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The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

The multi-task learning ($MTL$) paradigm aims to simultaneously learn multiple tasks within a single model capturing higher-level, more general hidden patterns that are shared by the tasks. In deep learning, a significant challenge in the…

Machine Learning · Computer Science 2025-06-09 Thomas Borsani , Andrea Rosani , Giuseppe Nicosia , Giuseppe Di Fatta

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

Since annotating medical images for segmentation tasks commonly incurs expensive costs, it is highly desirable to design an annotation-efficient method to alleviate the annotation burden. Recently, contrastive learning has exhibited a great…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Yixuan Wu , Jintai Chen , Jiahuan Yan , Yiheng Zhu , Danny Z. Chen , Jian Wu

Surgical AI often involves multiple tasks within a single procedure, like phase recognition or assessing the Critical View of Safety in laparoscopic cholecystectomy. Traditional models, built for one task at a time, lack flexibility,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Soham Walimbe , Britty Baby , Vinkle Srivastav , Nicolas Padoy

Self-supervised learning (SSL) has emerged as a promising paradigm for addressing the annotation bottleneck in medical imaging by learning representations from unlabeled data. However, its effectiveness depends heavily on the design of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Chathura Wimalasiri

Self-supervised learning (SSL) has been successful in building patch embeddings of small histology images (e.g., 224x224 pixels), but scaling these models to learn slide embeddings from the entirety of giga-pixel whole-slide images (WSIs)…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Guillaume Jaume , Lukas Oldenburg , Anurag Vaidya , Richard J. Chen , Drew F. K. Williamson , Thomas Peeters , Andrew H. Song , Faisal Mahmood

Multi-task learning (MTL) is a subfield of machine learning with important applications, but the multi-objective nature of optimization in MTL leads to difficulties in balancing training between tasks. The best MTL optimization methods…

Machine Learning · Computer Science 2021-09-20 Michael Crawshaw , Jana Košecká

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

Accurate segmentation of the optic disc and cup is critical for the early diagnosis and management of ocular diseases such as glaucoma. However, segmentation models trained on one dataset often suffer significant performance degradation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Rini Smita Thakur , Rajeev Ranjan Dwivedi , Vinod K Kurmi

Multitask learning is a widely used paradigm for training models on diverse tasks, with applications ranging from graph neural networks to language model fine-tuning. Since tasks may interfere with each other, a key notion for modeling…

Machine Learning · Computer Science 2024-11-22 Dongyue Li , Aneesh Sharma , Hongyang R. Zhang

Accurate cell type annotation is a crucial step in analyzing single-cell RNA sequencing (scRNA-seq) data, which provides valuable insights into cellular heterogeneity. However, due to the high dimensionality and prevalence of zero elements…

Machine Learning · Computer Science 2025-08-14 Huifa Li , Jie Fu , Xinlin Zhuang , Haolin Yang , Xinpeng Ling , Tong Cheng , Haochen xue , Imran Razzak , Zhili Chen

Scene Graph Generation (SGG) endeavors to predict the relationships between subjects and objects in a given image. Nevertheless, the long-tail distribution of relations often leads to biased prediction on coarse labels, presenting a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Qishen Chen , Jianzhi Liu , Xinyu Lyu , Lianli Gao , Heng Tao Shen , Jingkuan Song

Accurate segmentation of cell nuclei in histopathology images is essential for numerous biomedical research and clinical applications. However, existing cell nucleus segmentation methods only consider a single dataset (i.e., primary…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Jiahe Qian , Yaoyu Fang , Jinkui Hao , Bo Zhou

Accurate cancer diagnosis remains a critical challenge in digital pathology, largely due to the gigapixel size and complex spatial relationships present in whole slide images. Traditional multiple instance learning (MIL) methods often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Kechun Liu , Wenjun Wu , Joann G. Elmore , Linda G. Shapiro

Label scarcity has been a long-standing issue for biomedical image segmentation, due to high annotation costs and professional requirements. Recently, active learning (AL) strategies strive to reduce annotation costs by querying a small…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Ziyuan Zhao , Wenjing Lu , Zeng Zeng , Kaixin Xu , Bharadwaj Veeravalli , Cuntai Guan

Medical image analysis requires substantial labeled data for model training, yet expert annotation is expensive and time-consuming. Active learning (AL) addresses this challenge by strategically selecting the most informative samples for…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Ifrat Ikhtear Uddin , Longwei Wang , Xiao Qin , Yang Zhou , KC Santosh

Training large language models (LLMs) typically relies on adaptive optimizers like Adam (Kingma & Ba, 2015) which store additional state information to accelerate convergence but incur significant memory overhead. Recent efforts, such as…

Machine Learning · Computer Science 2025-02-11 Meyer Scetbon , Chao Ma , Wenbo Gong , Edward Meeds

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter
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