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Drug synergy prediction (DSP) aims to identify efficacious drug combinations under various cellular contexts with different targets. However, the continual emergence of novel compounds results in variations in molecular scaffolds and sizes,…

Machine Learning · Computer Science 2026-05-29 Xin Wang , Linxin Xiao , Yang Yao , Wenwu Zhu

With the unprecedented proliferation of machine learning software, there is an ever-increasing need to generate efficient code for such applications. State-of-the-art deep-learning compilers like TVM and Halide incorporate a learning-based…

Machine Learning · Computer Science 2021-08-31 Shikhar Singh , Benoit Steiner , James Hegarty , Hugh Leather

Deep learning (DL) is becoming the cornerstone of numerous applications both in datacenters and at the edge. Specialized hardware is often necessary to meet the performance requirements of state-of-the-art DL models, but the rapid pace of…

Hardware Architecture · Computer Science 2025-12-16 Andrew Boutros , Aman Arora , Vaughn Betz

Several methods exist today to accelerate Machine Learning(ML) or Deep-Learning(DL) model performance for training and inference. However, modern techniques that rely on various graph and operator parallelism methodologies rely on search…

Machine Learning · Computer Science 2023-08-23 Srinjoy Das , Lawrence Rauchwerger

As Deep Learning (DL) models have been increasingly used in latency-sensitive applications, there has been a growing interest in improving their response time. An important venue for such improvement is to profile the execution of these…

Machine Learning · Computer Science 2020-06-04 Cheng Li , Abdul Dakkak , Jinjun Xiong , Wen-mei Hwu

Recently [Bhattacharya et al., STOC 2015] provide the first non-trivial algorithm for the densest subgraph problem in the streaming model with additions and deletions to its edges, i.e., for dynamic graph streams. They present a…

Data Structures and Algorithms · Computer Science 2015-07-30 Hossein Esfandiari , MohammadTaghi Hajiaghayi , David P. Woodruff

Enabling effective and efficient machine learning (ML) over large-scale graph data (e.g., graphs with billions of edges) can have a great impact on both industrial and scientific applications. However, existing efforts to advance…

Machine Learning · Computer Science 2021-10-22 Weihua Hu , Matthias Fey , Hongyu Ren , Maho Nakata , Yuxiao Dong , Jure Leskovec

Deep Learning (DL) model-based AI services are increasingly offered in a variety of predictive analytics services such as computer vision, natural language processing, speech recognition. However, the quality of the DL models can degrade…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-04 Anirban Bhattacharjee , Ajay Dev Chhokra , Hongyang Sun , Shashank Shekhar , Aniruddha Gokhale , Gabor Karsai , Abhishek Dubey

A major contributor to the quality of a deep learning model is the selection of the optimizer. We propose a new dual-joint search space in the realm of neural optimizer search (NOS), along with an integrity check, to automate the process of…

Neural and Evolutionary Computing · Computer Science 2024-04-11 Brandon Morgan , Dean Hougen

Joint clustering and feature learning methods have shown remarkable performance in unsupervised representation learning. However, the training schedule alternating between feature clustering and network parameters update leads to unstable…

Computer Vision and Pattern Recognition · Computer Science 2020-06-19 Xiaohang Zhan , Jiahao Xie , Ziwei Liu , Yew Soon Ong , Chen Change Loy

This paper addresses the challenge of out-of-distribution (OOD) generalization in graph machine learning, a field rapidly advancing yet grappling with the discrepancy between source and target data distributions. Traditional graph learning…

Machine Learning · Computer Science 2024-08-09 Xin Sun , Liang Wang , Qiang Liu , Shu Wu , Zilei Wang , Liang Wang

Large-scale deep learning models contribute to significant performance improvements on varieties of downstream tasks. Current data and model parallelism approaches utilize model replication and partition techniques to support the…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-19 Youhe Jiang , Fangcheng Fu , Xupeng Miao , Xiaonan Nie , Bin Cui

Out-of-distribution (OOD) detection remains challenging for deep learning models, particularly when test-time OOD samples differ significantly from training outliers. We propose OODD, a novel test-time OOD detection method that dynamically…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Yifeng Yang , Lin Zhu , Zewen Sun , Hengyu Liu , Qinying Gu , Nanyang Ye

Fault-tolerant deep learning accelerator is the basis for highly reliable deep learning processing and critical to deploy deep learning in safety-critical applications such as avionics and robotics. Since deep learning is known to be…

Hardware Architecture · Computer Science 2023-12-22 Qing Zhang , Cheng Liu , Bo Liu , Haitong Huang , Ying Wang , Huawei Li , Xiaowei Li

Applying deep learning (DL) techniques in the electronic design automation (EDA) field has become a trending topic. Most solutions apply well-developed DL models to solve specific EDA problems. While demonstrating promising results, they…

Machine Learning · Computer Science 2022-04-22 Min Li , Sadaf Khan , Zhengyuan Shi , Naixing Wang , Yu Huang , Qiang Xu

The Deep Learning (DL) community sees many novel topologies published each year. Achieving high performance on each new topology remains challenging, as each requires some level of manual effort. This issue is compounded by the…

We present a deep reinforcement learning approach to minimizing the execution cost of neural network computation graphs in an optimizing compiler. Unlike earlier learning-based works that require training the optimizer on the same graph to…

Machine Learning · Computer Science 2020-02-11 Aditya Paliwal , Felix Gimeno , Vinod Nair , Yujia Li , Miles Lubin , Pushmeet Kohli , Oriol Vinyals

Most design methods contain a forward framework, asking for primary specifications of a building to generate an output or assess its performance. However, architects urge for specific objectives though uncertain of the proper design…

Computer Vision and Pattern Recognition · Computer Science 2021-06-10 Zohreh Shaghaghian , Wei Yan

Recent progress in deep learning has led to the development of Optical Character Recognition (OCR) systems which perform remarkably well. Most research has been around recurrent networks as well as complex gated layers which make the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-01 Kartik Chaudhary , Raghav Bali

The increasing inclusion of Deep Learning (DL) models in safety-critical systems such as autonomous vehicles have led to the development of multiple model-based DL testing techniques. One common denominator of these testing techniques is…

Machine Learning · Computer Science 2019-09-09 Houssem Ben Braiek , Foutse khomh