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One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

With the rapid development of classical and quantum machine learning, a large number of machine learning frameworks have been proposed. However, existing machine learning frameworks usually only focus on classical or quantum, rather than…

Quantum machine learning is one of the fields where quantum computers are expected to bring advantages over classical methods. However, the limited size of current computers restricts the exploitation of the full potential of quantum…

Quantum Physics · Physics 2025-11-10 Juan C. Boschero , Ward van der Schoot , Niels M. P. Neumann

Quantum computing promises to tackle technological and industrial problems insurmountable for classical computers. However, today's quantum computers still have limited demonstrable functionality, and it is expected that scaling up to…

Quantum machine learning aims to release the prowess of quantum computing to improve machine learning methods. By combining quantum computing methods with classical neural network techniques we aim to foster an increase of performance in…

High Energy Physics - Phenomenology · Physics 2021-03-17 Andrew Blance , Michael Spannowsky

In current noisy intermediate-scale quantum devices, hybrid quantum-classical neural networks (HQNNs) represent a promising solution that combines the strengths of classical machine learning with quantum computing capabilities. Compared to…

Quantum computing has the potential to surpass the capabilities of current classical computers when solving complex problems. Combinatorial optimization has emerged as one of the key target areas for quantum computers as problems found in…

Quantum Physics · Physics 2023-07-27 Juan Giraldo , José Ossorio , Norha M. Villegas , Gabriel Tamura , Ulrike Stege

Quantum machine learning (QML) is promising for potential speedups and improvements in conventional machine learning (ML) tasks (e.g., classification/regression). The search for ideal QML models is an active research field. This includes…

Quantum Physics · Physics 2022-02-07 Mahabubul Alam , Swaroop Ghosh

This work addresses the challenge of enabling practitioners without quantum expertise to transition from classical to hybrid quantum-classical machine learning workflows. We propose a three-stage framework: starting with a classical…

Deep learning is a modern approach to realize artificial intelligence. Many frameworks exist to implement the machine learning task; however, performance is limited by computing resources. Using a quantum computer to accelerate training is…

Quantum Physics · Physics 2019-01-29 Zhao-Yun Chen , Cheng Xue , Si-Ming Chen , Guo-Ping Guo

Machine Learning (ML) has been widely applied across numerous domains due to its ability to automatically identify informative patterns from data for various tasks. The availability of large-scale data and advanced computational power…

Quantum machine learning is a rapidly growing field at the intersection of quantum technology and artificial intelligence. This review provides a two-fold overview of several key approaches that can offer advancements in both the…

Quantum Physics · Physics 2023-03-07 Alexey Melnikov , Mohammad Kordzanganeh , Alexander Alodjants , Ray-Kuang Lee

Deep learning has been shown to be able to recognize data patterns better than humans in specific circumstances or contexts. In parallel, quantum computing has demonstrated to be able to output complex wave functions with a few number of…

Quantum Physics · Physics 2021-08-05 Junhua Liu , Kwan Hui Lim , Kristin L. Wood , Wei Huang , Chu Guo , He-Liang Huang

The development of quantum computers has been the stimulus that enables the realization of Quantum Machine Learning (QML), an area that integrates the calculational framework of quantum mechanics with the adaptive properties of classical…

Computational Engineering, Finance, and Science · Computer Science 2025-09-04 Bhavna Bose , Saurav Verma

Hybrid Quantum-Classical Machine Learning (ML) is an emerging field, amalgamating the strengths of both classical neural networks and quantum variational circuits on the current noisy intermediate-scale quantum devices. This paper performs…

We propose a classical-quantum hybrid algorithm for machine learning on near-term quantum processors, which we call quantum circuit learning. A quantum circuit driven by our framework learns a given task by tuning parameters implemented on…

Quantum Physics · Physics 2019-04-25 Kosuke Mitarai , Makoto Negoro , Masahiro Kitagawa , Keisuke Fujii

Convolutional Neural Networks (CNN) are used mainly to treat problems with many images characteristic of Deep Learning. In this work, we propose a hybrid image classification model to take advantage of quantum and classical computing. The…

Quantum Physics · Physics 2021-04-10 Parfait Atchade-Adelomou , Guillermo Alonso-Linaje

Quantum machine learning (QML) is an emerging field that investigates the capabilities of quantum computers for learning tasks. While QML models can theoretically offer advantages such as exponential speed-ups, challenges in data loading…

Quantum Physics · Physics 2025-11-03 Florian J. Kiwit , Bernhard Jobst , Andre Luckow , Frank Pollmann , Carlos A. Riofrío

In this paper, a novel quantum classical hybrid framework is proposed that synergizes quantum with Classical Reinforcement Learning. By leveraging the inherent parallelism of quantum computing, the proposed approach generates robust Q…

Machine Learning · Computer Science 2025-05-21 Sahil Tomar , Shamshe Alam , Sandeep Kumar , Amit Mathur

Quantum circuit simulations play a critical role in bridging the gap between theoretical quantum algorithms and their practical realization on physical quantum hardware, yet they face computational challenges due to the exponential growth…

Quantum Physics · Physics 2025-08-20 Ji-Hoon Kang , Hoon Ryu