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We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

We present a deep learning framework for probabilistic pixel-wise semantic segmentation, which we term Bayesian SegNet. Semantic segmentation is an important tool for visual scene understanding and a meaningful measure of uncertainty is…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Alex Kendall , Vijay Badrinarayanan , Roberto Cipolla

Identification of tumor margins is essential for surgical decision-making for glioblastoma patients and provides reliable assistance for neurosurgeons. Despite improvements in deep learning architectures for tumor segmentation over the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Tianyi Ren , Abhishek Sharma , Juampablo Heras Rivera , Harshitha Rebala , Ethan Honey , Agamdeep Chopra , Jacob Ruzevick , Mehmet Kurt

Accurate automatic medical image segmentation relies on high-quality, dense annotations, which are costly and time-consuming. Weakly supervised learning provides a more efficient alternative by leveraging sparse and coarse annotations…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Dongdong Meng , Sheng Li , Hao Wu , Suqing Tian , Wenjun Ma , Guoping Wang , Xueqing Yan

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

Early detection and segmentation of skin lesions is crucial for timely diagnosis and treatment, necessary to improve the survival rate of patients. However, manual delineation is time consuming and subject to intra- and inter-observer…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Sulaiman Vesal , Shreyas Malakarjun Patil , Nishant Ravikumar , Andreas Maier

The performance of deep segmentation models often degrades due to distribution shifts in image intensities between the training and test data sets. This is particularly pronounced in multi-centre studies involving data acquired using…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Zhendong Liu , Van Manh , Xin Yang , Xiaoqiong Huang , Karim Lekadir , Víctor Campello , Nishant Ravikumar , Alejandro F Frangi , Dong Ni

Precise medical image segmentation is fundamental for enabling computer aided diagnosis and effective treatment planning. Traditional models that rely solely on visual features often struggle when confronted with ambiguous or low contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ashfak Yeafi , Parthaw Goswami , Md Khairul Islam , Ashifa Islam Shamme

Semi-supervised learning (SSL) aims to help reduce the cost of the manual labelling process by leveraging a substantial pool of unlabelled data alongside a limited set of labelled data during the training phase. Since pixel-level manual…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Wanli Ma , Oktay Karakus , Paul L. Rosin

Efficient medical image segmentation aims to provide accurate pixel-wise predictions for medical images with a lightweight implementation framework. However, lightweight frameworks generally fail to achieve superior performance and suffer…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Xingqun Qi , Zhuojie Wu , Min Ren , Muyi Sun , Caifeng Shan , Zhenan Sun

Accurate and reliable brain tumor segmentation, particularly when dealing with missing modalities, remains a critical challenge in medical image analysis. Previous studies have not fully resolved the challenges of tumor boundary…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Shenghao Zhu , Yifei Chen , Weihong Chen , Yuanhan Wang , Chang Liu , Shuo Jiang , Feiwei Qin , Changmiao Wang

Deploying medical image segmentation models in routine clinical workflows is often constrained by on-premises infrastructure, where computational resources are fixed and cloud-based inference may be restricted by governance and security…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Qizhen Lan , Aaron Choi , Jun Ma , Bo Wang , Zhaogming Zhao , Xiaoqian Jiang , Yu-Chun Hsu

With the increase in the number of image data and the lack of corresponding labels, weakly supervised learning has drawn a lot of attention recently in computer vision tasks, especially in the fine-grained semantic segmentation problem. To…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Ke Zhang , Sihong Chen , Qi Ju , Yong Jiang , Yucong Li , Xin He

We present a novel neural network architecture, US-Net, for robust nuclei instance segmentation in histopathology images. The proposed framework integrates the nuclei detection and segmentation networks by sharing their outputs through the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Zhaoyang Xu , Faranak Sobhani , Carlos Fernandez Moro , Qianni Zhang

Convolutional neural networks have led to significant breakthroughs in the domain of medical image analysis. However, the task of breast cancer segmentation in whole-slide images (WSIs) is still underexplored. WSIs are large…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Nanqing Dong , Michael Kampffmeyer , Xiaodan Liang , Zeya Wang , Wei Dai , Eric P. Xing

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Extracting rich phenotype information, such as cell density and arrangement, from whole slide histology images (WSIs), requires analysis of large field of view, i.e more contexual information. This can be achieved through analyzing the…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Saarthak Kapse , Srijan Das , Prateek Prasanna

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Haotian Wang , Aleksandar Vakanski , Changfa Shi , Min Xian

Weakly supervised semantic segmentation (WSSS) trains dense pixel-level segmentation models from partial or coarse annotations such as bounding boxes, scribbles, or image-level tags. While recent work leverages foundation models such as the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Stefano Colamonaco , Andrei-Bogdan Florea , Jaron Maene