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Related papers: Beyond Generative AI: World Models for Clinical Pr…

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Generative Artificial Intelligence (GenAI) is taking the world by storm. It promises transformative opportunities for advancing and disrupting existing practices, including healthcare. From large language models (LLMs) for clinical note…

Artificial Intelligence · Computer Science 2025-10-29 Gang Chen , Changshuo Liu , Gene Anne Ooi , Marcus Tan , Zhongle Xie , Jianwei Yin , James Wei Luen Yip , Wenqiao Zhang , Jiaqi Zhu , Beng Chin Ooi

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

Generative artificial intelligence (AI) is rapidly transforming medical imaging by enabling capabilities such as data synthesis, image enhancement, modality translation, and spatiotemporal modeling. This review presents a comprehensive and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Xuanru Zhou , Cheng Li , Shuqiang Wang , Ye Li , Tao Tan , Hairong Zheng , Shanshan Wang

Counterfactual generation offers a principled framework for simulating hypothetical changes in medical imaging, with potential applications in understanding disease mechanisms and generating physiologically plausible data. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Pengwei Sun , Wei Peng , Lun Yu Li , Yixin Wang , Kilian M. Pohl

This review introduces the transformative potential of generative Artificial Intelligence (AI) and foundation models, including large language models (LLMs), for health technology assessment (HTA). We explore their applications in four…

Machine Learning · Computer Science 2024-09-24 Rachael Fleurence , Jiang Bian , Xiaoyan Wang , Hua Xu , Dalia Dawoud , Mitch Higashi , Jagpreet Chhatwal

Generative medical AI now appears fluent and knowledgeable enough to resemble clinical intelligence, encouraging the belief that scaling will make it safe. But clinical reasoning is not text generation. It is a responsibility-bound process…

Artificial Intelligence · Computer Science 2026-02-02 Vaibhav Ram S. V. N. S , Swetanshu Agrawal , Samudra Banerjee , Abdul Muhsin

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

World models have emerged as a unifying paradigm for learning latent dynamics, simulating counterfactual futures, and supporting planning under uncertainty. In this paper, we argue that computational epidemiology is a natural and…

Machine Learning · Computer Science 2026-04-14 Zeeshan Memon , Yiqi Su , Christo Kurisummoottil Thomas , Walid Saad , Liang Zhao , Naren Ramakrishnan

Clinical decision-making in oncology requires predicting dynamic disease evolution, a task current static AI predictors cannot perform. While world models (WMs) offer a paradigm for generative prediction, existing medical applications…

Machine Learning · Computer Science 2026-03-30 Tianxingjian Ding , Yuanhao Zou , Chen Chen , Mubarak Shah , Yu Tian

A world model is an AI system that simulates how an environment evolves under actions, enabling planning through imagined futures rather than reactive perception. Current world models, however, suffer from visual conflation: the mistaken…

Artificial Intelligence · Computer Science 2026-01-23 Zhikang Chen , Tingting Zhu

Generative modeling has become a central paradigm in protein research, extending machine learning beyond structure prediction toward sequence design, backbone generation, inverse folding, and biomolecular interaction modeling. However, the…

Machine Learning · Computer Science 2026-03-30 Senura Hansaja Wanasekara , Minh-Duong Nguyen , Xiaochen Liu , Nguyen H. Tran , Ken-Tye Yong

Ophthalmic decision-making depends on subtle lesion-scale cues interpreted across multimodal imaging and over time, yet most medical foundation models remain static and degrade under modality and acquisition shifts. Here we introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ziyu Gao , Xinyuan Wu , Xiaolan Chen , Zhuoran Liu , Ruoyu Chen , Bowen Liu , Bingjie Yan , Zhenhan Wang , Kai Jin , Jiancheng Yang , Yih Chung Tham , Mingguang He , Danli Shi

Embodied AI requires agents that perceive, act, and anticipate how actions reshape future world states. World models serve as internal simulators that capture environment dynamics, enabling forward and counterfactual rollouts to support…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Xinqing Li , Xin He , Le Zhang , Min Wu , Xiaoli Li , Yun Liu

Healthcare and medicine are multimodal disciplines that deal with multimodal data for reasoning and diagnosing multiple diseases. Although some multimodal reasoning models have emerged for reasoning complex tasks in scientific domains,…

Artificial Intelligence · Computer Science 2025-09-16 Susanta Mitra

World Models help Artificial Intelligence (AI) predict outcomes, reason about its environment, and guide decision-making. While widely used in reinforcement learning, they lack the structured, adaptive representations that even young…

Artificial Intelligence · Computer Science 2025-03-20 Javier Del Ser , Jesus L. Lobo , Heimo Müller , Andreas Holzinger

With the continuous advancement of technology, artificial intelligence has significantly impacted various fields, particularly healthcare. Generative models, a key AI technology, have revolutionized medical image generation, data analysis,…

Machine Learning · Computer Science 2024-10-10 Yuan Sun , Jorge Ortiz

Generative artificial intelligence (AI) models, such as diffusion models and OpenAI's ChatGPT, are transforming medicine by enhancing diagnostic accuracy and automating clinical workflows. The field has advanced rapidly, evolving from…

Artificial Intelligence · Computer Science 2025-08-28 Lukas Buess , Matthias Keicher , Nassir Navab , Andreas Maier , Soroosh Tayebi Arasteh

This study presents a novel framework for counterfactual user behavior forecasting that combines structural causal models with transformer-based generative artificial intelligence. To model fictitious situations, the method creates causal…

Machine Learning · Computer Science 2025-11-12 Dharmateja Priyadarshi Uddandarao , Ravi Kiran Vadlamani

World models have recently re-emerged as a central paradigm for embodied intelligence, robotics, autonomous driving, and model-based reinforcement learning. However, current world model research is often dominated by three partially…

Artificial Intelligence · Computer Science 2026-05-27 Sen Cui , Jingheng Ma

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang
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