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Identifying the effects of new interventions from data is a significant challenge found across a wide range of the empirical sciences. A well-known strategy for identifying such effects is Pearl's front-door (FD) criterion (Pearl, 1995).…

Methodology · Statistics 2022-10-17 Hyunchai Jeong , Jin Tian , Elias Bareinboim

Architectural Design Rewriting (ADR, for short) is a rule-based formal framework for modelling the evolution of architectures of distributed systems. Rules allow ADR graphs to be refined. After equipping ADR with a simple logic, we equip…

Logic in Computer Science · Computer Science 2012-12-19 Kyriakos Poyias , Emilio Tuosto

Causal effect estimation from observational data is a fundamental task in empirical sciences. It becomes particularly challenging when unobserved confounders are involved in a system. This paper focuses on front-door adjustment -- a classic…

Artificial Intelligence · Computer Science 2024-01-29 Marcel Wienöbst , Benito van der Zander , Maciej Liśkiewicz

An essential and challenging problem in causal inference is causal effect estimation from observational data. The problem becomes more difficult with the presence of unobserved confounding variables. The front-door adjustment is a practical…

Machine Learning · Computer Science 2023-10-04 Ziqi Xu , Debo Cheng , Jiuyong Li , Jixue Liu , Lin Liu , Kui Yu

In contemporary research, online error control is often required, where an error criterion, such as familywise error rate (FWER) or false discovery rate (FDR), shall remain under control while testing an a priori unbounded sequence of…

Methodology · Statistics 2024-09-13 Lasse Fischer , Marta Bofill Roig , Werner Brannath

Causal effect estimation from data typically requires assumptions about the cause-effect relations either explicitly in the form of a causal graph structure within the Pearlian framework, or implicitly in terms of (conditional) independence…

Machine Learning · Computer Science 2023-06-21 Abhin Shah , Karthikeyan Shanmugam , Murat Kocaoglu

Observational studies in fields such as epidemiology often rely on covariate adjustment to estimate causal effects. Classical graphical criteria, like the back-door criterion and the generalized adjustment criterion, are powerful tools for…

Methodology · Statistics 2025-12-24 Isabela Belciug , Simon Ferreira , Charles K. Assaad

In the estimation of causal effects, one common method for removing the influence of confounders is to adjust the variables that satisfy the back-door criterion. However, it is not always possible to uniquely determine sets of such…

Machine Learning · Computer Science 2025-02-06 Atsushi Noda , Takashi Isozaki

In many large scale multiple testing applications, the hypotheses often have a known graphical structure, such as gene ontology in gene expression data. Exploiting this graphical structure in multiple testing procedures can improve power as…

Methodology · Statistics 2018-12-04 Wenge Guo , Gavin Lynch , Joseph P. Romano

We generalize Pearl's back-door criterion for directed acyclic graphs (DAGs) to more general types of graphs that describe Markov equivalence classes of DAGs and/or allow for arbitrarily many hidden variables. We also give easily checkable…

Methodology · Statistics 2015-06-04 Marloes H. Maathuis , Diego Colombo

A dynamic graph algorithm is a data structure that answers queries about a property of the current graph while supporting graph modifications such as edge insertions and deletions. Prior work has shown strong conditional lower bounds for…

Data Structures and Algorithms · Computer Science 2023-01-30 Monika Henzinger , Ami Paz , A. R. Sricharan

Recent studies show that graph neural networks (GNNs) are vulnerable to backdoor attacks. Existing backdoor attacks against GNNs use fixed-pattern triggers and lack reasonable trigger constraints, overlooking individual graph…

Machine Learning · Computer Science 2025-03-13 Xuewen Dong , Jiachen Li , Shujun Li , Zhichao You , Qiang Qu , Yaroslav Kholodov , Yulong Shen

Motivation: In microarray analysis, special consideration must be given to the issues of multiple statistical tests and typically p-values are adjusted to control family-wise error rate (FWER) or false discovery rate (FDR). FDR metrics have…

Quantitative Methods · Quantitative Biology 2007-05-23 Rishi L. Khan , Rajanikanth Vadigepalli , Guang Gao , James S. Schwaber

Covariate adjustment is a widely used approach to estimate total causal effects from observational data. Several graphical criteria have been developed in recent years to identify valid covariates for adjustment from graphical causal…

Statistics Theory · Mathematics 2015-07-07 Emilija Perković , Johannes Textor , Markus Kalisch , Marloes H. Maathuis

The identification theory for causal effects in directed acyclic graphs (DAGs) with hidden variables is well established, but methods for estimating and inferring functionals that extend beyond the g-formula remain underdeveloped. Previous…

Methodology · Statistics 2025-09-12 Anna Guo , Razieh Nabi

Functional dependence graph (FDG) is an important class of directed graph that captures the dominance relationship among a set of variables. FDG is frequently used in calculating network coding capacity bounds. However, the order of FDG is…

Information Theory · Computer Science 2015-03-20 Xiaoli Xu , Satyajit Thakor , Yong Liang Guan

Computational biology offers immense potential for reducing the high costs and protracted cycles of new drug development through adverse drug reaction (ADR) prediction. However, current methods remain impeded by drug data scarcity-induced…

Machine Learning · Computer Science 2026-01-06 Yuyan Pi , Min Jin , Wentao Xie , Xinhua Liu

How to improve discriminative feature learning is central in classification. Existing works address this problem by explicitly increasing inter-class separability and intra-class similarity, whether by constructing positive and negative…

Machine Learning · Computer Science 2024-08-21 Qingsong Zhao , Yi Wang , Shuguang Dou , Chen Gong , Yin Wang , Cairong Zhao

When simultaneously testing multiple hypotheses, the usual approach in the context of confirmatory clinical trials is to control the familywise error rate (FWER), which bounds the probability of making at least one false rejection. In many…

Methodology · Statistics 2021-05-20 David S. Robertson , James M. S. Wason , Frank Bretz

Recent studies have revealed that GNNs are highly susceptible to multiple adversarial attacks. Among these, graph backdoor attacks pose one of the most prominent threats, where attackers cause models to misclassify by learning the…

Cryptography and Security · Computer Science 2024-10-21 Hao Sui , Bing Chen , Jiale Zhang , Chengcheng Zhu , Di Wu , Qinghua Lu , Guodong Long
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