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Segmentation is a fundamental task in medical image analysis. The clinical interest is often to measure the volume of a structure. To evaluate and compare segmentation methods, the similarity between a segmentation and a predefined ground…

Image and Video Processing · Electrical Eng. & Systems 2020-10-09 Jeroen Bertels , David Robben , Dirk Vandermeulen , Paul Suetens

The development of automatic segmentation techniques for medical imaging tasks requires assessment metrics to fairly judge and rank such approaches on benchmarks. The Dice Similarity Coefficient (DSC) is a popular choice for comparing the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-13 Vatsal Raina , Nataliia Molchanova , Mara Graziani , Andrey Malinin , Henning Muller , Meritxell Bach Cuadra , Mark Gales

Lesion segmentation on computed tomography (CT) scans is an important step for precisely monitoring changes in lesion/tumor growth. This task, however, is very challenging since manual segmentation is prohibitively time-consuming,…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Vatsal Agarwal , Youbao Tang , Jing Xiao , Ronald M. Summers

Magnetic resonance images (MRI) play an important role in supporting and substituting clinical information in the diagnosis of multiple sclerosis (MS) disease by presenting lesion in brain MR images. In this paper, an algorithm for MS…

Image and Video Processing · Electrical Eng. & Systems 2018-04-11 Saba Heidari Gheshlaghi , Abolfazl Madani , AmirAbolfazl Suratgar , Fardin Faraji

Deep neural networks for medical image segmentation often produce overconfident results misaligned with empirical observations. Such miscalibration, challenges their clinical translation. We propose to use marginal L1 average calibration…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Theodore Barfoot , Luis Garcia-Peraza-Herrera , Ben Glocker , Tom Vercauteren

Fully convolutional neural networks (FCNs), and in particular U-Nets, have achieved state-of-the-art results in semantic segmentation for numerous medical imaging applications. Moreover, batch normalization and Dice loss have been used…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Alireza Mehrtash , William M. Wells , Clare M. Tempany , Purang Abolmaesumi , Tina Kapur

Loss functions are error metrics that quantify the difference between a prediction and its corresponding ground truth. Fundamentally, they define a functional landscape for traversal by gradient descent. Although numerous loss functions…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Chaitanya Kaul , Nick Pears , Hang Dai , Roderick Murray-Smith , Suresh Manandhar

In response to the growing importance of geospatial data, its analysis including semantic segmentation becomes an increasingly popular task in computer vision today. Convolutional neural networks are powerful visual models that yield…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Alexey Bokhovkin , Evgeny Burnaev

Detecting lesions in Computed Tomography (CT) scans is a challenging task in medical image processing due to the diverse types, sizes, and locations of lesions. Recently, various one-stage and two-stage framework networks have been…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Di Fan , Heng Yu , Zhiyuan Xu

Segmentation of Hypoxic-Ischemic Encephalopathy (HIE) lesions in neonatal MRI is a crucial but challenging task due to diffuse multifocal lesions with varying volumes and the limited availability of annotated HIE lesion datasets. Using the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Annayah Usman , Abdul Haseeb , Tahir Syed

Automated medical image segmentation is an essential task to aid/speed up diagnosis and treatment procedures in clinical practices. Deep convolutional neural networks have exhibited promising performance in accurate and automatic seminal…

Medical Physics · Physics 2022-03-08 Reza Karimzadeh , Emad Fatemizadeh , Hossein Arabi

Finding small lesions is very challenging due to lack of noticeable features, severe class imbalance, as well as the size itself. One approach to improve small lesion segmentation is to reduce the region of interest and inspect it at a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-01 Seung Yeon Shin , Thomas C. Shen , Stephen A. Wank , Ronald M. Summers

Semantic instance segmentation remains a challenging task. In this work we propose to tackle the problem with a discriminative loss function, operating at the pixel level, that encourages a convolutional network to produce a representation…

Computer Vision and Pattern Recognition · Computer Science 2017-08-10 Bert De Brabandere , Davy Neven , Luc Van Gool

The loss function is a key component in deep learning models. A commonly used loss function for classification is the cross entropy loss, which is a simple yet effective application of information theory for classification problems. Based…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Zeyu Song , Dongliang Chang , Zhanyu Ma , Xiaoxu Li , Zheng-Hua Tan

This paper presents a deep learning method using Natural Language Processing (NLP) techniques, to distinguish between Mild Cognitive Impairment (MCI) and Normal Cognitive (NC) conditions in older adults. We propose a framework that analyzes…

Computation and Language · Computer Science 2024-02-06 Ali Pourramezan Fard , Mohammad H. Mahoor , Muath Alsuhaibani , Hiroko H. Dodgec

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Designing proper loss functions for vision tasks has been a long-standing research direction to advance the capability of existing models. For object detection, the well-established classification and regression loss functions have been…

Computer Vision and Pattern Recognition · Computer Science 2021-02-10 Peidong Liu , Gengwei Zhang , Bochao Wang , Hang Xu , Xiaodan Liang , Yong Jiang , Zhenguo Li

This paper presents a study on the soft-Dice loss, one of the most popular loss functions in medical image segmentation, for situations where noise is present in target labels. In particular, the set of optimal solutions are characterized…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Marcus Nordström , Henrik Hult , Atsuto Maki , Fredrik Löfman

We propose two novel loss functions, Multiplicative Loss and Confidence-Adaptive Multiplicative Loss, for semantic segmentation in medical and cellular images. Although Cross Entropy and Dice Loss are widely used, their additive combination…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuto Yokoi , Kazuhiro Hotta