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The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Machine Learning · Computer Science 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

Background: Social support (SS) and social isolation (SI) are social determinants of health (SDOH) associated with psychiatric outcomes. In electronic health records (EHRs), individual-level SS/SI is typically documented as narrative…

Natural language generation (NLG) is the key technology to achieve generative artificial intelligence (AI). With the breakthroughs in large language models (LLMs), NLG has been widely used in various medical applications, demonstrating the…

Computation and Language · Computer Science 2025-05-08 Mengxian Lyu , Xiaohan Li , Ziyi Chen , Jinqian Pan , Cheng Peng , Sankalp Talankar , Yonghui Wu

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

De-identification in the healthcare setting is an application of NLP where automated algorithms are used to remove personally identifying information of patients (and, sometimes, providers). With the recent rise of generative large language…

Computation and Language · Computer Science 2025-09-19 Kiana Aghakasiri , Noopur Zambare , JoAnn Thai , Carrie Ye , Mayur Mehta , J. Ross Mitchell , Mohamed Abdalla

Large Language Models (LLMs) have remarkable capabilities across NLP tasks. However, their performance in multilingual contexts, especially within the mental health domain, has not been thoroughly explored. In this paper, we evaluate…

Computation and Language · Computer Science 2026-02-03 Nishat Raihan , Sadiya Sayara Chowdhury Puspo , Ana-Maria Bucur , Stevie Chancellor , Marcos Zampieri

Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Computation and Language · Computer Science 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu

Large Language Models (LLMs) recently achieved great success in medical text summarization by simply using in-context learning. However, these recent efforts do not perform fine-grained evaluations under difficult settings where LLMs might…

Computation and Language · Computer Science 2026-04-22 Gunjan Balde , Soumyadeep Roy , Mainack Mondal , Niloy Ganguly

Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

Automated clinical text anonymization has the potential to unlock the widespread sharing of textual health data for secondary usage while assuring patient privacy and safety. Despite the proposal of many complex and theoretically successful…

Computation and Language · Computer Science 2024-06-05 David Pissarra , Isabel Curioso , João Alveira , Duarte Pereira , Bruno Ribeiro , Tomás Souper , Vasco Gomes , André V. Carreiro , Vitor Rolla

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Automating data extraction from clinical documents offers significant potential to improve efficiency in healthcare settings, yet deploying Natural Language Processing (NLP) solutions presents practical challenges. Drawing upon our…

Computation and Language · Computer Science 2025-08-18 Lovedeep Gondara , Gregory Arbour , Raymond Ng , Jonathan Simkin , Shebnum Devji

The advancement of Large Language Models (LLMs) has significantly impacted biomedical Natural Language Processing (NLP), enhancing tasks such as named entity recognition, relation extraction, event extraction, and text classification. In…

Computation and Language · Computer Science 2025-03-04 Zaifu Zhan , Shuang Zhou , Huixue Zhou , Jiawen Deng , Yu Hou , Jeremy Yeung , Rui Zhang

The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

The objective of our study is to determine whether using English tools to extract and normalize French medical concepts on translations provides comparable performance to French models trained on a set of annotated French clinical notes. We…

Computation and Language · Computer Science 2023-06-06 Christel Gérardin , Yuhan Xiong , Perceval Wajsbürt , Fabrice Carrat , Xavier Tannier
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