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The dynamic of complex ordering systems with active rotational degrees of freedom exemplified by protein self-assembly is explored using a machine learning workflow that combines deep learning-based semantic segmentation and rotationally…

Soft Condensed Matter · Physics 2021-04-26 Sergei V. Kalinin , Shuai Zhang , Mani Valleti , Harley Pyles , David Baker , James J. De Yoreo , Maxim Ziatdinov

Simulation and modeling are essential in product development, integrated into the design and manufacturing process to enhance efficiency and quality. They are typically represented as complex nonlinear differential algebraic equations. The…

Machine Learning · Computer Science 2026-03-25 Wenqiang Yang , Wenyuan Wu , Yong Feng , Changbo Chen

Geometric graph neural networks (GNNs) that respect E(3) symmetries have achieved strong performance on small molecule modeling, but they face scalability and expressiveness challenges when applied to large biomolecules such as RNA and…

Biomolecules · Quantitative Biology 2025-06-26 Junjie Xu , Jiahao Zhang , Mangal Prakash , Xiang Zhang , Suhang Wang

Recent years have seen rapid progress at the intersection between causality and machine learning. Motivated by scientific applications involving high-dimensional data, in particular in biomedicine, we propose a deep neural architecture for…

Machine Learning · Computer Science 2022-12-12 Kai Lagemann , Christian Lagemann , Bernd Taschler , Sach Mukherjee

The world is moving towards clean and renewable energy sources, such as wind energy, in an attempt to reduce greenhouse gas emissions that contribute to global warming. To enhance the analysis and storage of wind data, we introduce a deep…

Machine Learning · Computer Science 2024-11-07 Alif Bin Abdul Qayyum , Xihaier Luo , Nathan M. Urban , Xiaoning Qian , Byung-Jun Yoon

Real-time simulation of elastic structures is essential in many applications, from computer-guided surgical interventions to interactive design in mechanical engineering. The Finite Element Method is often used as the numerical method of…

Machine Learning · Computer Science 2021-09-21 Alban Odot , Ryadh Haferssas , Stéphane Cotin

Prior work has shown that the order in which different components of the face are learned using a sequential learner can play an important role in the performance of facial expression recognition systems. We propose FaceTopoNet, an…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Mojtaba Kolahdouzi , Alireza Sepas-Moghaddam , Ali Etemad

Recent advances in protein function prediction exploit graph-based deep learning approaches to correlate the structural and topological features of proteins with their molecular functions. However, proteins in vivo are not static but…

Biomolecules · Quantitative Biology 2022-11-22 Yuan Chiang , Wei-Han Hui , Shu-Wei Chang

Constitutive modeling based on continuum mechanics theory has been a classical approach for modeling the mechanical responses of materials. However, when constitutive laws are unknown or when defects and/or high degrees of heterogeneity are…

Machine Learning · Computer Science 2022-07-27 Huaiqian You , Quinn Zhang , Colton J. Ross , Chung-Hao Lee , Yue Yu

Representation of data on mixed variables, numerical and categorical types to get suitable feature map is a challenging task as important information lies in a complex non-linear manifold. The feature transformation should be able to…

Machine Learning · Computer Science 2020-09-22 Saswata Sahoo , Souradip Chakraborty

To develop a deep-learning method for achieving fast high-resolution MR elastography from highly undersampled data without the need of high-quality training dataset. We first framed the deep neural network representation as a nonlinear…

Signal Processing · Electrical Eng. & Systems 2026-01-21 Xi Peng

Effectively predicting transonic unsteady flow over an aerofoil poses inherent challenges. In this study, we harness the power of deep neural network (DNN) models using the attention U-Net architecture. Through efficient training of these…

Fluid Dynamics · Physics 2024-03-27 Li-Wei Chen , Nils Thuerey

It is widely believed that learning good representations is one of the main reasons for the success of deep neural networks. Although highly intuitive, there is a lack of theory and systematic approach quantitatively characterizing what…

Machine Learning · Computer Science 2018-11-30 Liwei Wang , Lunjia Hu , Jiayuan Gu , Yue Wu , Zhiqiang Hu , Kun He , John Hopcroft

Unsupervised image registration commonly adopts U-Net style networks to predict dense displacement fields in the full-resolution spatial domain. For high-resolution volumetric image data, this process is however resource-intensive and…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Xi Jia , Joseph Bartlett , Wei Chen , Siyang Song , Tianyang Zhang , Xinxing Cheng , Wenqi Lu , Zhaowen Qiu , Jinming Duan

Simulations are vital for understanding and predicting the evolution of complex molecular systems. However, despite advances in algorithms and special purpose hardware, accessing the timescales necessary to capture the structural evolution…

Computational Physics · Physics 2021-02-18 Pantelis R. Vlachas , Julija Zavadlav , Matej Praprotnik , Petros Koumoutsakos

Coarse-graining is a powerful tool for extending the reach of dynamic models of proteins and other biological macromolecules. Topological coarse-graining, in which biomolecules or sets thereof are represented via graph structures, is a…

Biomolecules · Quantitative Biology 2021-09-15 Vy Duong , Elizabeth Diessner , Gianmarc Grazioli , Rachel W. Martin , Carter T. Butts

Image Representation learning via input reconstruction is a common technique in machine learning for generating representations that can be effectively utilized by arbitrary downstream tasks. A well-established approach is using…

Neural and Evolutionary Computing · Computer Science 2025-06-10 Raoof HojatJalali , Edmondo Trentin

Deep learning, as a highly efficient method for metasurface inverse design, commonly use simulation data to train deep neural networks (DNNs) that can map desired functionalities to proper metasurface designs. However, the assumptions and…

Signal Processing · Electrical Eng. & Systems 2023-08-07 Jingxin Zhang , Jiawei Xi , Peixing Li , Ray C. C. Cheung , Alex M. H. Wong , Jensen Li

The predominant success of diffusion models in generative modeling has spurred significant interest in understanding their theoretical foundations. In this work, we propose a feature learning framework aimed at analyzing and comparing the…

Machine Learning · Statistics 2025-03-04 Andi Han , Wei Huang , Yuan Cao , Difan Zou

Artificial and biological agents cannon learn given completely random and unstructured data. The structure of data is encoded in the metric relationships between data points. In the context of neural networks, neuronal activity within a…

Machine Learning · Computer Science 2022-11-03 Kosio Beshkov , Jonas Verhellen , Mikkel Elle Lepperød
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