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Developing knowledge-driven contemporaneous health index (CHI) that can precisely reflect the underlying patient across the course of the condition's progression holds a unique value, like facilitating a range of clinical decision-making…

Methodology · Statistics 2019-02-25 Aven Samareh , Shuai Huang

In this study, we developed an Evidence-based Ensemble Neural Network, namely EVENet, for anatomical brain parcellation using diffusion MRI. The key innovation of EVENet is the design of an evidential deep learning framework to quantify…

learning algorithms. In this paper, we review the classification algorithms used in the health care system (chronic diseases) and present the neural network-based Ensemble learning method. We briefly describe the commonly used algorithms…

Machine Learning · Computer Science 2021-03-16 Jafar Abdollahi , Babak Nouri-Moghaddam , Mehdi Ghazanfari

Uncertainty quantification (UQ) has become critical for evaluating the reliability of artificial intelligence systems, especially in medical image segmentation. This study addresses the interpretability of instance-wise uncertainty values…

The feasibility of variational quantum algorithms, the most popular correspondent of neural networks on noisy, near-term quantum hardware, is highly impacted by the circuit depth of the involved parametrized quantum circuits (PQCs). Higher…

Machine Learning · Computer Science 2024-11-01 Philipp Schleich , Marta Skreta , Lasse B. Kristensen , Rodrigo A. Vargas-Hernández , Alán Aspuru-Guzik

Prediction uncertainty estimation has clinical significance as it can potentially quantify prediction reliability. Clinicians may trust 'blackbox' models more if robust reliability information is available, which may lead to more models…

Machine Learning · Computer Science 2022-10-04 Michael Dohopolski , Kai Wang , Biling Wang , Ti Bai , Dan Nguyen , David Sher , Steve Jiang , Jing Wang

Uncertainty Quantification (UQ) is crucial for ensuring the reliability of machine learning models deployed in real-world autonomous systems. However, existing approaches typically quantify task-level output prediction uncertainty without…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Luke Chen , Junyao Wang , Trier Mortlock , Pramod Khargonekar , Mohammad Abdullah Al Faruque

In principle, deep learning models trained on medical time-series, including wearable photoplethysmography (PPG) sensor data, can provide a means to continuously monitor physiological parameters outside of clinical settings. However, there…

Artificial intelligence techniques have achieved strong performance in classifying Windows Portable Executable (PE) malware, but their reliability often degrades under dataset shifts, leading to misclassifications with severe security…

Cryptography and Security · Computer Science 2025-12-23 Rahul Yumlembam , Biju Issac , Seibu Mary Jacob

As large language models are increasingly deployed for clinical text, ensuring they can reliably signal their own uncertainty becomes critical. Most existing uncertainty quantification (UQ) methods are designed for open-domain generation…

Computation and Language · Computer Science 2026-05-28 Bushi Xiao , Sarvesh Soni , Daisy Zhe Wang

Chest X-rays is one of the most commonly available and affordable radiological examinations in clinical practice. While detecting thoracic diseases on chest X-rays is still a challenging task for machine intelligence, due to 1) the highly…

Computer Vision and Pattern Recognition · Computer Science 2018-07-18 Chaochao Yan , Jiawen Yao , Ruoyu Li , Zheng Xu , Junzhou Huang

Chest X-ray is one of the most accessible medical imaging technique for diagnosis of multiple diseases. With the availability of ChestX-ray14, which is a massive dataset of chest X-ray images and provides annotations for 14 thoracic…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Pulkit Kumar , Monika Grewal , Muktabh Mayank Srivastava

Computer-aided techniques may lead to more accurate and more acces-sible diagnosis of thorax diseases on chest radiography. Despite the success of deep learning-based solutions, this task remains a major challenge in smart healthcare, since…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Hongyu Wang , Yong Xia

Reliable uncertainty quantification (UQ) is essential for deploying large language models (LLMs) in safety-critical scenarios, as it enables them to abstain from responding when uncertain, thereby avoiding hallucinations, i.e., plausible…

Computation and Language · Computer Science 2026-02-09 Xingtao Zhao , Hao Peng , Dingli Su , Xianghua Zeng , Chunyang Liu , Jinzhi Liao , Philip S. Yu

Deep neural networks (DNNs) have achieved tremendous success in computer vision, natural language processing, and scientific and engineering domains. However, DNNs can make unexpected, incorrect, yet overconfident predictions, leading to…

Machine Learning · Computer Science 2025-12-16 Wenchong He , Zhe Jiang , Tingsong Xiao , Zelin Xu , Yukun Li

The precision of contouring target structures and organs-at-risk (OAR) in radiotherapy planning is crucial for ensuring treatment efficacy and patient safety. Recent advancements in deep learning (DL) have significantly improved OAR…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Marvin Tom Teichmann , Manasi Datar , Lisa Kratzke , Fernando Vega , Florin C. Ghesu

Automated segmentation of tuberculosis (TB)-consistent lesions in chest X-rays (CXRs) using deep learning (DL) methods can help reduce radiologist effort, supplement clinical decision-making, and potentially result in improved patient…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Sivaramakrishnan Rajaraman , Feng Yang , Ghada Zamzmi , Peng Guo , Zhiyun Xue , Sameer K Antani

Uncertainty quantification (UQ) is an important component of molecular property prediction, particularly for drug discovery applications where model predictions direct experimental design and where unanticipated imprecision wastes valuable…

Machine Learning · Computer Science 2020-05-21 Lior Hirschfeld , Kyle Swanson , Kevin Yang , Regina Barzilay , Connor W. Coley

Learning on small data is a challenge frequently encountered in many real-world applications. In this work we study how effective quantum ensemble models are when trained on small data problems in healthcare and life sciences. We…

On noisy intermediate-scale quantum (NISQ) devices, expectation values of many observables are obtained through sampling-based approximations to trace-like quantities. A central limitation of this approach is destructive cancellation under…

Quantum Physics · Physics 2026-05-06 Myeongsu Kim , Manas Sajjan , Sabre Kais