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Clinicians compare breast DCE-MRI after neoadjuvant chemotherapy (NAC) with pre-treatment scans to evaluate the response to NAC. Clinical evidence supports that accurate longitudinal deformable registration without deforming treated tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Luyi Han , Tao Tan , Tianyu Zhang , Yuan Gao , Xin Wang , Valentina Longo , Sofía Ventura-Díaz , Anna D'Angelo , Jonas Teuwen , Ritse Mann

Style transfer in DCE-MRI is a challenging task due to large variations in contrast enhancements across different tissues and time. Current unsupervised methods fail due to the wide variety of contrast enhancement and motion between the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-23 Adam G. Tattersall , Keith A. Goatman , Lucy E. Kershaw , Scott I. K. Semple , Sonia Dahdouh

Introduction: Quantification of dynamic contrast-enhanced (DCE)-MRI has the potential to provide valuable clinical information, but robust pharmacokinetic modeling remains a challenge for clinical adoption. Methods: A 7-layer neural network…

Medical Physics · Physics 2024-05-22 Ouri Cohen , Soudabeh Kargar , Sungmin Woo , Alberto Vargas , Ricardo Otazo

Accurate segmentation of laryngo-pharyngeal tumors is crucial for precise diagnosis and effective treatment planning. However, traditional single-modality imaging methods often fall short of capturing the complex anatomical and pathological…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Junhao Wu , Yun Li , Junhao Li , Jingliang Bian , Xiaomao Fan , Wenbin Lei , Ruxin Wang

Breast ultrasound imaging is a valuable tool for early breast cancer detection, but automated tumor segmentation is challenging due to inherent noise, variations in scale of lesions, and fuzzy boundaries. To address these challenges, we…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Muhammad Azeem Aslam , Asim Naveed , Nisar Ahmed

Dynamic Magnetic Resonance Imaging (MRI) is a crucial non-invasive method used to capture the movement of internal organs and tissues, making it a key tool for medical diagnosis. However, dynamic MRI faces a major challenge: long…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Tamir Shor , Chaim Baskin , Alex Bronstein

Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…

Medical Physics · Physics 2020-11-26 Yu-ichi Takamizu , Masayuki Umemura , Hidenobu Yajima , Makito Abe , Yoko Hoshi

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is used to study microvascular structure and tissue perfusion. In DCE-MRI a bolus of gadolinium based contrast agent is injected into the blood stream and spatiotemporal changes…

Medical Physics · Physics 2020-09-22 Matti Hanhela , Mikko Kettunen , Olli Gröhn , Marko Vauhkonen , Ville Kolehmainen

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

Cancer is an abnormal growth with potential to invade locally and metastasize to distant organs. Accurate auto-segmentation of the tumor and surrounding normal tissues is required for radiotherapy treatment plan optimization. Recent…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Syed Haider Ali , Asrar Ahmad , Muhammad Ali , Asifullah Khan , Nadeem Shaukat

Early assessment of tumor therapeutic response is an important topic in precision medicine to optimize personalized treatment regimens and reduce unnecessary toxicity, cost, and delay. Although diffusion MRI (dMRI) has shown potential to…

Medical Physics · Physics 2024-08-06 Diwei Shi , Sisi Li , Fan Liu , Xiaoyu Jiang , Lei Wu , Li Chen , Quanshui Zheng , Haihua Bao , Hua Guo , Junzhong Xu

Accurate tumor segmentation is crucial for cancer diagnosis and treatment. While foundation models have advanced general-purpose segmentation, existing methods still struggle with: (1) limited incorporation of medical priors, (2) imbalance…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Runqi Meng , Sifan Song , Pengfei Jin , Yujin Oh , Lin Teng , Yulin Wang , Yiqun Sun , Ling Chen , Xiang Li , Quanzheng Li , Ning Guo , Dinggang Shen

Dynamic contrast-enhanced (DCE) cardiac magnetic resonance imaging (CMRI) is a widely used modality for diagnosing myocardial blood flow (perfusion) abnormalities. During a typical free-breathing DCE-CMRI scan, close to 300 time-resolved…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Dilek M. Yalcinkaya , Khalid Youssef , Bobak Heydari , Orlando Simonetti , Rohan Dharmakumar , Subha Raman , Behzad Sharif

In the quantitative analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) compartment models allow to describe the uptake of contrast medium with biological meaningful kinetic parameters. As simple models often fail to…

Methodology · Statistics 2020-05-04 Julia C. Sommer , Volker J. Schmid

Tumor vascularity detection and quantification are of high relevance in the assessment of cancer lesions not only for disease diagnostics but for therapy considerations and monitoring. The present work addressed the quantification of…

Medical Physics · Physics 2023-05-23 Jhonalbert Aponte , Álvaro Ruiz , Jacksson Sánchez , Miguel Martín-Landrove

Dynamic Contrast-enhanced magnetic resonance imaging (DCE-MRI) is a tissue perfusion imaging technique. Some versatile free-breathing DCE-MRI techniques combining compressed sensing (CS) and parallel imaging with golden-angle radial…

Medical Physics · Physics 2020-07-08 Yuhan Hu , Xinlin Zhang , Li Feng , Dicheng Chen , Zhiping Yan , Xiaoyong Shen , Gen Yan , Lin Ou-yang , Xiaobo Qu

In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain…

Computer Vision and Pattern Recognition · Computer Science 2018-08-17 Mikael Agn , Per Munck af Rosenschöld , Oula Puonti , Michael J. Lundemann , Laura Mancini , Anastasia Papadaki , Steffi Thust , John Ashburner , Ian Law , Koen Van Leemput

Automatic brain tumor segmentation plays an important role for diagnosis, surgical planning and treatment assessment of brain tumors. Deep convolutional neural networks (CNNs) have been widely used for this task. Due to the relatively small…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Guotai Wang , Wenqi Li , Sebastien Ourselin , Tom Vercauteren

Magnetic resonance imaging (MRI) provides varying tissue contrast images of internal organs based on a strong magnetic field. Despite the non-invasive advantage of MRI in frequent imaging, the low contrast MR images in the target area make…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Mohammad Hamghalam , Baiying Lei , Tianfu Wang