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Generative large language models (LLMs) have shown great success in various applications, including question-answering (QA) and dialogue systems. However, in specialized domains like traditional Chinese medical QA, these models may perform…

Computation and Language · Computer Science 2023-09-06 Yang Tan , Mingchen Li , Zijie Huang , Huiqun Yu , Guisheng Fan

Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay…

Computation and Language · Computer Science 2023-04-12 Ruixiang Tang , Xiaotian Han , Xiaoqian Jiang , Xia Hu

This paper explores enhancing empathy in Large Language Models (LLMs) by integrating them with physiological data. We propose a physiological computing approach that includes developing deep learning models that use physiological data for…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Poorvesh Dongre , Majid Behravan , Kunal Gupta , Mark Billinghurst , Denis Gračanin

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Long-horizon interactions between users and LLM-based assistants necessitate effective memory management, yet current approaches face challenges in training and evaluation of memory. Existing memory benchmarks rely on static, off-policy…

Computation and Language · Computer Science 2026-03-03 Cheng Jiayang , Dongyu Ru , Lin Qiu , Yiyang Li , Xuezhi Cao , Yangqiu Song , Xunliang Cai

Personalized digital health support requires long-horizon, cross-dimensional reasoning over heterogeneous lifestyle signals, and recent advances in mobile sensing and large language models (LLMs) make such support increasingly feasible.…

Artificial Intelligence · Computer Science 2026-01-21 Ye Tian , Zihao Wang , Onat Gungor , Xiaoran Fan , Tajana Rosing

Large language models (LLMs) have been a disruptive innovation in recent years, and they play a crucial role in our daily lives due to their ability to understand and generate human-like text. Their capabilities include natural language…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-17 Akrit Mudvari , Yuang Jiang , Leandros Tassiulas

Current-generation Large Language Models (LLMs) have stirred enormous interest in recent months, yielding great potential for accessibility and automation, while simultaneously posing significant challenges and risk of misuse. To facilitate…

Access to humanities research databases is often hindered by the limitations of traditional interaction formats, particularly in the methods of searching and response generation. This study introduces an LLM-based smart assistant designed…

Computation and Language · Computer Science 2025-06-03 Alexander Sergeev , Valeriya Goloviznina , Mikhail Melnichenko , Evgeny Kotelnikov

The discovery of novel small molecule drugs remains a critical scientific challenge with far-reaching implications for treating diseases and advancing human health. Traditional drug development--especially for small molecule…

Biomolecules · Quantitative Biology 2025-04-01 Bowen Gao , Yanwen Huang , Yiqiao Liu , Wenxuan Xie , Wei-Ying Ma , Ya-Qin Zhang , Yanyan Lan

Proactive agents that anticipate user intentions without explicit prompts represent a significant evolution in human-AI interaction, promising to reduce cognitive load and streamline workflows. However, existing datasets suffer from two…

Human-Computer Interaction · Computer Science 2026-02-11 Yuanbo Tang , Huaze Tang , Tingyu Cao , Lam Nguyen , Anping Zhang , Xinwen Cao , Chunkang Liu , Wenbo Ding , Yang Li

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Natural Language Processing (NLP) and Voice Recognition agents are rapidly evolving healthcare by enabling efficient, accessible, and professional patient support while automating grunt work. This report serves as my self project wherein…

Audio and Speech Processing · Electrical Eng. & Systems 2025-02-21 Kabir Kumar

Drug discovery remains a formidable challenge: more than 90 percent of candidate molecules fail in clinical evaluation, and development costs often exceed one billion dollars per approved therapy. Disparate data streams, from genomics and…

Artificial Intelligence · Computer Science 2025-04-28 Kevin Song , Andrew Trotter , Jake Y. Chen

Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving…

Computation and Language · Computer Science 2025-06-10 Zhuoyun Du , Lujie Zheng , Renjun Hu , Yuyang Xu , Xiawei Li , Ying Sun , Wei Chen , Jian Wu , Haolei Cai , Haohao Ying

Recent advances in Retrieval-Augmented Generation (RAG) have enabled large language models (LLMs) to ground outputs in clinical evidence. However, connecting LLMs with external databases introduces the risk of contextual leakage: a subtle…

Computation and Language · Computer Science 2026-03-17 Shaowei Guan , Yu Zhai , Hin Chi Kwok , Jiawei Du , Xinyu Feng , Jing Li , Harry Qin , Vivian Hui

Medical consultations are intrinsically speech-centric. However, most prior works focus on long-text-based interactions, which are cumbersome and patient-unfriendly. Recent advances in speech language models (SpeechLMs) have enabled more…

Computation and Language · Computer Science 2026-04-21 Sirry Chen , Jieyi Wang , Wei Chen , Zhongyu Wei

We demonstrate an embodied conversational agent that can function as a receptionist and generate a mixture of open and closed-domain dialogue along with facial expressions, by using a large language model (LLM) to develop an engaging…