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Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

We propose a unified cross-domain transfer learning framework that leverages knowledge from multiple heterogeneous medical imaging datasets to improve performance across segmentation, classification, and object detection tasks. Our approach…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ceausescu Ciprian-Mihai , Anghelina Ion-Marian , Alexe Dumitru-Bogdan

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Accurate segmentation of maxillary sinus in panoramic X-ray images is essential for dental diagnosis and surgical planning; however, this task remains relatively underexplored in dental imaging research. Structural overlap, ambiguous…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Juha Park , Jiho Choi , Jong Pil Yun , Yong Chan Park , Han-Gyeol Yeom , Byung Do Lee , Sang Jun Lee

Early detection of skin cancer relies on precise segmentation of dermoscopic images of skin lesions. However, this task is challenging due to the irregular shape of the lesion, the lack of sharp borders, and the presence of artefacts such…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Shahzaib Iqbal , Muhammad Zeeshan , Mehwish Mehmood , Tariq M. Khan , Imran Razzak

Background and objectives: Colorectal cancer histopathological grading depends on accurate segmentation of glandular structures. Current deep learning approaches rely on large scale pixel level annotations that are labor intensive and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Hikmat Khan , Wei Chen , Muhammad Khalid Khan Niazi

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Accurate and efficient cell nuclei detection and classification in histopathological Whole Slide Images (WSIs) are pivotal for digital pathology applications. Traditional cell segmentation approaches, while commonly used, are…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Oscar Pina , Eduard Dorca , Verónica Vilaplana

Accurate skin-lesion segmentation remains a key technical challenge for computer-aided diagnosis of skin cancer. Convolutional neural networks, while effective, are constrained by limited receptive fields and thus struggle to model…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Pengyang Yu , Haoquan Wang , Gerard Marks , Tahar Kechadi , Laurence T. Yang , Sahraoui Dhelim , Nyothiri Aung

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Despite deep convolutional neural networks boost the performance of image classification and segmentation in digital pathology analysis, they are usually weak in interpretability for clinical applications or require heavy annotations to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yongxiang Huang , Albert C. S. Chung

Deep learning methods show promising results for overlapping cervical cell instance segmentation. However, in order to train a model with good generalization ability, voluminous pixel-level annotations are demanded which is quite expensive…

Computer Vision and Pattern Recognition · Computer Science 2020-07-22 Yanning Zhou , Hao Chen , Huangjing Lin , Pheng-Ann Heng

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsheng He , Xingyu Li

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham

Nodule segmentation from breast ultrasound images is challenging yet essential for the diagnosis. Weakly-supervised segmentation (WSS) can help reduce time-consuming and cumbersome manual annotation. Unlike existing weakly-supervised…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Yuhao Huang , Xin Yang , Yuxin Zou , Chaoyu Chen , Jian Wang , Haoran Dou , Nishant Ravikumar , Alejandro F Frangi , Jianqiao Zhou , Dong Ni

Recent advances have been made in applying convolutional neural networks to achieve more precise prediction results for medical image segmentation problems. However, the success of existing methods has highly relied on huge computational…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Dian Qin , Jiajun Bu , Zhe Liu , Xin Shen , Sheng Zhou , Jingjun Gu , Zhijua Wang , Lei Wu , Huifen Dai

There has been a steady increase in the incidence of skin cancer worldwide, with a high rate of mortality. Early detection and segmentation of skin lesions are crucial for timely diagnosis and treatment, necessary to improve the survival…

Computer Vision and Pattern Recognition · Computer Science 2019-12-04 Sulaiman Vesal , Nishant Ravikumar , Andreas Maier
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