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Digitized adiabatic quantum factorization is a hybrid algorithm that exploits the advantage of digitized quantum computers to implement efficient adiabatic algorithms for factorization through gate decompositions of analog evolutions. In…

Quantum Physics · Physics 2026-02-05 Felip Pellicer , Juan José García-Ripoll , Alan C. Santos

In machine learning, fewer features reduce model complexity. Carefully assessing the influence of each input feature on the model quality is therefore a crucial preprocessing step. We propose a novel feature selection algorithm based on a…

Quantum Physics · Physics 2023-02-22 Sascha Mücke , Raoul Heese , Sabine Müller , Moritz Wolter , Nico Piatkowski

Current quantum programming is dominated by low-level, circuit-centric approaches that limit the potential for compiler optimization. This work presents how a high-level programming construct provides compilers with the semantic information…

Quantum Physics · Physics 2025-10-29 Evandro C. R. Rosa , Jerusa Marchi , Eduardo I. Duzzioni , Rafael de Santiago

Quantum optimization solvers typically rely on one-variable-to-one-qubit mapping. However, the low qubit count on current quantum computers is a major obstacle in competing against classical methods. Here, we develop a qubit-efficient…

Quantum Physics · Physics 2026-03-24 Bhuvanesh Sundar , Maxime Dupont

Quantum computers promise to perform certain computations exponentially faster than any classical device. Precise control over their physical implementation and proper shielding from unwanted interactions with the environment become more…

Quantum Physics · Physics 2021-11-19 Thomas Häner , Torsten Hoefler , Matthias Troyer

Algorithms and hardware for solving quadratic unconstrained binary optimization (QUBO) problems have made significant recent progress. This advancement has focused attention on formulating combinatorial optimization problems as quadratic…

Machine Learning · Computer Science 2025-08-26 Yuta Shikuri

Gaussian Processes are used in many applications to model spatial phenomena. Within this context, a key issue is to decide the set of locations where to take measurements so as to obtain a better approximation of the underlying function.…

Emerging Technologies · Computer Science 2019-01-31 Lorenzo Bottarelli , Alessandro Farinelli

Recent hardware demonstrations and advances in circuit compilation have made quantum computing with higher-dimensional systems (qudits) on near-term devices an attractive possibility. Some problems have more natural or optimal encodings…

Quantum Physics · Physics 2023-08-17 Gabriel Bottrill , Mudit Pandey , Olivia Di Matteo

Solving combinatorial optimization problems on near-term quantum devices has gained a lot of attraction in recent years. Currently, most works have focused on single-objective problems, whereas many real-world applications need to consider…

Quantum Physics · Physics 2025-06-06 Linus Ekstrom , Hao Wang , Sebastian Schmitt

In recent years, there is a growing interest in using quantum computers for solving combinatorial optimization problems. In this work, we developed a generic, machine learning-based framework for mapping continuous-space inverse design…

Quantum computing is developing fast. Real world applications are within reach in the coming years. One of the most promising areas is combinatorial optimisation, where the Quadratic Unconstrained Binary Optimisation (QUBO) problem…

Quantum Physics · Physics 2020-07-06 Frank Phillipson , Irina Chiscop

In recent years, the quantum computing community has seen an explosion of novel methods to implement non-trivial quantum computations on near-term hardware. An important direction of research has been to decompose an arbitrary entangled…

Quantum Physics · Physics 2021-11-24 Harsha Nagarajan , Owen Lockwood , Carleton Coffrin

Quadratic Unconstrained Binary Optimization (QUBO) provides a versatile framework for representing NP-hard combinatorial problems, yet existing solvers often face trade-offs among speed, accuracy, and scalability. In this work, we introduce…

Quantum Physics · Physics 2025-06-06 Jiecheng Yang , Ding Wang , Xiang Zhao , Hairui Zhang , Ming Gao , Lin Yang

Black-box optimization (BBO) can be used to optimize functions whose analytic form is unknown. A common approach to realising BBO is to learn a surrogate model which approximates the target black-box function which can then be solved via…

Machine Learning · Computer Science 2023-02-10 Jonas Nüßlein , Christoph Roch , Thomas Gabor , Jonas Stein , Claudia Linnhoff-Popien , Sebastian Feld

The Quadratic Unconstrained Binary Optimization (QUBO) model has gained prominence in recent years with the discovery that it unifies a rich variety of combinatorial optimization problems. By its association with the Ising problem in…

Data Structures and Algorithms · Computer Science 2019-11-06 Fred Glover , Gary Kochenberger , Yu Du

Here, we present two complementary approaches that advance quadratic unconstrained binary optimization (QUBO) toward practical use in data-driven materials design and other real-valued black-box optimization tasks. First, we introduce a…

Materials Science · Physics 2025-12-15 Thomas Plehn , Daniel Barragan-Yani , Eric Breitbarth , Guillermo Requena , David Melching

Quadratic unconstrained binary optimization (QUBO) provides problem formulations for various computational problems that can be solved with dedicated QUBO solvers, which can be based on classical or quantum computation. A common approach to…

Computed tomography (CT) is an important imaging technique used in medical analysis of the internal structure of the human body. Previously, image segmentation methods were required after acquiring reconstructed CT images to obtain…

Quantum Physics · Physics 2024-09-17 Kyungtaek Jun

Leveraging quantum computers for optimization problems holds promise across various application domains. Nevertheless, utilizing respective quantum computing solvers requires describing the optimization problem according to the Quadratic…

Quantum Physics · Physics 2025-10-15 Deborah Volpe , Nils Quetschlich , Mariagrazia Graziano , Giovanna Turvani , Robert Wille

The vehicle routing problem with time windows (VRPTW) is a common optimization problem faced within the logistics industry. In this work, we explore the use of a previously-introduced qubit encoding scheme to reduce the number of binary…

Quantum Physics · Physics 2023-09-20 Ioannis D. Leonidas , Alexander Dukakis , Benjamin Tan , Dimitris G. Angelakis