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This article considers the receiver operating characteristic (ROC) curve analysis for medical data with non-ignorable missingness in the disease status. In the framework of the logistic regression models for both the disease status and the…

Methodology · Statistics 2024-11-27 Dingding Hu , Tao Yu , Pengfei Li

The identification of biomarkers with high predictive accuracy is a crucial task in medical research, as it can aid clinicians in making early decisions, thereby reducing morbidity and mortality in high-risk populations. Time-dependent…

Methodology · Statistics 2025-10-22 María Xosé Rodríguez-Álvarez , Vanda Inácio

Emergence of artificial intelligence techniques in biomedical applications urges the researchers to pay more attention on the uncertainty quantification (UQ) in machine-assisted medical decision making. For classification tasks, prior…

Machine Learning · Computer Science 2019-09-17 Xiaoyang Huang , Jiancheng Yang , Linguo Li , Haoran Deng , Bingbing Ni , Yi Xu

Background: Medical decision-making impacts both individual and public health. Clinical scores are commonly used among a wide variety of decision-making models for determining the degree of disease deterioration at the bedside. AutoScore…

In clinical practice, multiple biomarkers are used for disease diagnosis, but their individual accuracies are often suboptimal, with only a few proving directly relevant. Effectively selecting and combining biomarkers can significantly…

Methodology · Statistics 2025-09-03 Ao Sun , Zhanwang Deng , Jiahui Zhao , Hang Li , Xiao-Hua Zhou

With the increasing importance of safety requirements associated with the use of black box models, evaluation of selective answering capability of models has been critical. Area under the curve (AUC) is used as a metric for this purpose. We…

Computation and Language · Computer Science 2022-10-11 Swaroop Mishra , Anjana Arunkumar , Chitta Baral

The intention with this paper is to provide all the estimation concepts and techniques that are needed to implement a two-phases approach to the parametric estimation of probability of default (PD) curves. In the first phase of this…

Risk Management · Quantitative Finance 2010-03-05 Dirk Tasche

In diagnostic studies, researchers frequently encounter imperfect reference standards with some misclassified labels. Treating these as gold standards can bias receiver operating characteristic (ROC) curve analysis. To address this issue,…

Methodology · Statistics 2025-02-13 Yifan Sun , Peijun Sang , Qinglong Tian , Pengfei Li

In observational studies, potential unobserved confounding is a major barrier in isolating the average causal effect (ACE). In these scenarios, two main approaches are often used: confounder adjustment for causality (CAC) and instrumental…

Methodology · Statistics 2024-11-26 Roy S. Zawadzki , Daniel L. Gillen

Several efforts have been done to bring ROC analysis beyond (binary) classification, especially in regression. However, the mapping and possibilities of these proposals do not correspond to what we expect from the analysis of operating…

Statistics Theory · Mathematics 2013-10-17 Jose Hernandez-Orallo

The Kendall plot ($\K$-plot) is a plot measuring dependence between the components of a bivariate random variable. The $\K$-plot graphs the Kendall distribution function against the distribution function of $VU$, where $V$ and $U$ are…

Statistics Theory · Mathematics 2018-11-22 Albert Vexler , Georgios Afendras , Marianthi Markatou

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

In machine learning (ML), a widespread claim is that the area under the precision-recall curve (AUPRC) is a superior metric for model comparison to the area under the receiver operating characteristic (AUROC) for tasks with class imbalance.…

Machine Learning · Computer Science 2025-01-15 Matthew B. A. McDermott , Haoran Zhang , Lasse Hyldig Hansen , Giovanni Angelotti , Jack Gallifant

Link prediction is a paradigmatic and challenging problem in network science, which attempts to uncover missing links or predict future links, based on known topology. A fundamental but still unsolved issue is how to choose proper metrics…

Data Analysis, Statistics and Probability · Physics 2023-03-22 Tao Zhou

Many typical applications of object detection operate within a prescribed false-positive range. In this situation the performance of a detector should be assessed on the basis of the area under the ROC curve over that range, rather than…

Computer Vision and Pattern Recognition · Computer Science 2013-10-04 Sakrapee Paisitkriangkrai , Chunhua Shen , Anton van den Hengel

The area under the receiver operating characteristic curve (AUC) serves as a summary of a binary classifier's performance. Methods for estimating the AUC have been developed under a binormality assumption which restricts the distribution of…

Methodology · Statistics 2020-07-28 Zhe Wang , Ryan Martin

Top-k error has become a popular metric for large-scale classification benchmarks due to the inevitable semantic ambiguity among classes. Existing literature on top-k optimization generally focuses on the optimization method of the top-k…

Machine Learning · Computer Science 2024-07-11 Zitai Wang , Qianqian Xu , Zhiyong Yang , Yuan He , Xiaochun Cao , Qingming Huang

Receiver Operating Characteristic (ROC) curves are plots of true positive rate versus false positive rate which are used to evaluate binary classification algorithms. Because the Area Under the Curve (AUC) is a constant function of the…

Machine Learning · Computer Science 2023-02-23 Kyle R. Rust , Toby D. Hocking

Brain tumor is one of the leading causes of cancer-related death globally among children and adults. Precise classification of brain tumor grade (low-grade and high-grade glioma) at early stage plays a key role in successful prognosis and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Ruqian Hao , Khashayar Namdar , Lin Liu , Farzad Khalvati

Stochastic optimization of the Area Under the Precision-Recall Curve (AUPRC) is a crucial problem for machine learning. Although various algorithms have been extensively studied for AUPRC optimization, the generalization is only guaranteed…

Machine Learning · Computer Science 2022-09-28 Peisong Wen , Qianqian Xu , Zhiyong Yang , Yuan He , Qingming Huang
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