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As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Human-Computer Interaction · Computer Science 2026-05-19 Zeshan Hussain , Barbara D. Lam , Fernando A. Acosta-Perez , Irbaz Bin Riaz , Maia Jacobs , Andrew J. Yee , David Sontag

Reservoir computing (RC) establishes the basis for the processing of time-series data by exploiting the high-dimensional spatiotemporal response of a recurrent neural network to an input signal. In particular, RC trains only the output…

Machine Learning · Computer Science 2025-10-17 Hayato Nihei , Sou Nobukawa , Yusuke Sakemi , Kazuyuki Aihara

The advent of wide-field sky surveys has led to the growth of transient and variable source discoveries. The data deluge produced by these surveys has necessitated the use of machine learning (ML) and deep learning (DL) algorithms to sift…

Artificial intelligence (AI) has brought tremendous impacts on biomedical sciences from academic researches to clinical applications, such as in biomarkers' detection and diagnosis, optimization of treatment, and identification of new…

Quantitative Methods · Quantitative Biology 2023-03-14 Yu-Jia An , Sheng-Chen Bai , Lin Cheng , Xiao-Guang Li , Cheng-en Wang , Xiao-Dong Han , Gang Su , Shi-Ju Ran , Cong Wang

Machine learning (ML) is revolutionising drug discovery by expediting the prediction of small molecule properties essential for developing new drugs. These properties -- including absorption, distribution, metabolism and excretion (ADME)--…

Machine Learning · Computer Science 2024-08-02 Alex G. C. de Sá , David B. Ascher

While machine learning (ML) includes a valuable array of tools for analyzing biomedical data, significant time and expertise is required to assemble effective, rigorous, and unbiased pipelines. Automated ML (AutoML) tools seek to facilitate…

The prediction of high-resolution hourly traffic volumes of a given roadway is essential for transportation planning. Traditionally, Automatic Traffic Recorders (ATR) are used to collect this hourly volume data. These large datasets are…

Applications · Statistics 2019-09-26 MD Zadid Khan , Sakib Mahmud Khan , Mashrur Chowdhury , Kakan Dey

Statistical power is often a concern for clustered RCTs due to variance inflation from design effects and the high cost of adding study clusters (such as hospitals, schools, or communities). While covariate pre-specification is the…

Methodology · Statistics 2020-05-07 Peter Z. Schochet

Compositional disorder is common in crystal compounds. In these compounds, some atoms are randomly distributed at some crystallographic sites. For such compounds, randomness forms many non-identical independent structures. Thus, calculating…

Materials Science · Physics 2022-12-23 Mostafa Yaghoobi , Mojtaba Alaei

Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

Quantitative Methods · Quantitative Biology 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

It is important to develop sustainable processes in materials science and manufacturing that are environmentally friendly. AI can play a significant role in decision support here as evident from our earlier research leading to tools…

Artificial Intelligence · Computer Science 2023-03-27 Aparna S. Varde , Jianyu Liang

In oncology, recurrence after treatment is one of the major challenges, related to patients' survival and quality of life. Conventionally, prediction of cancer relapse has always relied on clinical observation with statistical model…

Machine Learning · Computer Science 2025-02-25 Muhammad Umer Qayyum , Muhammad Fahad , Nasrullah Abbasi

Estimating heterogeneous treatment effects (HTEs) is crucial for precision medicine. While multiple studies can improve the generalizability of results, leveraging them for estimation is statistically challenging. Existing approaches often…

Methodology · Statistics 2025-12-22 Cathy Shyr , Boyu Ren , Prasad Patil , Giovanni Parmigiani

In light of the increasing interest in G9a's role in neuroscience, three machine learning (ML) models, that are time efficient and cost effective, were developed to support researchers in this area. The models are based on data provided by…

Quantitative Methods · Quantitative Biology 2025-08-12 Mariya L. Ivanova , Nicola Russo , Konstantin Nikolic

Predicting the consensus structure of a set of aligned RNA homologs is a convenient method to find conserved structures in an RNA genome, which has many applications including viral diagnostics and therapeutics. However, the most commonly…

Biomolecules · Quantitative Biology 2024-07-08 Apoorv Malik , Liang Zhang , Milan Gautam , Ning Dai , Sizhen Li , He Zhang , David H. Mathews , Liang Huang

Multivariate time series (MTS) anomaly detection is essential for maintaining the reliability of industrial systems, yet real-world deployment is hindered by two critical challenges: training data contamination (noises and hidden anomalies)…

Machine Learning · Computer Science 2025-10-28 Songhan Zhang , Yuanhao Lai , Pengfei Zheng , Boxi Yu , Xiaoying Tang , Qiuai Fu , Pinjia He

The development of accessible screening tools for early cancer detection in dogs represents a significant challenge in veterinary medicine. Routine laboratory data offer a promising, low-cost source for such tools, but their utility is…

Machine Learning · Computer Science 2025-12-11 Shumin Li

Plasma is defined as the fourth state of matter and non-thermal plasma can be produced at atmospheric pressure under a high electrical field. The strong and broad-spectrum antimicrobial effect of plasma-activated liquids (PALs) is now well…

Machine Learning · Computer Science 2022-07-27 Mehmet Akif Ozdemir , Gizem Dilara Ozdemir , Merve Gul , Onan Guren , Utku Kursat Ercan

Machine learning (ML) with in situ diagnostics offers a transformative approach to accelerate, understand, and control thin film synthesis by uncovering relationships between synthesis conditions and material properties. In this study, we…