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With the rapid advances in high-throughput sequencing technologies, the focus of survival analysis has shifted from examining clinical indicators to incorporating genomic profiles with pathological images. However, existing methods either…

Image and Video Processing · Electrical Eng. & Systems 2023-09-25 Fengtao Zhou , Hao Chen

Survival prediction is a complicated ordinal regression task that aims to predict the ranking risk of death, which generally benefits from the integration of histology and genomic data. Despite the progress in joint learning from pathology…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Yingxue Xu , Hao Chen

Test-time adaptation (TTA) enables online model adaptation using only unlabeled test data, aiming to bridge the gap between source and target distributions. However, in multimodal scenarios, varying degrees of distribution shift across…

Machine Learning · Computer Science 2026-03-24 Jiacheng Li , Songhe Feng

Multimodal learning, which integrates data from diverse sensory modes, plays a pivotal role in artificial intelligence. However, existing multimodal learning methods often struggle with challenges where some modalities appear more dominant…

Machine Learning · Computer Science 2024-04-02 Xiaohui Zhang , Jaehong Yoon , Mohit Bansal , Huaxiu Yao

Test-Time Adaptation (TTA) has emerged as a promising paradigm for enhancing the generalizability of models. However, existing mainstream TTA methods, predominantly operating at batch level, often exhibit suboptimal performance in complex…

Machine Learning · Computer Science 2024-10-15 Yige Yuan , Bingbing Xu , Teng Xiao , Liang Hou , Fei Sun , Huawei Shen , Xueqi Cheng

Accurate survival prediction from multimodal medical data is essential for precision oncology, yet clinical deployment faces a persistent challenge: modalities are frequently incomplete due to cost constraints, technical limitations, or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Kyungwon Kim , Dosik Hwang

The integration of pathologic images and genomic data for survival analysis has gained increasing attention with advances in multimodal learning. However, current methods often ignore biological characteristics, such as heterogeneity and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Shuaiyu Zhang , Xun Lin , Rongxiang Zhang , Yu Bai , Yong Xu , Tao Tan , Xunbin Zheng , Zitong Yu

While multi-modal learning has advanced significantly, current approaches often treat modalities separately, creating inconsistencies in representation and reasoning. We introduce MANTA (Multi-modal Abstraction and Normalization via Textual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Ziqi Zhong , Daniel Tang

Multimodal Sentiment Analysis integrates Linguistic, Visual, and Acoustic. Mainstream approaches based on modality-invariant and modality-specific factorization or on complex fusion still rely on spatiotemporal mixed modeling. This ignores…

Computation and Language · Computer Science 2026-01-21 Chunlei Meng , Ziyang Zhou , Lucas He , Xiaojing Du , Chun Ouyang , Zhongxue Gan

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva

Multi-modal learning has shown exceptional performance in various tasks, especially in medical applications, where it integrates diverse medical information for comprehensive diagnostic evidence. However, there still are several challenges…

Machine Learning · Computer Science 2024-11-19 Lin Fan , Yafei Ou , Cenyang Zheng , Pengyu Dai , Tamotsu Kamishima , Masayuki Ikebe , Kenji Suzuki , Xun Gong

Cancer survival prediction requires integrating pathological Whole Slide Images (WSIs) and genomic profiles, a challenging task due to the inherent heterogeneity and the complexity of modeling both inter- and intra-modality interactions.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Mingxin Liu , Chengfei Cai , Jun Li , Pengbo Xu , Jinze Li , Jiquan Ma , Jun Xu

Multimodal pathology-genomic analysis has become increasingly prominent in cancer survival prediction. However, existing studies mainly utilize multi-instance learning to aggregate patch-level features, neglecting the information loss of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Mingcheng Qu , Guang Yang , Donglin Di , Tonghua Su , Yue Gao , Yang Song , Lei Fan

Cross-modal alignment is crucial for multimodal representation fusion due to the inherent heterogeneity between modalities. While Transformer-based methods have shown promising results in modeling inter-modal relationships, their quadratic…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Yan Li , Yifei Xing , Xiangyuan Lan , Xin Li , Haifeng Chen , Dongmei Jiang

Survival prediction, utilizing pathological images and genomic profiles, is increasingly important in cancer analysis and prognosis. Despite significant progress, precise survival analysis still faces two main challenges: (1) The massive…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Songhan Jiang , Zhengyu Gan , Linghan Cai , Yifeng Wang , Yongbing Zhang

Multi-modal learning has emerged as a crucial research direction, as integrating textual and visual information can substantially enhance performance in tasks such as classification, retrieval, and scene understanding. Despite advances with…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Md. Mithun Hossain , Md. Shakil Hossain , Sudipto Chaki , M. F. Mridha

Personalized Large Language Models (PLLMs) aim to align model outputs with individual user preferences, a crucial capability for user-centric applications. However, the prevalent approach of fine-tuning a separate module for each user faces…

Computation and Language · Computer Science 2025-11-27 Xiaopeng Li , Yuanjin Zheng , Wanyu Wang , wenlin zhang , Pengyue Jia , Yiqi Wang , Maolin Wang , Xuetao Wei , Xiangyu Zhao

Continual Test-Time Adaptation (CTTA) aims to empower perception systems to handle dynamic distribution shifts encountered after deployment. Existing methods predominantly follow a backward-alignment paradigm, which rigidly aligns incoming…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zhilin Zhu , Yabin Wang , Zhiheng Ma , Yaguang Song , Yaowei Wang , Xiaopeng Hong

Survival analysis using whole-slide images (WSIs) is crucial in cancer research. Despite significant successes, pathology images typically only provide slide-level labels, which hinders the learning of discriminative representations from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Chengsheng Zhang , Linhao Qu , Xiaoyu Liu , Zhijian Song

Vision Language Models (VLMs) have become essential backbones for multimodal intelligence, yet significant safety challenges limit their real-world application. While textual inputs are often effectively safeguarded, adversarial visual…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Yi Ding , Bolian Li , Ruqi Zhang
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