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Recent advances in large generative models have shown that simple autoregressive formulations, when scaled appropriately, can exhibit strong zero-shot generalization across domains. Motivated by this trend, we investigate whether…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Yuxiang Lai , Jike Zhong , Ming Li , Yuheng Li , Xiaofeng Yang

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can…

Transfer learning represents a recent paradigm shift in the way we build artificial intelligence (AI) systems. In contrast to training task-specific models, transfer learning involves pre-training deep learning models on a large corpus of…

Glaucomatous optic neuropathy (GON) is a prevalent ocular disease that can lead to irreversible vision loss if not detected early and treated. The traditional diagnostic approach for GON involves a set of ophthalmic examinations, which are…

Deep learning and large public datasets have recently catalyzed the proliferation of AI models for processing brain recordings. However, systematically evaluating these models remains a challenge: not only do the preprocessing pipelines,…

Vision foundation models have demonstrated exceptional generalization capabilities in segmentation tasks for both generic and specialized images. However, a performance gap persists between foundation models and task-specific, specialized…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Chengxi Zeng , David Smithard , Alberto M Gambaruto , Tilo Burghardt

Pre-trained Foundation Models (PFMs) have ushered in a paradigm-shift in Artificial Intelligence, due to their ability to learn general-purpose representations that can be readily employed in a wide range of downstream tasks. While PFMs…

Databases · Computer Science 2024-11-13 Pasquale Balsebre , Weiming Huang , Gao Cong , Yi Li

Robotic Foundation Models (RFMs) hold great promise as generalist, end-to-end systems for robot control. Yet their ability to generalize across new environments, tasks, and embodiments remains limited. We argue that a major bottleneck lies…

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

The upsurge in pre-trained large models started by ChatGPT has swept across the entire deep learning community. Such powerful models demonstrate advanced generative ability and multimodal understanding capability, which quickly set new…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Ning Ding , Yehui Tang , Zhongqian Fu , Chao Xu , Kai Han , Yunhe Wang

Neuropathic pain, affecting up to 10% of adults, remains difficult to treat due to limited therapeutic efficacy and tolerability. Although resting-state functional MRI (rs-fMRI) is a promising non-invasive measurement of brain biomarkers to…

Machine Learning · Computer Science 2025-03-04 Wenrui Fan , L. M. Riza Rizky , Jiayang Zhang , Chen Chen , Haiping Lu , Kevin Teh , Dinesh Selvarajah , Shuo Zhou

Medical image analysis and computer-assisted intervention problems are increasingly being addressed with deep-learning-based solutions. Established deep-learning platforms are flexible but do not provide specific functionality for medical…

Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Dingyu Wang , Zimu Yuan , Jiajun Liu , Shanggui Liu , Nan Zhou , Tianxing Xu , Di Huang , Dong Jiang

Artificial intelligence (AI) has demonstrated considerable potential in the realm of medical imaging. However, the development of high-performance AI models typically necessitates training on large-scale, centralized datasets. This approach…

Cryptography and Security · Computer Science 2025-08-29 Mengyu Sun , Ziyuan Yang , Yongqiang Huang , Hui Yu , Yingyu Chen , Shuren Qi , Andrew Beng Jin Teoh , Yi Zhang

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

While brain-inspired artificial intelligence(AI) has demonstrated promising results, current understanding of the parallels between artificial neural networks (ANNs) and human brain processing remains limited: (1) unimodal ANN studies fail…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Yudan Ren , Xinlong Wang , Kexin Wang , Tian Xia , Zihan Ma , Zhaowei Li , Xiangrong Bi , Xiao Li , Xiaowei He

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Deep learning has revolutionized neuroimage analysis by delivering unprecedented speed and accuracy. However, the narrow scope of many training datasets constrains model robustness and generalizability. This challenge is particularly acute…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Malte Hoffmann

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To…

Machine Learning · Computer Science 2024-09-18 Jiaqi Ding , Tingting Dan , Ziquan Wei , Hyuna Cho , Paul J. Laurienti , Won Hwa Kim , Guorong Wu
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