liu , Kannie W. Y. Chan , David A. Clifton , Yuan-Ting Zhang , Yining Dong

Processes such as disease propagation and information diffusion often spread over some latent network structure which must be learned from observation. Given a set of unlabeled training examples representing occurrences of an event type of…

Machine Learning · Statistics 2017-01-09 Sriram Somanchi , Daniel B. Neill

Background: Electroencephalography (EEG) monitors brain activity during sleep and is used to identify sleep disorders. In sleep medicine, clinicians interpret raw EEG signals in so-called sleep stages, which are assigned by experts to every…

Signal Processing · Electrical Eng. & Systems 2018-12-12 Stanislas Chambon , Valentin Thorey , Pierrick J. Arnal , Emmanuel Mignot , Alexandre Gramfort

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Multimodal electronic health record (EHR) data is useful for disease risk prediction based on medical domain knowledge. However, general medical knowledge must be adapted to specific healthcare settings and patient populations to achieve…

Artificial Intelligence · Computer Science 2025-09-29 Mbithe Nzomo , Deshendran Moodley

Clinical language models (LMs) are increasingly applied to support clinical risk prediction from free-text notes, yet their uncertainty estimates often remain poorly calibrated and clinically unreliable. In this work, we propose Clinical…

Computation and Language · Computer Science 2026-04-27 Sizhe Wang , Ziqi Xu , Claire Najjuuko , Charles Alba , Chenyang Lu

Computational analysis on physiological signals would provide immense impact for enabling automated clinical analytics. However, the class imbalance issue where negative or minority class instances are rare in number impairs the robustness…

Medical Physics · Physics 2018-12-19 Arijit Ukil , Soma Bandyopadhyay , Chetanya Puri , Rituraj Singh , Arpan Pal

Designing a new clinical trial entails many decisions, such as defining a cohort and setting the study objectives to name a few, and therefore can benefit from recommendations based on exhaustive mining of past clinical trial records. Here,…

Artificial Intelligence · Computer Science 2023-09-29 Murthy V. Devarakonda , Smita Mohanty , Raja Rao Sunkishala , Nag Mallampalli , Xiong Liu

Here we study the semantic search and retrieval problem in biomedical digital libraries. First, we introduce MedGraph, a knowledge graph embedding-based method that provides semantic relevance retrieval and ranking for the biomedical…

Information Retrieval · Computer Science 2021-12-15 Islam Akef Ebeid , Elizabeth Pierce

Electrocardiogram (ECG) diagnosis remains challenging due to limited labeled data and the need to capture subtle yet clinically meaningful variations in rhythm and morphology. We present CREMA (Contrastive Regularized Masked Autoencoder), a…

Machine Learning · Computer Science 2025-08-22 Junho Song , Jong-Hwan Jang , DongGyun Hong , Joon-myoung Kwon , Yong-Yeon Jo

The increasing reliance on Computed Tomography Pulmonary Angiography (CTPA) for Pulmonary Embolism (PE) diagnosis presents challenges and a pressing need for improved diagnostic solutions. The primary objective of this study is to leverage…

Anomaly detection in images plays a significant role for many applications across all industries, such as disease diagnosis in healthcare or quality assurance in manufacturing. Manual inspection of images, when extended over a monotonously…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Vincent Wilmet , Sauraj Verma , Tabea Redl , Håkon Sandaker , Zhenning Li

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

In medical image segmentation, skip connections are used to merge global context and reduce the semantic gap between encoder and decoder. Current methods often struggle with limited structural representation and insufficient contextual…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Weixuan Li , Quanjun Li , Guang Yu , Song Yang , Zimeng Li , Chi-Man Pun , Yupeng Liu , Xuhang Chen

Risk mitigation techniques are critical to avoiding accidents associated with driving behaviour. We provide a novel Multi-Class Driver Distraction Risk Assessment (MDDRA) model that considers the vehicle, driver, and environmental data…

Machine Learning · Computer Science 2024-02-22 Adebamigbe Fasanmade , Ali H. Al-Bayatti , Jarrad Neil Morden , Fabio Caraffini

Epilepsy is a neurological disorder and for its detection, encephalography (EEG) is a commonly used clinical approach. Manual inspection of EEG brain signals is a time-consuming and laborious process, which puts heavy burden on neurologists…

Computer Vision and Pattern Recognition · Computer Science 2018-01-17 Ihsan Ullah , Muhammad Hussain , Emad-ul-Haq Qazi , Hatim Aboalsamh

Deep neural networks (DNNs) for medical images are extremely vulnerable to adversarial examples (AEs), which poses security concerns on clinical decision making. Luckily, medical AEs are also easy to detect in hierarchical feature space per…

Computer Vision and Pattern Recognition · Computer Science 2021-05-31 Qingsong Yao , Zecheng He , Yi Lin , Kai Ma , Yefeng Zheng , S. Kevin Zhou

Side effects of prescribed medications are a common occurrence. Electronic healthcare databases present the opportunity to identify new side effects efficiently but currently the methods are limited due to confounding (i.e. when an…

Databases · Computer Science 2016-11-17 Jenna M. Reps , Uwe Aickelin , Jiangang Ma , Yanchun Zhang