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Synthetic tabular data are often evaluated by distributional similarity, privacy distance, or train-on-synthetic-test-on-real predictive performance, but these criteria do not ensure validity for causal inference. We show that fully…

Methodology · Statistics 2026-05-12 Yichen Xu

Ensuring the generalisability of clinical machine learning (ML) models across diverse healthcare settings remains a significant challenge due to variability in patient demographics, disease prevalence, and institutional practices. Existing…

Machine Learning · Computer Science 2025-04-30 Bradley Segal , Joshua Fieggen , David Clifton , Lei Clifton

Chest x-rays are a vital tool in the workup of many patients. Similar to most medical imaging modalities, they are profoundly multi-modal and are capable of visualising a variety of combinations of conditions. There is an ever pressing need…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Bradley Segal , David M. Rubin , Grace Rubin , Adam Pantanowitz

Large and well-annotated datasets are essential for advancing deep learning applications, however often costly or impossible to obtain by a single entity. In many areas, including the medical domain, approaches relying on data sharing have…

Machine Learning · Computer Science 2024-08-02 Francesco Di Salvo , David Tafler , Sebastian Doerrich , Christian Ledig

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

Genomics · Quantitative Biology 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

The machine learning community has mainly relied on real data to benchmark algorithms as it provides compelling evidence of model applicability. Evaluation on synthetic datasets can be a powerful tool to provide a better understanding of a…

Machine Learning · Computer Science 2022-11-01 Florence Regol , Anja Kroon , Mark Coates

Inverse design, which seeks to find optimal parameters for a target output, is a central challenge in engineering. Surrogate-based optimization (SBO) has become a standard approach, yet it is fundamentally structured to converge to a…

Machine Learning · Computer Science 2025-10-08 Muhammad Arif Hakimi Zamrai

Variational AutoEncoders (VAEs) are powerful generative models that merge elements from statistics and information theory with the flexibility offered by deep neural networks to efficiently solve the generation problem for high dimensional…

Machine Learning · Computer Science 2021-03-02 A. Asperti , D. Evangelista , E. Loli Piccolomini

Electrocardiogram (ECG) datasets tend to be highly imbalanced due to the scarcity of abnormal cases. Additionally, the use of real patients' ECGs is highly regulated due to privacy issues. Therefore, there is always a need for more ECG…

Machine Learning · Computer Science 2022-08-25 Edmond Adib , Fatemeh Afghah , John J. Prevost

In optimizing performance and extending the lifespan of lithium batteries, accurate state prediction is pivotal. Traditional regression and classification methods have achieved some success in battery state prediction. However, the efficacy…

Machine Learning · Computer Science 2024-10-07 Lidang Jiang , Changyan Hu , Sibei Ji , Hang Zhao , Junxiong Chen , Ge He

Insufficient training data is a major bottleneck for most deep learning practices, not least in medical imaging where data is difficult to collect and publicly available datasets are scarce due to ethics and privacy. This work investigates…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Gabriel Eilertsen , Apostolia Tsirikoglou , Claes Lundström , Jonas Unger

The proliferation of generative models, such as Generative Adversarial Networks (GANs), Diffusion Models, and Variational Autoencoders (VAEs), has enabled the synthesis of high-quality multimedia data. However, these advancements have also…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Arpan Mahara , Naphtali Rishe

The data-centric construction of inexpensive surrogates for fine-grained, physical models has been at the forefront of computational physics due to its significant utility in many-query tasks such as uncertainty quantification. Recent…

Machine Learning · Statistics 2021-03-17 Maximilian Rixner , Phaedon-Stelios Koutsourelakis

Tuning curves characterizing the response selectivities of biological neurons often exhibit large degrees of irregularity and diversity across neurons. Theoretical network models that feature heterogeneous cell populations or random…

Quantitative Methods · Quantitative Biology 2017-07-20 Takafumi Arakaki , G. Barello , Yashar Ahmadian

Structured output representation is a generative task explored in computer vision that often times requires the mapping of low dimensional features to high dimensional structured outputs. Losses in complex spatial information in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Mohamed Debbagh

Eligibility criteria (EC) are essential for clinical trial design, yet drafting them remains a time-intensive and cognitively demanding task for clinicians. Existing automated approaches often fall at two extremes either requiring highly…

Artificial Intelligence · Computer Science 2026-02-03 Trisha Das , Katherine Kero , Dorinda Schumann , Tracy Ohrt , Sanjit Singh Batra , Gregory D Lyng , Robert E. Tillman

Sampling-based motion planning under task constraints is challenging because the null-measure constraint manifold in the configuration space makes rejection sampling extremely inefficient, if not impossible. This paper presents a…

Robotics · Computer Science 2022-04-15 Cihan Acar , Keng Peng Tee

Generative models are undoubtedly a hot topic in Artificial Intelligence, among which the most common type is Generative Adversarial Networks (GANs). These architectures let one synthesise artificial datasets by implicitly modelling the…

Machine Learning · Computer Science 2020-07-07 Francisco J. Ibarrola , Nishant Ravikumar , Alejandro F. Frangi

Generative Adversarial Networks (GANs) have shown remarkable success as a framework for training models to produce realistic-looking data. In this work, we propose a Recurrent GAN (RGAN) and Recurrent Conditional GAN (RCGAN) to produce…

Machine Learning · Statistics 2017-12-05 Cristóbal Esteban , Stephanie L. Hyland , Gunnar Rätsch

Existing image generation models face critical challenges regarding the trade-off between computation and fidelity. Specifically, models relying on a pretrained Variational Autoencoder (VAE) suffer from information loss, limited detail, and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Chenrui Ma , Xi Xiao , Tianyang Wang , Xiao Wang , Yanning Shen
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