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Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

Robotics · Computer Science 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

Reasoning LLMs such as OpenAI o1, o3 and DeepSeek R1 have made significant progress in mathematics and coding, yet find challenging advanced tasks such as International Mathematical Olympiad (IMO) combinatorics problems, Abstraction and…

While large multimodal models (LMMs) have demonstrated strong performance across various Visual Question Answering (VQA) tasks, certain challenges require complex multi-step reasoning to reach accurate answers. One particularly challenging…

Medical vision-language models (VLMs) and AI agents have made significant progress in learning to analyze and reason about clinical images. However, existing medical visual question answering (VQA) benchmarks collapse model capabilities…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yixiong Chen , Wenjie Xiao , Pedro R. A. S. Bassi , Boyan Wang , Liang He , Xinze Zhou , Sezgin Er , Ibrahim Ethem Hamamci , Zongwei Zhou , Alan Yuille

The emergence of Multimodal Large Language Models (MLLMs) that integrate vision and language modalities has unlocked new potentials for scientific reasoning, outperforming prior benchmarks in both natural language and coding domains.…

Computational Engineering, Finance, and Science · Computer Science 2025-05-27 Sifan Wu , Huan Zhang , Yizhan Li , Farshid Effaty , Amirreza Ataei , Bang Liu

Recent multimodal large language models (MLLMs) show strong capabilities in visual-language reasoning, yet their performance on ultra-high-resolution imagery remains largely unexplored. Existing visual question answering (VQA) benchmarks…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Siqi Li , Xinyu Cai , Jianbiao Mei , Nianchen Deng , Pinlong Cai , Licheng Wen , Yufan Shen , Xuemeng Yang , Botian Shi , Yong Liu

Building robots that can perceive, reason, and act in dynamic, unstructured environments remains a core challenge. Recent embodied systems often adopt a dual-system paradigm, where System 2 handles high-level reasoning while System 1…

Multimodal Entity Linking (MEL) aims to associate textual and visual mentions with entities in a multimodal knowledge graph. Despite its importance, current methods face challenges such as incomplete contextual information, coarse…

Computation and Language · Computer Science 2025-08-25 Fang Wang , Tianwei Yan , Zonghao Yang , Minghao Hu , Jun Zhang , Zhunchen Luo , Xiaoying Bai

We introduce Orion, a visual agent that integrates vision-based reasoning with tool-augmented execution to achieve powerful, precise, multi-step visual intelligence across images, video, and documents. Unlike traditional vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 N Dinesh Reddy , Dylan Snyder , Lona Kiragu , Mirajul Mohin , Shahrear Bin Amin , Sudeep Pillai

Large language models (LLMs) have shown impressive performance on complex reasoning by leveraging chain-of-thought (CoT) prompting to generate intermediate reasoning chains as the rationale to infer the answer. However, existing CoT studies…

Computation and Language · Computer Science 2024-05-21 Zhuosheng Zhang , Aston Zhang , Mu Li , Hai Zhao , George Karypis , Alex Smola

Evolutionary multi-objective optimization (EMO) algorithms have been demonstrated to be effective in solving multi-criteria decision-making problems. In real-world applications, analysts often employ several algorithms concurrently and…

Neural and Evolutionary Computing · Computer Science 2024-08-09 Yansong Huang , Zherui Zhang , Ao Jiao , Yuxin Ma , Ran Cheng

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Metal-organic frameworks (MOFs) offer a vast design space, and as such, computational simulations play a critical role in predicting their structural and physicochemical properties. However, MOF simulations remain difficult to access…

Artificial Intelligence · Computer Science 2026-04-01 Jaewoong Lee , Taeun Bae , Jihan Kim

In this work, we present a network-specific approach for predicting brain responses to complex multimodal movies, leveraging the Yeo 7-network parcellation of the Schaefer atlas. Rather than treating the brain as a homogeneous system, we…

Neurons and Cognition · Quantitative Biology 2025-10-28 Andrea Corsico , Giorgia Rigamonti , Simone Zini , Luigi Celona , Paolo Napoletano

Automated knowledge discovery from trending chemical literature is essential for more efficient biomedical research. How to extract detailed knowledge about chemical reactions from the core chemistry literature is a new emerging challenge…

Computation and Language · Computer Science 2021-08-31 Chenkai Sun , Weijiang Li , Jinfeng Xiao , Nikolaus Nova Parulian , ChengXiang Zhai , Heng Ji

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Computation and Language · Computer Science 2025-03-21 Xiangru Tang , Daniel Shao , Jiwoong Sohn , Jiapeng Chen , Jiayi Zhang , Jinyu Xiang , Fang Wu , Yilun Zhao , Chenglin Wu , Wenqi Shi , Arman Cohan , Mark Gerstein

This paper presents a summary of the VQualA 2025 Challenge on Visual Quality Comparison for Large Multimodal Models (LMMs), hosted as part of the ICCV 2025 Workshop on Visual Quality Assessment. The challenge aims to evaluate and enhance…

Large language models (LLMs) hold considerable potential for advancing scientific discovery, yet systematic assessment of their dynamic reasoning in real-world research remains limited. Current scientific evaluation benchmarks predominantly…

Computation and Language · Computer Science 2026-03-27 Taolin Han , Shuang Wu , Jinghang Wang , Yuhao Zhou , Renquan Lv , Bing Zhao , Wei Hu

Large Language Models (LLMs) and Vision Language Models (VLMs) possess extensive knowledge and exhibit promising reasoning abilities, however, they still struggle to perform well in complex, dynamic environments. Real-world tasks require…

While large language models (LLMs) have demonstrated remarkable versatility across a wide range of general tasks, their effectiveness often diminishes in domain-specific applications due to inherent knowledge gaps. Moreover, their…

Artificial Intelligence · Computer Science 2025-11-21 Hanzhi Yan , Qin Lu , Xianqiao Wang , Xiaoming Zhai , Tianming Liu , He Li
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