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Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

Artificial Intelligence · Computer Science 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Multi-Task Learning (MTL) is a learning paradigm in machine learning and its aim is to leverage useful information contained in multiple related tasks to help improve the generalization performance of all the tasks. In this paper, we give a…

Machine Learning · Computer Science 2021-03-30 Yu Zhang , Qiang Yang

Accurately recognizing health-related conditions from wearable data is crucial for improved healthcare outcomes. To improve the recognition accuracy, various approaches have focused on how to effectively fuse information from multiple…

Machine Learning · Computer Science 2022-02-18 Huiyuan Yang , Han Yu , Kusha Sridhar , Thomas Vaessen , Inez Myin-Germeys , Akane Sano

Multi-task learning is to improve the performance of the model by transferring and exploiting common knowledge among tasks. Existing MTL works mainly focus on the scenario where label sets among multiple tasks (MTs) are usually the same,…

Machine Learning · Computer Science 2022-01-10 Quan Feng , Songcan Chen

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

Federated Learning (FL) enables joint training across distributed clients using their local data privately. Federated Multi-Task Learning (FMTL) builds on FL to handle multiple tasks, assuming model congruity that identical model…

Computer Vision and Pattern Recognition · Computer Science 2024-03-01 Yuxiang Lu , Suizhi Huang , Yuwen Yang , Shalayiding Sirejiding , Yue Ding , Hongtao Lu

Physical activity is crucial for human health. With the increasing availability of large-scale mobile health data, strong associations have been found between physical activity and various diseases. However, accurately capturing this…

Applications · Statistics 2025-01-03 Xiaojing Sun , Bingxin Zhao , Fei Xue

Reinforcement learning (RL) in healthcare has had mixed results, with reward sparsity, unreliable off-policy evaluation, and deployment-simulation gap as recurring failure modes. We argue that chronic disease management is structurally a…

Machine Learning · Computer Science 2026-05-12 Prabhjot Singh , Abhishek Gupta , Chris Betz , Abe Flansburg , Brett Ives , Sudeep Lama , Jung Hoon Son

Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…

Artificial Intelligence · Computer Science 2024-12-24 Francisco de Arriba-Pérez , Silvia García-Méndez

Depression is a common disease worldwide. It is difficult to diagnose and continues to be underdiagnosed. Because depressed patients constantly share their symptoms, major life events, and treatments on social media, researchers are turning…

Computation and Language · Computer Science 2025-10-27 Wenli Zhang , Jiaheng Xie , Zhu Zhang , Xiang Liu

Object detection, segmentation and classification are three common tasks in medical image analysis. Multi-task deep learning (MTL) tackles these three tasks jointly, which provides several advantages saving computing time and resources and…

Computer Vision and Pattern Recognition · Computer Science 2019-06-06 Fei Gao , Hyunsoo Yoon , Teresa Wu , Xianghua Chu

Machine learning approaches for Alzheimer's disease (AD) diagnosis face a fundamental challenges. Clinical assessments are expensive and invasive, leaving ground truth labels available for only a fraction of neuroimaging datasets. We…

Machine Learning · Computer Science 2026-03-23 Alireza Moayedikia , Sara Fin

Over the past decade a wide spectrum of machine learning models have been developed to model the neurodegenerative diseases, associating biomarkers, especially non-intrusive neuroimaging markers, with key clinical scores measuring the…

Machine Learning · Computer Science 2018-03-02 Mengying Sun , Inci M. Baytas , Liang Zhan , Zhangyang Wang , Jiayu Zhou

Federated multi-task learning (FMTL) aims to simultaneously learn multiple related tasks across clients without sharing sensitive raw data. However, in the decentralized setting, existing FMTL frameworks are limited in their ability to…

Machine Learning · Computer Science 2025-06-10 Chaouki Ben Issaid , Praneeth Vepakomma , Mehdi Bennis

Human Activity Recognition (HAR) is a fundamental technology for numerous human - centered intelligent applications. Although deep learning methods have been utilized to accelerate feature extraction, issues such as multimodal data mixing,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Ying Yu , Siyao Li , Yixuan Jiang , Hang Xiao , Jingxi Long , Haotian Tang , Hanyu Liu , Chao Li

Recently, the application of deep learning models to diagnose neuropsychiatric diseases from brain imaging data has received more and more attention. However, in practice, exploring interactions in brain functional connectivity based on…

Machine Learning · Computer Science 2022-06-29 Sartaj Ahmed Salman , Zhichao Lian , Milad Taleby Ahvanooey , Hiroki Takahashi , Yuduo Zhang

Epilepsy is a chronic neurological disorder with a significant prevalence. However, there is still no adequate technological support to enable epilepsy detection and continuous outpatient monitoring in everyday life. Hyperdimensional (HD)…

Neural and Evolutionary Computing · Computer Science 2024-04-30 Una Pale , Tomas Teijeiro , David Atienza